Abstract: A bush assembly comprising a component having a bore, a bush fitted in the bore and having a flange that extends radially outwardly over a surface of the component surrounding the bore, and a seal assembly for sealing the interface between the flange and the surface of the component, wherein the seal assembly includes a seal member and a layer of sealant between the seal member and the interface between the flange and the surface of the component. Also a method for sealing a bush, a kit of parts for forming a bush assembly, and a clamping tool for forming a bush assembly.

Abstract: A glazing unit is provided in which a two part bush is provided such that relative movement between a fastener, a glazing component and a wing skin is permitted, thus avoiding stress concentrations and lowering risk of damage in use.

Abstract: A bush assembly comprising a component having a bore, a bush fitted in the bore and having a flange that extends radially outwardly over a surface of the component surrounding the bore, and a seal assembly for sealing the interface between the flange and the surface of the component, wherein the seal assembly includes a seal member and a layer of sealant between the seal member and the interface between the flange and the surface of the component. Also a method for sealing a bush, a kit of parts for forming a bush assembly, and a clamping tool for forming a bush assembly.

Abstract: Disclosed are methods for treating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis, Alzheimer's Disease Parkinson's Disease, Myasthenia Gravis, Multifocal Motor Neuropathy, Primary Lateral Sclerosis, Spinal Muscular Atrophy, Kennedy's Disease, and Spinocerebellar Ataxia.

Abstract: A bush assembly comprising a component having a bore, a bush fitted in the bore and having a flange that extends radially outwardly over a surface of the component surrounding the bore, and a seal assembly for sealing the interface between the flange and the surface of the component, wherein the seal assembly includes a seal member and a layer of sealant between the seal member and the interface between the flange and the surface of the component. Also a method for sealing a bush, a kit of parts for forming a bush assembly, and a clamping tool for forming a bush assembly.

Abstract: Disclosed are methods for treating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Parkinson's Disease, Myasthenia Gravis, Multifocal Motor Neuropathy, Primary Lateral Sclerosis, Spinal Muscular Atrophy, Kennedy's Disease, and Spinocerebellar Ataxia, by administration of a compound that blocks the interaction of CD40 and CD40L.

Abstract: A glazing unit is provided in which a two part bush is provided such that relative movement between a fastener, a glazing component and a wing skin is permitted, thus avoiding stress concentrations and lowering risk of damage in use.

Abstract: The present invention relates to a process of preparing a compound of the following formula III: wherein R1-R4 are as defined herein. The present invention also relates to the preparation of intermediates used to prepare the compound of formula III.

Abstract: Disclosed are methods for treating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Parkinson's Disease, Myasthenia Gravis, Multifocal Motor Neuropathy, Primary Lateral Sclerosis, Spinal Muscular Atrophy, Kennedy's Disease, and Spinocerebellar Ataxia, by administration of a compound that blocks the interaction of CD40 and CD40L.

Abstract: The invention relates to the use of magnesium stearate to inhibit or reduce chemical degradation of an active ingredient substance in a formulation comprising a carrier in a solid pharmaceutical formulation, wherein the active ingredient substance is susceptible to chemical degradation.

Abstract: The present invention relates to a process of preparing a compound of the following formula III: wherein R1-R4 are as defined herein.

Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.

Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.

Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.

Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.

Abstract: A cross joint (10) is shown that has been formed from a single, flat folded and partially cut sheet. Base panels (12) to (26) are caused to lie horizontally at the base of the joint with the innermost portion of the panel (14) overlapping the innermost portion of the panel (26) and so on around the joint. Panels (34) to (48) extend vertically with panels that include a common fold lying alongside each other and in contact with each other. Panels (56) to (70) lie horizontally at the top with the panel (58) overlapping completely the panel (70) and so on around the structure.

Abstract: There is disclosed a portable printer and a method of selectively printing on any one of a plurality of label rolls housed in the printer, or on a wide roll housed in the printer.

Abstract: The present invention relates to novel compounds of formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.