Abstract: The present invention provides immunogenic compositions having one or more polysaccharide-protein conjugates in which one or more polysaccharides from Streptococcus pneumoniae bacterial capsules are conjugated to a carrier protein in an aprotic solvent such as dimethylsulfoxide (DMSO). The present invention also provides methods for providing an enhanced immune response to a pneumococcal polysaccharide protein conjugate vaccine comprising administering to a human subject an immunogenic composition comprising polysaccharide-protein conjugates prepared in DMSO conditions.

Abstract: The present invention provides immunogenic compositions having one or more polysaccharide-protein conjugates in which one or more polysaccharides from Streptococcus pneumoniae bacterial capsules are conjugated to a carrier protein in an aprotic solvent such as dimethylsulfoxide (DMSO). The present invention also provides methods for providing an enhanced immune response to a pneumococcal polysaccharide protein conjugate vaccine comprising administering to a human subject an immunogenic composition comprising polysaccharide-protein conjugates prepared in DMSO conditions.

Abstract: An exemplary computer implemented method for prescribing a therapeutic regimen is provided. The computer implemented method includes receiving, by one or more computing devices, prescription information for a patient. The prescription information includes information representing a medical condition diagnosed by a prescriber. An identifier or identifiers may be extracted from the prescription information. At least one identifier indicates a diagnosis associated with the diagnosed medical condition. Thereupon, virtual kit information from a virtual treatment kit having one or more updatable components may be identified from a database using the identifier. Each of the updatable components includes component information representing at least one predetermined medication and a treatment plan for administering the predetermined medication for treating the identified medical condition.

Abstract: An exhaust treatment system for an engine includes a regeneration device being in receipt of exhaust from the engine and positioned upstream of a diesel particulate filter. A compressor provides a source of compressed air. An air/fuel nozzle is coupled to the regeneration device, in receipt of a fuel supply as well as the compressed air. The fuel and compressed air are forced through an orifice of the nozzle to atomize the fuel. A bypass line provides compressed air from the compressor to the regeneration device without passing through the orifice of the nozzle. A valve is operable to allow compressed air to flow through the bypass line when a predetermined condition exists.

Abstract: An exhaust treatment system for an engine includes a regeneration device being in receipt of exhaust from the engine and positioned upstream of a diesel particulate filter. A compressor provides a source of compressed air. An air/fuel nozzle is coupled to the regeneration device, in receipt of a fuel supply as well as the compressed air. The fuel and compressed air are forced through an orifice of the nozzle to atomize the fuel. A bypass line provides compressed air from the compressor to the regeneration device without passing through the orifice of the nozzle. A valve is operable to allow compressed air to flow through the bypass line when a predetermined condition exists.

Abstract: An exhaust treatment system for an engine includes a regeneration device being in receipt of exhaust from the engine and positioned upstream of a diesel particulate filter. A compressor provides a source of compressed air. An air/fuel nozzle is coupled to the regeneration device, in receipt of a fuel supply as well as the compressed air. The fuel and compressed air are forced through an orifice of the nozzle to atomize the fuel. A bypass line provides compressed air from the compressor to the regeneration device without passing through the orifice of the nozzle. A valve is operable to allow compressed air to flow through the bypass line when a predetermined condition exists.

Abstract: In various embodiments, shipping container systems are described included an extended tunnel flooring system with a steel floor piece running lengthwise down the center of the extended tunnel floor, and an Omega flooring system including alternating lengthwise strips of 6 wood floor pieces and 5 floor steel pieces on a structure of support beams reinforced with steel gusset plate.

Abstract: In various embodiments, shipping container systems are described included an extended tunnel flooring system with a steel floor piece running lengthwise down the center of the extended tunnel floor, and an Omega flooring system including alternating lengthwise strips of 6 wood floor pieces and 5 floor steel pieces on a structure of support beams reinforced with steel gusset plate.