Abstract: A method may include receiving measurements of drilling fluid properties of drilling fluid during drilling indicative of a current drilling fluid condition; automatically determining a forecast drilling fluid condition based on the measurements using a model-based computational framework; analyzing the current drilling fluid condition and the future drilling condition; based on the analyzing, automatically generating a treatment recommendation and an associated projected drilling fluid condition based on the measurements using the model-based computational framework; responsive to implementation of the treatment recommendation, receiving additional measurements of the drilling fluid properties indicative of an actual drilling fluid condition; and, based at least in part on a comparison of projected drilling fluid condition and the actual drilling fluid condition, generating a quality indicator of the treatment recommendation.

Abstract: A method may include receiving data acquired during one or more well construction operations; detecting one or more fluid states using a number of predefined fluid states and the data, where the predefined fluid states include operational fluid states and associated fluid sub-states; generating, using the one or more fluid states, an assessment of a fluid treatment; and outputting the assessment of the fluid treatment.

Abstract: Methods and systems are provided that determine at least one fluid parameter for a drilling fluid and a particular drilling operation, wherein the at least one fluid parameter is selected from the group consisting of: i) a first fluid parameter that relates to shear forces that break apart components of the drilling fluid during the particular drilling operation, ii) a second fluid parameter that characterizes mixing of drill cuttings with the drilling fluid during the particular drilling operation, and iii) third and fourth fluid parameters that characterize normal stress in the drilling fluid during the drilling operation. The methods and systems can evaluate one or more of these fluid parameters to determine a drilling fluid formulation that optimizes the drilling fluid for effective transport of drill cuttings.

Abstract: Devices and methods to perform AC impedance measurement of a device which use an excitation signal including a root mean squared current or a root mean squared voltage in a sequence of one or more frequency groups, wherein each of said frequency groups includes a summation of one or more frequencies within a frequency spread.

Abstract: An synthetic fiber oral flavored product includes a fibrous substrate. The fibrous substrate is made of a synthetic polyester in a typically pelletized shape imbued a carrier liquid of propylene glycol or equivalent. The carrier liquid carries a freebase synthetic nicotine, a binding agent, a textural adjustment agent and flavorants. In some examples, the fibrous substrate is heat treated and modified by heating and rapid cooling the substrate to increase the zeta potential of the fibrous substrate.

Abstract: Devices and methods to perform AC impedance measurement of a device which use an excitation signal including a root mean squared current or a root mean squared voltage in a sequence of one or more frequency groups, wherein each of said frequency groups includes a summation of one or more frequencies within a frequency spread.

Abstract: The present invention relates to an aminosquaramide polymer comprising a backbone of repeating structural units, being these repeating structural units equal or different and selected from the group consisting of: monomer of formula (A) (or a salt thereof), and monomer of formula (B) (or a salt thereof); and a conjugate comprising the aminosquaramide polymer and one or more molecules of interest. It also refers to compositions containing the polymer or the conjugate; and processes for their preparation, as well as their uses as a carrier, in therapy, in diagnostic, in cosmetic and as a transfecting agent.

Abstract: In a general aspect, a quantum processor has a modular architecture. In some aspects, a modular quantum processor includes first and second quantum processor chips and a cap structure. The first quantum processor chip is supported on a substrate layer and includes a first plurality of qubit devices. The second quantum processor chip is supported on the substrate layer and includes a second plurality of qubit devices. The cap structure is supported on the first and second quantum processor chips and includes a coupler device that provides coupling between at least one of the first plurality of qubit devices with at least one of the second plurality of qubit devices. In some instances, the coupler device is an active coupler device that is configured to selectively couple at least one of the first plurality of qubit devices with at least one of the second plurality of qubit devices.

Abstract: Impedance testing devices, circuits, systems, and related methods are disclosed. A Device Under Test (DUT) is excited with a multispectral excitation signal for an excitation time period while the DUT is under a load condition from a load operably coupled to the DUT. A response of the DUT is sampled over a sample time period. The sample time period is configured such that it includes an in-band interval during the excitation time period and one or more out-of-band intervals outside of the in-band interval. A response of the DUT to the load condition during the in-band interval is estimated by analyzing samples of the response from the one or more out-of-band intervals. Adjusted samples are computed by subtracting the estimated load response during the in-band interval from the samples from the in-band interval. An impedance of the DUT is estimated by analyzing the adjusted samples.

Abstract: A downhole wellbore planner builds a fracture model of a wellbore using fracture data identified from geological information. Using the fracture model and a target wellbore location at the formation, the wellbore planner may identify or select one or more lost circulation materials (LCMs). The drilling operator may then procure the LCMs before drilling the wellbore. In this manner, the impact of a lost circulation event may be reduced by having the LCMs on site or nearby.

