Abstract: Foundry coke products, and associated methods and systems for melting iron in a cupola furnace with the coke products are disclosed herein. A representative method can include receiving a population of coke products and iron in a cupola furnace, and melting the iron in the cupola furnace to form molten iron having a carbon content higher than a carbon content of the received iron. The coke products can comprise (i) an elongate shape including a length:width dimension of at least 1.5:1, (ii) an ash fusion temperature of no more than 2400° F., and/or (iii) a coke reactivity index (CRI) of at least 30%.

Abstract: A method of making a frozen cream product containing a range between 0-15% alcoholic beverage by volume without using any additives, preservatives, unnatural stabilizers and unnatural emulsifiers such that a combined cream product containing the alcoholic beverage will not undergo alcohol-water separation during the processes of making the combined cream product containing alcohol or during the process of freezing the combined cream product containing alcohol to form the frozen cream product containing alcohol.

Abstract: An analyte sensor system is provided. The system includes a base configured to attach to a skin of a host. The base includes an analyte sensor configured to generate a sensor signal indicative of an analyte concentration level of the host, a battery, and a first plurality of contacts. The system includes a sensor electronics module configured to releasably couple to the base. The sensor electronics module includes a second plurality of contacts, each configured to make electrical contact with a respective one of the first plurality of contacts, and a wireless transceiver configured to transmit a wireless signal based at least in part on the sensor signal. The system includes a first sealing member configured to provide a seal around the first and second plurality of contacts within a first cavity. Related analyte sensor systems, analyte sensor base assemblies and methods are also provided.

Abstract: A respirator system includes a respirator with an air filter, a flow generator with a sensorless DC motor, a mask, a processor, a sensor, an electric power source, and a wireless transceiver. The respirator filters air, increase the pressure of the air, delivers the air to the mask at a pressure above ambient, gathers data with the sensor about operation of the respirator, and transmits the data. An intermediate electronic device is separate and remote from the respirator, and is configured to receive the transmitted data process the data, and re-transmit the data. A computer receives the data, processes the data and generates at least one report regarding the respirator or a user of the respirator.

Abstract: A user equipment (UE) is described. The UE includes receiving circuitry configured to receive system information comprising first information of first time domain resource assignment for a physical downlink shared channel (PDSCH). The receiving circuitry is also configured to receive a UE-specific radio resource control (RRC) signal comprising second information of second time domain resource assignment for a PDSCH. The receiving circuitry is also configured to perform, based on a detection of a physical downlink control channel (PDCCH), the PDSCH reception according to either the first information of the first time domain resource assignment or the second information of the second time domain resource assignment.

Abstract: Systems for applying a transcutaneous monitor to a person can include a telescoping assembly, a sensor, and a base with adhesive to couple the sensor to skin. The sensor can be located within the telescoping assembly while the base protrudes from a distal end of the system. The system can be configured to couple the sensor to the base by compressing the telescoping assembly.

Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.

Abstract: The present invention relates to methods of treating cancer using compounds that inhibit Son of sevenless homolog 1 (SOS1) activity and pharmaceutical compositions containing such compounds.

Abstract: The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

Abstract: A structured light system includes a camera module and a dot projection module. The dot projection module includes a submount, an emitter array disposed on the submount, and a diffractive optical element (DOE) disposed over the emitter array. The emitter array includes a plurality of emitters arranged in a periodic emitter pattern and the emitter array is oriented at a non-zero angle relative to a rectilinear axis of the submount.

Abstract: Techniques are described for performing fetal heart rate (FHR) analytics using machine learning techniques. According to an embodiment, computer-implemented method comprises training a machine learning model using a supervised machine learning process to identify patterns in training cardiotocograph data that correspond to defined physiological events associated with respective fetuses and mothers of the fetuses represented in the training cardiotocograph data. The method further comprises receiving new cardiotocograph data for a fetus and mother in real-time over a period of labor and applying the machine learning model to the new cardiotocograph data as it is received to identify the patterns in the new cardiotocograph data.

