Patents by Inventor John NGO

John NGO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION
    Publication number: 20250243247
    Abstract: The technology described herein is directed to CAR polypeptides and systems comprising repressible proteases. In combination with a specific protease inhibitor, the activity of said CAR polypeptides and systems and cells comprising them can be modulated. Also described herein are methods of using said CAR polypeptides and systems, for example to treat various diseases and disorders.
    Type: Application
    Filed: December 12, 2024
    Publication date: July 31, 2025
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: John NGO, Wilson WONG, Meng Lai Nicole WONG, Huishan LI, Elliot P. TAGUE
  • Chimeric antigen receptor (CAR) modulation
    Patent number: 12202863
    Abstract: The technology described herein is directed to CAR polypeptides and systems comprising repressible proteases. In combination with a specific protease inhibitor, the activity of said CAR polypeptides and systems and cells comprising them can be modulated. Also described herein are methods of using said CAR polypeptides and systems, for example to treat various diseases and disorders.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: January 21, 2025
    Assignee: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: John Ngo, Wilson Wong, Meng Lai Nicole Wong, Huishan Li, Elliot P. Tague
  • CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION
    Publication number: 20220098246
    Abstract: The technology described herein is directed to CAR polypeptides and systems comprising repressible proteases. In combination with a specific protease inhibitor, the activity of said CAR polypeptides and systems and cells comprising them can be modulated. Also described herein are methods of using said CAR polypeptides and systems, for example to treat various diseases and disorders.
    Type: Application
    Filed: June 9, 2021
    Publication date: March 31, 2022
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: John NGO, Wilson WONG, Meng Lai Nicole WONG, Huishan LI, Elliot P. TAGUE
  • Chimeric antigen receptor (CAR) modulation
    Patent number: 11059864
    Abstract: The technology described herein is directed to CAR polypeptides and systems comprising repressible proteases. In combination with a specific protease inhibitor, the activity of said CAR polypeptides and systems and cells comprising them can be modulated. Also described herein are methods of using said CAR polypeptides and systems, for example to treat various diseases and disorders.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: July 13, 2021
    Assignee: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: John Ngo, Wilson Wong, Meng Lai Nicole Wong, Huishan Li, Elliot P. Tague
  • Inducible Cell Receptors for Cell-Based Therapeutics
    Publication number: 20210189367
    Abstract: The present disclosure provides inducible cell receptors and therapeutic cells comprising the inducible cell receptors. Further provided are methods of preparing the therapeutic cells and methods of treating a subject by administering the therapeutic cells and regulating activity of (e.g. activating and/or inactivating) the cell receptors.
    Type: Application
    Filed: December 11, 2018
    Publication date: June 24, 2021
    Inventors: Philip Janmin Lee, Timothy Kuan-ta Lu, Russell Morrison Gordley, Wilson Wong, John Ngo
  • CHIMERIC ANTIGEN RECEPTOR (CAR) MODULATION
    Publication number: 20200308234
    Abstract: The technology described herein is directed to CAR polypeptides and systems comprising repressible proteases. In combination with a specific protease inhibitor, the activity of said CAR polypeptides and systems and cells comprising them can be modulated. Also described herein are methods of using said CAR polypeptides and systems, for example to treat various diseases and disorders.
    Type: Application
    Filed: March 27, 2020
    Publication date: October 1, 2020
    Applicant: TRUSTEES OF BOSTON UNIVERSITY
    Inventors: John NGO, Wilson WONG, Meng Lai Nicole WONG, Huishan LI, Elliot P. TAGUE