Abstract: Liquid formulations for use in an oral product include about 85% w/w to about 95% w/w of a carrier liquid; about 1% w/w to about 5% w/w of a flavoring agent; about 1% w/w to about 2% w/w of an active ingredient; and about 0.5% w/w to about 3.5% w/w of a sweetener. Oral products are further provided and comprise about 25% w/w to about 30% w/w of a fibrous substrate; about 50% w/w to about 70% w/w of a carrier liquid; about 1% w/w to about 5% w/w of a flavoring agent; about 0.5% w/w to about 2% w/w of an active ingredient; and about 0.1% w/w to about 3.5% w/w of a sweetener. Methods of making an oral product are also provided and comprise the steps of providing an exemplary liquid formulation, and then combining the liquid formulation with a fibrous substrate.

Abstract: A drilling fluid manager receives measurements of drilling fluid data over a period of time. The drilling fluid manager analyzes the time-series drilling fluid data to diagnose a contaminant type, contaminant concentration, and a rate of change of contaminant concentration. The drilling fluid manager develops a treatment plan with a treatment type, a treatment mass, and a treatment schedule for the contaminant type.

Abstract: A downhole wellbore planner builds a fracture model of a wellbore using fracture data identified from geological information. Using the fracture model and a target wellbore location at the formation, the wellbore planner may identify or select one or more lost circulation materials (LCMs). The drilling operator may then procure the LCMs before drilling the wellbore. In this manner, the impact of a lost circulation event may be reduced by having the LCMs on site or nearby.

Abstract: Devices and methods to perform AC impedance measurement of a device which use an excitation signal including a root mean squared current or a root mean squared voltage in a sequence of one or more frequency groups, wherein each of said frequency groups includes a summation of one or more frequencies within a frequency spread.

Abstract: The present disclosure provides methods for treating sarcoidosis-associated pulmonary hypertension, comprising administering to a patient in need thereof, a therapeutically effective amount of selexipag, wherein the patient is diagnosed with sarcoidosis-associated pulmonary hypertension.

Abstract: A canopy for varying the height of a lighting fixture suspended from a ceiling or elevated support structure via the cable/cord supplying power to the lighting fixture. The canopy has a notched spool mounted non-rotatably to the ceiling or elevated support structure. The spool has a core part around which the power cable/cord is wrapped to change the effective length of cable/cord. A revolving hook bolt is connected to the spool such that the bolt can be rotated to face a notch through which the cable/cord has been inserted. The hook bolt has a rounded edge bump that the cable/cord passes through after exiting the notch. The edge bump is configured to securely retain the cable in a fixed position without slippage and to support the weight of the suspended lighting fixture in a secure slip-free manner.

Abstract: Impedance testing devices, circuits, systems, and related methods are disclosed. A Device Under Test (DUT) is excited with a multispectral excitation signal for an excitation time period while the DUT is under a load condition from a load operably coupled to the DUT. A response of the DUT is sampled over a sample time period. The sample time period is configured such that it includes an in-band interval during the excitation time period and one or more out-of-band intervals outside of the in-band interval. A response of the DUT to the load condition during the in-band interval is estimated by analyzing samples of the response from the one or more out-of-band intervals. Adjusted samples are computed by subtracting the estimated load response during the in-band interval from the samples from the in-band interval. An impedance of the DUT is estimated by analyzing the adjusted samples.

Abstract: A surface rig system includes components that consume power (e.g., using electrical motors). The power consumption of the components is monitored and used to infer other operational parameters. Illustratively, power consumption (e.g., current draw) of a shale shaker is monitored and used to infer: the volume of cuttings on the screen; changes in fluid viscosity, density, or rheology; health of the shaker screen; fluid cycle times; or screen clogging/blinding. Power consumption of pumps, fluid agitators, draw works, and other devices can also be monitored and used to infer parameters such as: fluid viscosity, density or rheology; hook load, or fluid slugging. Based on inferred parameters, changes may be made or advised for operation of equipment, including a shale shaker, downhole tool, pump, shaker screen, top drive, drilling fluid, or draw works.

Abstract: In a general aspect, a quantum processor has a modular architecture. In some aspects, a modular quantum processor includes first and second quantum processor chips and a cap structure. The first quantum processor chip is supported on a substrate layer and includes a first plurality of qubit devices. The second quantum processor chip is supported on the substrate layer and includes a second plurality of qubit devices. The cap structure is supported on the first and second quantum processor chips and includes a coupler device that provides coupling between at least one of the first plurality of qubit devices with at least one of the second plurality of qubit devices. In some instances, the coupler device is an active coupler device that is configured to selectively couple at least one of the first plurality of qubit devices with at least one of the second plurality of qubit devices.

Abstract: The present invention provides a method for manufacturing a finished metal object or product having a corrosion resistant layer integral to or within a top portion of at least one of its surfaces that would be exposed to a corrosive environment. In one embodiment, the method for manufacturing is directed to a finished metal tubing product having a corrosion resistant layer within its inside surface that is exposed to a fluid and wherein the corrosion resistant layer is a zinc-metal oxide layer, such as a zinc-chromium oxide layer, or a zinc-mixed metal oxide layer. In addition to methods of manufacturing, the present invention provides finished metal objects or products having a corrosion resistant layer integral to or within a top portion of at least one surfaces that would be exposed to a corrosive environment.