Abstract: The instant disclosure provides antibodies that specifically bind to T-cell immunoreceptor with Ig and ITIM domains (TIGIT) (e.g., human TIGIT) and antagonize TIGIT function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: A golf club head including a striking face, a periphery portion surrounding and extending rearwards from the striking face, a damping element including a front surface and a rear surface, the rear surface of the damping element opposite the front surface of the damping element, wherein the striking face comprises a first portion having a substantially constant thickness, wherein the front surface of the damping element comprises a geometric center, wherein the striking face comprises a second portion, the second portion of the striking face located heelward of the center face plane, the second portion of the striking face having a thickness which tapers from a maximum thickness at a thick end of the second portion to a minimum thickness at a thin end of the second portion, wherein the thick end is located toeward of the thin end.

Abstract: A golf club head including a striking face; a periphery portion surrounding and extending rearwards from the striking face; wherein the striking face comprises a front surface configured to strike a golf ball and a rear surface opposite the front surface; a support arm spaced from the rear surface of the striking face; wherein the support arm abuts the periphery portion at two distinct locations; a damping element residing between the support arm and the rear surface of the striking face; wherein the damping element comprises a front surface in contact with the rear surface of the striking face and a rear surface in contact with the support arm.

Abstract: Provided herein are antibodies that are useful for treating SARS-CoV-2 infections in a subject. Also provided herein are compositions comprising one or more antibodies, methods of treatment comprising administering one or more antibodies, and kits comprising one or more antibodies.

Abstract: An earth-boring tool may include a blade having a face surface, a cutting edge, and a rotationally leading surface. The earth-boring tool may additionally include at least one fluid port extending through the blade, and a fluid port manifold having an opening at a first end and a plurality of openings along a length providing fluid communication between the at least one fluid port and a primary fluid passage of the earth-boring tool. An additional earth-boring tool may include a fluid port manifold located in the tool body and a plurality of fluid port sleeves, each fluid port sleeve of the plurality of fluid port sleeves extending into a corresponding opening of a plurality of openings along the length of the fluid port manifold.

Abstract: A golf club head including a striking face, a periphery portion, and a support arm spaced from the rear surface of the striking face, a first damping element residing between the support arm and the rear surface of the striking face, wherein the first damping element comprises a front surface in contact with the rear surface of the striking face and a rear surface in contact with the support arm, wherein the periphery portion comprises a sole, and a second damping element located between the first damping element and the sole, a front portion of the second damping element in contact with the rear surface of the striking face, a rear surface of the second damping element in contact with the support arm.

Abstract: A golf club head including a club head body comprising a back portion, a striking face, and an interior cavity formed between the back portion and the striking face, wherein the striking face includes a front surface configured to strike a golf ball and a rear surface opposite the front surface, a deformable member residing between the back portion and the rear surface of the striking face, wherein the deformable member includes a front surface in contact with the rear surface of the striking face, wherein the deformable member includes a rear surface in contact with the back portion, wherein the deformable member includes a free thickness and an installed thickness, and wherein the free thickness is at least 5% greater than the installed thickness.

Abstract: A golf club head including a striking face, a periphery portion surrounding and extending rearwards from the striking face, wherein the striking face comprises a front surface configured to strike a golf ball and a rear surface opposite the front surface, a support arm spaced from the rear surface of the striking face, the support arm extending from the periphery portion, wherein the support arm is affixed to the periphery portion at two distinct locations, a damping element residing between the support arm and the rear surface of the striking face, wherein the damping element comprises a front surface in contact with the rear surface of the striking face and a rear surface in contact with the support arm, wherein the support arm extends substantially parallel a horizontal axis.

Abstract: Provided herein are antibodies that are useful for treating SARS-CoV-2 infections in a subject. Also provided herein are compositions comprising one or more antibodies, methods of treatment comprising administering one or more antibodies, and kits comprising one or more antibodies.

Abstract: A golf club head including a striking face; a periphery portion surrounding and extending rearwards from the striking face; wherein the striking face comprises a front surface configured to strike a golf ball and a rear surface opposite the front surface; a support arm spaced from the rear surface of the striking face; wherein the support arm abuts the periphery portion at two distinct locations; a damping element residing between the support arm and the rear surface of the striking face; wherein the damping element comprises a front surface in contact with the rear surface of the striking face and a rear surface in contact with the support arm.

Abstract: A golf club head including a striking face, a periphery portion, and a support arm spaced from the rear surface of the striking face, a first damping element residing between the support arm and the rear surface of the striking face, wherein the first damping element comprises a front surface in contact with the rear surface of the striking face and a rear surface in contact with the support arm, wherein the periphery portion comprises a sole, and a second damping element located between the first damping element and the sole, a front portion of the second damping element in contact with the rear surface of the striking face, a rear surface of the second damping element in contact with the support arm.