Abstract: A reader system for a tire with an integrated radio frequency identification (RFID) and tire pressure monitoring system (TPMS) sensor, in which the integrated RFID and TPMS sensor is mounted on the tire, is provided. The reader system includes at least one antenna that is external to the tire. The at least one antenna is mounted on a vehicle on which the tire is mounted in a location proximate the tire. The at least one antenna is in electronic communication with the integrated RFID and TPMS sensor. A reader is mounted on the vehicle and is also in electronic communication with the at least one antenna. The at least one antenna relays a signal from the integrated RFID and TPMS sensor to the reader. A display device is in electronic communication with the reader to receive and display data from the integrated RFID and TPMS sensor.

Abstract: A robotic system and methods are disclosed. A common axis is defined for an instrument and an energy applicator extending from the instrument. A manipulator has a plurality of links and actuators configured to move the links to position the instrument and energy applicator. A force/torque sensor coupled to the manipulator generates an output in response to forces/torques applied to the instrument. Controller(s) defines a centering point that intersects the common axis. Controller(s) model the instrument and the energy applicator as a virtual rigid body and determine forces/torques to apply to the virtual rigid body, which are determined, in part, based on the output of the force/torque sensor. Controller(s) control the manipulator to advance the energy applicator based on the determined forces/torques applied to the virtual rigid body and reorient the instrument such that the common axis pivots about the centering point during advancement of the energy applicator.

Abstract: Exemplary embodiments include a device that may serve as a drink dispenser for beverage cans. The device may be shaped like a keg. The device may include a portion to contain, cool, and dispense the beverage cans and a portion to contain ice to provide cooling, as well as contain additional beverage containers. The device may include up to five tubes with each tube capable of containing up to four beverage containers in the form of cans. A dispensing mechanism may be located at the lower end of each tube to dispense the beverage cans form the device. The tube structure may provide for cooling of the beverage containers within each tube. The device may be portable and may have a cart that can be used for transportation of the device. The device may be detachable from the cart.

Abstract: Embodiments of the present application relate to porous polymeric beads solid support for use in oligonucleotide synthesis and the method of producing and using the same. Further embodiments relate to porous polymeric beads and method for preparing and using the same.

Abstract: Genetically engineered immune cells such as T cells having a disrupted CD83 gene and optionally expressing a chimeric antigen receptor (CAR) and therapeutic applications thereof. Such genetically engineered immune cells may further comprise a disrupted TRAC gene, a disrupted ?2M gene, or a combination thereof.

Abstract: Methods, systems and devices that allow independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that does not require voltage applied to the sample reservoir and can allow for in-channel focusing methods to be used. The methods, systems and devices are particularly suitable for use with a mass spectrometer.

Abstract: An apparatus is provided to test valves. The apparatus includes a base and an actuation mechanism with an actuator having a first end coupled to the base and a second end retractably extends from the base. The apparatus further includes a common platform with a first surface and a second surface. The first surface coupled to the second end of the actuator and moves from the base, based on an extension of the actuator. The apparatus further includes a plurality of engagement members each of which includes a first portion coupled to the first surface and a second portion coupled to the second surface. The apparatus further includes a plurality of sensors coupled to the plurality of engagement members such that each sensor of the plurality of sensors is coupled to corresponding member of the plurality of engagement members and coupled with a valve associated with a machine.

Abstract: A predictive model is described that can predict parameter concentrations in the future based on initial, measured concentrations and historical data. A plurality of multivariate techniques can be used to construct the predictive model capable of forecasting concentrations over multiple and diverse cell lines. The predictive model is also scalable. In one embodiment, a future lactate concentration trajectory is determined and at least one condition within a bioreactor is changed or modified to maintain lactate concentration within desired ranges.

Abstract: A system includes a first robotic machine having a first set of capabilities for interacting with a target object on stationary equipment; a second robotic machine having a second set of capabilities for interacting with the target object; and a task manager that can determine capability requirements to perform a task on the target object. The task has an associated series of sub-tasks. The task manager can assign a first sequence of sub-tasks for performance by the first robotic machine based on the first set of capabilities and a second sequence of sub-tasks for performance by the second robotic machine based on the second set of capabilities. The first and second robotic machines can coordinate performance of the first sequence of sub-tasks by the first robotic machine with performance of the second sequence of sub-tasks by the second robotic machine to accomplish the task.