Patents by Inventor John Michael Cox

John Michael Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6022976
    Abstract: A process for the production of hydroxy-substituted oxazolidinones, particularly 5-hydroxyoxazolidinones, which are useful as intermediates in the synthesis of herbicidally active compounds, comprising treating a hydroxythiazolidinone with an oxidizing agent.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: February 8, 2000
    Assignee: ZENECA Limited
    Inventors: Glynn Mitchell, John Michael Cox, Shaheen Khatoon Vohra
  • Patent number: 5922644
    Abstract: A herbicidal compound of formula (I) ##STR1## or a salt, tautomer or cyclic derivative thereof; where R.sup.1 and R.sup.2 are hydrogen and A is an optionally substituted saturated or unsaturated chain or ring of three carbon atoms.Methods for preparing these compounds, intermediates used in the preparation and herbicidal compositions containing them are also described and claimed.
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: July 13, 1999
    Assignee: Zeneca Limited
    Inventors: John Michael Cox, Peter Bellini, Roger Barrett, Russell Martin Ellis, Timothy Robert Hawkes
  • Patent number: 5688962
    Abstract: A process for the synthesis of a compound of general formula II: ##STR1## wherein: R.sup.2 and R.sup.3 are each independently hydrogen or C.sub.1 -C.sub.4 alkyl;A is an aromatic or heteroaromatic ring system optionally substituted with one or more substituents as defined herein; and in which any ring nitrogen atom may be quaternised or oxidised;alternatively, any two substituents of the group A may combine to form a fused 5- or 6-membered saturated or partially saturated carbocyclic or heterocyclic ring in which any carbon or quaternised nitrogen atom may be substituted with any of the groups defined herein for A or in which a ring carbon atom may be oxidised;the process comprising cyclising a compound of general formula VII: ##STR2## wherein A, R.sup.2 and R.sup.3 are as defined for general formula II, R.sup.20 is hydrogen, benzyl or benzyl substituted with up to five substituents selected from halo, C.sub.1 -C.sub.6 alkyl, O(C.sub.1 -C.sub.6 alkyl) or nitro and R.sub.21 is C.sub.1 -C.sub.
    Type: Grant
    Filed: May 16, 1996
    Date of Patent: November 18, 1997
    Assignee: Zeneca Limited
    Inventors: John Michael Cox, David Philip John Pearson, Anthony Marian Kozakiewicz, Richard Butler Moore, Glynn Mitchell, David William Langton, Russell Ellis
  • Patent number: 5670656
    Abstract: A process for the preparation of a compound of general formula II: ##STR1## wherein R.sup.1 is hydrogen, or C.sub.1 -C.sub.10 hydrocarbyl or heterocyclyl having 3 to 8 ring atoms, either of which may optionally be substituted; each R.sup.2, R.sup.3, R.sup.4 and R.sup.5 is independently hydrogen or C.sub.1 -C.sub.4 alkyl; A is an optionally substituted aromatic or heteroaromatic ring system; and R.sup.21 is hydrogen, halogen, OH or OCONHR.sup.1, wherein R.sup.1 is as defined above; the process comprising cyclizing a compound of general formula III: ##STR2## wherein A, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.21 are as defined in general formula II and R.sup.25 is a leaving group such as a halogen atom; under basic conditions.
    Type: Grant
    Filed: May 24, 1996
    Date of Patent: September 23, 1997
    Assignee: Zeneca Limited
    Inventors: John Michael Cox, Kevin James Gillen, Russell Martin Ellis, Shaheen Khatoon Vohra, Stephen Christopher Smith, Ian Richard Matthews
  • Patent number: 4087422
    Abstract: Dihydrotetrazolo [1,5-a] quinazolines having the formula: ##STR1## wherein (a) n is 0, X is oxygen, and R is optionally unsubstituted alkyl, alkenyl of at least 4 carbon atoms, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, amino or substituted aryl; or (b) n is 1 or 2, X is oxygen, R is hydrogen, or optionally-substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, or amino, and R.sup.1 is hydroxy, halogen, nitro, alkyl or alkoxy or (c) n is 0, 1 or 2, X is sulphur, R is hydrogen, or optionally-substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, or amino, and R.sup.1 is hydroxy, halogen, nitro, alkyl or alkoxy; or (d) n is 0, 1 or 2, X is NR.sub.2 where R.sub.2 is hydrogen, alkyl having 1 to 10 carbon atoms, benzyl or hydroxyalkyl, R is optionally-substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, or amino, and R.sup.1 is hydroxy, halogen, nitro, alkyl or alkoxy; and salts thereof. These compounds demonstrate pesticidal activity.
    Type: Grant
    Filed: June 13, 1977
    Date of Patent: May 2, 1978
    Assignee: Imperial Chemical Industries Limited
    Inventors: Raymond Alexander Bowie, John Michael Cox, Gordon Michael Farrell, Margaret Claire Shephard
  • Patent number: 4059703
    Abstract: Pesticidal tetrazole derivatives having the formula: ##STR1## wherein n is 0, 1, 2, 3 or 4; R.sup.1 is OH, halogen, alkyl, alkoxy, alkylthio, alkylsulphonyl, NO.sub.2, NH.sub.2 (optionally substituted), acyl, aroyl, CN, carboxy or sulphonic-acid or -ester or -amide; R.sup.2 is hydrogen or optionally-substituted alkyl; R.sup.3 and R.sup.4 are hydrogen or optionally-substituted alkyl, aryl, cycloalkyl or acetyl but R.sup.4 is not aryl or cycloalkyl if R.sup.3 is one of these two groups; and salts thereof when R.sup.2 is hydrogen.
    Type: Grant
    Filed: August 6, 1976
    Date of Patent: November 22, 1977
    Assignee: Imperial Chemical Industries Limited
    Inventors: Raymond Alexander Burrell, John Michael Cox
  • Patent number: 4056384
    Abstract: Dihydrotetrazolo [1,5-a] quinazolines having the formula ##STR1## wherein (a) n is zero, X is oxygen, and R is optionally unsubstituted alkyl, alkenyl of at least 4 carbon atoms, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, amino or substituted aryl; or (b) n is 1 or 2, X is oxygen, R is hydrogen, or optionally-substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, or amino, and R.sup.1 is hydroxy, halogen, nitro, alkyl or alkoxy or (c) n is zero, 1 or 2, X is sulphur, R is hydrogen, or optionally-substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, or amino, and R.sup.1 is hydroxy, halogen, nitro, alkyl or alkoxy; or (d) n is 0, 1 or 2, X is NR.sub.2 where R.sub.2 is hydrogen, alkyl having 1 to 10 carbon atoms, benzyl or hydroxyalkyl, R is optionally-substituted alkyl, alkenyl, alkynyl, aryl, aralkyl, alkylthio, cycloalkyl, or amino, and R.sup.1 is hydroxy, halogen, nitro, alkyl or alkoxy; and salts thereof. These compounds demonstrate pesticidal activity.
    Type: Grant
    Filed: August 25, 1975
    Date of Patent: November 1, 1977
    Assignee: Imperial Chemical Industries Limited
    Inventors: Raymond Alexander Bowie, John Michael Cox, Gordon Michael Farrell, Margaret Claire Shephard