Abstract: A golf club head including a club head body comprising a back portion, a striking face, and an interior cavity formed between the back portion and the striking face, wherein the striking face includes a front surface configured to strike a golf ball and a rear surface opposite the front surface, a deformable member residing between the back portion and the rear surface of the striking face, wherein the deformable member includes a front surface in contact with the rear surface of the striking face, wherein the deformable member includes a rear surface in contact with the back portion, wherein the deformable member includes a free thickness and an installed thickness, and wherein the free thickness is at least 5% greater than the installed thickness.

Abstract: A golf club head including a striking face, a periphery portion surrounding and extending rearwards from the striking face, wherein the striking face comprises a front surface configured to strike a golf ball and a rear surface opposite the front surface, a support arm spaced from the rear surface of the striking face, the support arm extending from the periphery portion, wherein the support arm is affixed to the periphery portion at two distinct locations, a damping element residing between the support arm and the rear surface of the striking face, wherein the damping element comprises a front surface in contact with the rear surface of the striking face and a rear surface in contact with the support arm, wherein the support arm extends substantially parallel a horizontal axis.

Abstract: An elastic nonwoven material includes a first non-woven fabric including a plurality of rows. Each row has a plurality of adjacent bonds formed therein. The elastic nonwoven material also includes a first elastic strand entrapped between a first pair of adjacent bonds within a first row of the plurality of rows, and a second elastic strand entrapped between a second pair of adjacent bonds within the first row. A third pair of adjacent bonds within the first row is free of elastic material therebetween and is located between the first pair of adjacent bonds and the second pair of adjacent bonds.

Abstract: A crimping tool for crimping a metallic crimp ring. The crimping tool includes a first crimp die having a first curved contact surface and a second curved contact surface, the second curved contact surface spaced apart from the first curved contact surface, and a trench extending between the first curved contact surface and the second curved contact surface. The crimping tool also includes a second crimp die cooperatively engageable with the first crimp die having a first curved contact surface and a second curved contact surface, the second curved contact surface spaced apart from the first curved contact surface, and a trench extending between the first curved contact surface and the second curved contact surface. The trench of the first crimp die and the trench of the second crimp die forms an annular bead in a center portion of the metallic crimp ring.

Abstract: A crimping tool for crimping a metallic crimp ring. The crimping tool includes a first crimp die having a first curved contact surface and a second curved contact surface, the second curved contact surface spaced apart from the first curved contact surface, and a trench extending between the first curved contact surface and the second curved contact surface. The crimping tool also includes a second crimp die cooperatively engageable with the first crimp die having a first curved contact surface and a second curved contact surface, the second curved contact surface spaced apart from the first curved contact surface, and a trench extending between the first curved contact surface and the second curved contact surface. The trench of the first crimp die and the trench of the second crimp die forms an annular bead in a center portion of the metallic crimp ring.

Abstract: A golf club head including a striking face, a periphery portion surrounding and extending rearwards from the striking face, a damping element including a front surface and a rear surface, the rear surface of the damping element opposite the front surface of the damping element, wherein the striking face comprises a first portion having a substantially constant thickness, wherein the front surface of the damping element comprises a geometric center, wherein the striking face comprises a second portion, the second portion of the striking face located heelward of the center face plane, the second portion of the striking face having a thickness which tapers from a maximum thickness at a thick end of the second portion to a minimum thickness at a thin end of the second portion, wherein the thick end is located toeward of the thin end.

Abstract: An earth-boring tool may include a blade having a face surface, a cutting edge, and a rotationally leading surface. The earth-boring tool may additionally include at least one fluid port extending through the blade, and a fluid port manifold having an opening at a first end and a plurality of openings along a length providing fluid communication between the at least one fluid port and a primary fluid passage of the earth-boring tool. An additional earth-boring tool may include a fluid port manifold located in the tool body and a plurality of fluid port sleeves, each fluid port sleeve of the plurality of fluid port sleeves extending into a corresponding opening of a plurality of openings along the length of the fluid port manifold.

Abstract: An earth-boring tool may include at least one blade including a shoulder region and a face. A plurality of cutting elements may be arranged on the face of the blade and at least one cutting element may be positioned in the shoulder region such that a cutting face of the at least one cutting element is spaced a distance behind the face of the blade. A recessed portion of the blade may extend under at least one of the plurality of cutting elements arranged on the face of the blade and extending to the at least one cutting element positioned in the shoulder region.

Abstract: An elastic nonwoven material includes a first non-woven fabric including a plurality of rows. Each row has a plurality of adjacent bonds formed therein. The elastic nonwoven material also includes a first elastic strand entrapped between a first pair of adjacent bonds within a first row of the plurality of rows, and a second elastic strand entrapped between a second pair of adjacent bonds within the first row. A third pair of adjacent bonds within the first row is free of elastic material therebetween and is located between the first pair of adjacent bonds and the second pair of adjacent bonds.