Abstract: A swept-source optical coherence tomography (SS-OCT) apparatus includes a plurality of wavelength-tunable light sources. The SS-OCT apparatus includes a first optical coupler configured to receive an output from each of the plurality of wavelength-tunable light sources. The optical coupler is configured to split the received output from the plurality of wavelength-tunable light sources into a reference optical path and a sample optical path. The sample optical path is configured to illuminate a sample. The SS-OCT apparatus includes a second optical coupler configured to receive return optical signals from the reference optical path and the sample optical path, and to output an optical interference signal. The SS-OCT apparatus includes a detector configured to detect the optical interference signal; and a controller configured to receive an electrical signal based on the detected optical interference signal. The controller is configured to generate a depth profile of the sample using compressed sensing.

Abstract: Purine derivatives are provided for treatment of cellular stress, particularly hypoxia. By administering the purine derivatives by themselves or in conjunction with other compounds, particularly electron acceptor compounds and/or amino acids, the time for irreversible cellular changes, particularly mortality, can be greatly extended.