Abstract: Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (“diaminophenothiazinium compounds”) including Methylthioninium Chloride (MTC) (Methylene Blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities Azure A, B, C and MVB. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.

Abstract: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula: wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.

Abstract: Disclosed herein are methods, apparatus, and systems for iris recognition. A method includes acquiring at least two angularly differentiated iris images from a subject needing access, processing each of the at least two angularly differentiated iris images to generate at least one boundary delineated image from one of the at least two angularly differentiated iris images, applying image comparative analysis to the at least two angularly differentiated iris images to generate a boundary delineated image when the processing fails to produce the at least one boundary delineated image, segmenting and encoding one of the at least one boundary delineated image or the boundary delineated image to generate at least one iris template, matching the at least one iris template against an enrolled iris, and accepting the subject for access processing when the at least one iris template matches the enrolled iris.

Abstract: Provided herein are resonance-enabled machines, comprising one or more voice coil actuators mounted on a non-moving mass, such as a housing, one or more moving masses, and one or more pluralities of springs coupling the non-moving mass to the one or more moving masses. One or more of the moving masses can perform a specific task. For example, the moving mass may drive a pump as a vacuum pump or a compressor. The moving mass may drive a hammer chisel, for example, to break or fracture structures. The moving mass may drive a device to consolidate, for example, soil. The moving mass may impact a member to drive the member into another member, such as a pile into the soil. Each moving mass may be coupled to a voice coil actuator, and the machine is an electrical-mechanical-electrical transformer.

Abstract: A method of producing an integrated circuit-type active radioisotope battery, the method comprising exposing at least a portion of an electronically functional, unactivated integrated circuit-type battery to radiation to convert transmutable material in the unactivated battery to a radioisotope thereby producing an active cell and thus the integrated circuit-type active radioisotope battery.

Abstract: A space vehicle may have a modular board configuration that commonly uses some or all components and a common operating system for at least some of the boards. Each modular board may have its own dedicated processing, and processing loads may be distributed. The space vehicle may be reprogrammable, and may be launched without code that enables all functionality and/or components. Code errors may be detected and the space vehicle may be reset to a working code version to prevent system failure.

Abstract: A storage vessel assembly for storing chemical includes a storage vessel, a frame for housing the storage vessel, an agitation device disposed in the storage vessel, a temperature control system coupled to the storage vessel, and a controller configured to operate the agitation device and the temperature control system.

Abstract: A field unit and ground station may use commercial off-the-shelf (COTS) components and share a common architecture, where differences in functionality are governed by software. The field units and ground stations may be easy to deploy, relatively inexpensive, and be relatively easy to operate. A novel file system may be used where datagrams of a file may be stored across multiple drives and/or devices. The datagrams may be received out of order and reassembled at the receiving device.

Abstract: A space vehicle may have a modular board configuration that commonly uses some or all components and a common operating system for at least some of the boards. Each modular board may have its own dedicated processing, and processing loads may be distributed. The space vehicle may be reprogrammable, and may be launched without code that enables all functionality and/or components. Code errors may be detected and the space vehicle may be reset to a working code version to prevent system failure.

Abstract: A method of producing an integrated circuit-type active radioisotope battery, the method comprising exposing at least a portion of an electronically functional, unactivated integrated circuit-type battery to radiation to convert transmutable material in the unactivated battery to a radioisotope thereby producing an active cell and thus the integrated circuit-type active radioisotope battery.

Abstract: A field unit and ground station may use commercial off-the-shelf (COTS) components and share a common architecture, where differences in functionality are governed by software. The field units and ground stations may be easy to deploy, relatively inexpensive, and be relatively easy to operate. A novel file system may be used where datagrams of a file may be stored across multiple drives and/or devices. The datagrams may be received out of order and reassembled at the receiving device.

Abstract: A field unit and ground station may use commercial off-the-shelf (COTS) components and share a common architecture, where differences in functionality are governed by software. The field units and ground stations may be easy to deploy, relatively inexpensive, and be relatively easy to operate. A novel file system may be used where datagrams of a file may be stored across multiple drives and/or devices. The datagrams may be received out of order and reassembled at the receiving device.

Abstract: A space vehicle may have a modular board configuration that commonly uses some or all components and a common operating system for at least some of the boards. Each modular board may have its own dedicated processing, and processing loads may be distributed. The space vehicle may be reprogrammable, and may be launched without code that enables all functionality and/or components. Code errors may be detected and the space vehicle may be reset to a working code version to prevent system failure.

Abstract: An axle bearing suspension system and method has a pair of elongated beams having an upper section and lower section with T-shaped cross sections. The T-shaped cross sections are welded together to form beams having an I-beam cross section. The beams have attachment portions which are preferably arc shaped cylindrical portions for fixing the beams to the axle with the upper section being welded to an upper part of the axle and the lower section being welded to a lower part of the axle.

Abstract: An axle bearing suspension system and method has a pair of elongated beams having an upper section and lower section with T-shaped cross sections. The T-shaped cross sections are welded together to form beams having an I-beam cross section. The beams have attachment portions which are preferably arc shaped cylindrical portions for fixing the beams to the axle with the upper section being welded to an upper part of the axle and the lower section being welded to a lower part of the axle.

Abstract: A rules system for creating rules to an expert system is provided, the rules system providing a user-friendly, guided process for creating such rules.

Abstract: A method for forming a plate-mat bag using a form, fill, and seal machine and the resultant bag. The film used to form the bag is oriented so that the product side layer is not a critical barrier layer. The top most portion of the bag is unsealed forming a tab. Below the top most portion, a peelable upper seal is utilized so that a consumer can destroy the upper seal using the tab and tear open the bag along slits made in the product side layer. This results in an easy open package which when opened can serve as a plate.

Abstract: A rules system for creating rules to an expert system is provided, the rules system providing a user-friendly, guided process for creating such rules.

Abstract: The presently disclosed subject matter generally relates to a method for detectably labeling ribonucleic acid molecules expressed in cells of interest. Also provided are methods for isolating ribonucleic acid molecules derived from genes that are expressed in cells of interest.

Abstract: A method is provided of forming a multi-pack container assembly having at least two containers joined together by a channel. The method includes the steps of providing sheet having a barrier layer thermoforming the sheet into a multi-pack container assembly having a plurality of containers wherein each container comprises a flange and the flanges of adjacent containers are connected by an engineered area of weakness or channel. Resultant containers can be used for low-moisture, shelf-stable, ready-to-eat food products.