Patents by Inventor John Niu

John Niu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12269807
    Abstract: The invention relates to crystalline forms of the bis-HCl salt of a compound represented by Structural Formula 1, and pharmaceutical compositions comprising crystalline forms of the bis-HCL salt of a compound represented by Structural Formula 1 described herein. The crystalline forms of the bis-HCl salt of a compound of Structural Formula 1 and compositions comprising the crystalline forms of the compound of Structural Formula 1 provided herein, in particular, crystalline Form I, crystalline Form J, crystalline Form A, and crystalline Form B, or mixtures thereof, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders. Also described herein are methods for preparing the crystalline forms (e.g., Forms I, J, B and A) of the bis-HCl salt of a compound represented by Structural Formula 1.
    Type: Grant
    Filed: January 5, 2023
    Date of Patent: April 8, 2025
    Assignee: Tetraphase Pharmaceuticals, Inc.
    Inventors: Danny LaFrance, Philip C. Hogan, Yansheng Liu, Minsheng He, Chi-Li Chen, John Niu
  • Publication number: 20230416212
    Abstract: The invention relates to crystalline forms of the bis-HCl salt of a compound represented by Structural Formula 1, and pharmaceutical compositions comprising crystalline forms of the bis-HCL salt of a compound represented by Structural Formula 1 described herein. The crystalline forms of the bis-HCl salt of a compound of Structural Formula 1 and compositions comprising the crystalline forms of the compound of Structural Formula 1 provided herein, in particular, crystalline Form I, crystalline Form J, crystalline Form A, and crystalline Form B, or mixtures thereof, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders. Also described herein are methods for preparing the crystalline forms (e.g., Forms I, J, B and A) of the bis-HCl salt of a compound represented by Structural Formula 1.
    Type: Application
    Filed: January 5, 2023
    Publication date: December 28, 2023
    Inventors: Danny Lafrance, Philip C. Hogan, Yansheng Liu, Minsheng He, Chi-Li Chen, John Niu
  • Patent number: 11578044
    Abstract: The invention relates to crystalline forms of the bis-HCl salt of a compound represented by Structural Formula 1, and pharmaceutical compositions comprising crystalline forms of the bis-HCL salt of a compound represented by Structural Formula 1 described herein. The crystalline forms of the bis-HCl salt of a compound of Structural Formula 1 and compositions comprising the crystalline forms of the compound of Structural Formula 1 provided herein, in particular, crystalline Form I, crystalline Form J, crystalline Form A, and crystalline Form B, or mixtures thereof, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders. Also described herein are methods for preparing the crystalline forms (e.g., Forms I, J, B and A) of the bis-HCl salt of a compound represented by Structural Formula 1.
    Type: Grant
    Filed: March 1, 2021
    Date of Patent: February 14, 2023
    Assignee: Tetraphase Pharmaceuticals, Inc.
    Inventors: Danny LaFrance, Philip C. Hogan, Yansheng Liu, Minsheng He, Chi-Li Chen, John Niu
  • Publication number: 20210363103
    Abstract: The invention relates to crystalline forms of the bis-HCl salt of a compound represented by Structural Formula 1, and pharmaceutical compositions comprising crystalline forms of the bis-HCL salt of a compound represented by Structural Formula 1 described herein. The crystalline forms of the bis-HCl salt of a compound of Structural Formula 1 and compositions comprising the crystalline forms of the compound of Structural Formula 1 provided herein, in particular, crystalline Form I, crystalline Form J, crystalline Form A, and crystalline Form B, or mixtures thereof, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders. Also described herein are methods for preparing the crystalline forms (e.g., Forms I, J, B and A) of the bis-HCl salt of a compound represented by Structural Formula 1.
    Type: Application
    Filed: March 1, 2021
    Publication date: November 25, 2021
    Inventors: Danny Lafrance, Philip C. Hogan, Yansheng Liu, Minsheng He, Chi-Li Chen, John Niu
  • Patent number: 10961190
    Abstract: The invention relates to crystalline forms of the bis-HCI salt of a compound represented by Structural Formula 1, and pharmaceutical compositions comprising crystalline forms of the bis-HCL salt of a compound represented by Structural Formula 1 described herein. The crystalline forms of the bis-HCl salt of a compound of Structural Formula 1 and compositions comprising the crystalline forms of the compound of Structural Formula 1 provided herein, in particular, crystalline Form I, crystalline Form J, crystalline Form A, and crystalline Form B, or mixtures thereof, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders. Also described herein are methods for preparing the crystalline forms (e.g., Forms I, J, B and A) of the bis-HCI salt of a compound represented by Structural Formula 1.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: March 30, 2021
    Assignee: Tetraphase Pharmaceuticals, Inc.
    Inventors: Danny LaFrance, Philip C. Hogan, Yansheng Liu, Minsheng He, Chi-Li Chen, John Niu
  • Publication number: 20190256462
    Abstract: The invention relates to crystalline forms of the bis-HCI salt of a compound represented by Structural Formula 1, and pharmaceutical compositions comprising crystalline forms of the bis-HCL salt of a compound represented by Structural Formula 1 described herein. The crystalline forms of the bis-HCl salt of a compound of Structural Formula 1 and compositions comprising the crystalline forms of the compound of Structural Formula 1 provided herein, in particular, crystalline Form I, crystalline Form J, crystalline Form A, and crystalline Form B, or mixtures thereof, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders. Also described herein are methods for preparing the crystalline forms (e.g., Forms I, J, B and A) of the bis-HCI salt of a compound represented by Structural Formula 1.
    Type: Application
    Filed: October 19, 2017
    Publication date: August 22, 2019
    Inventors: Danny LaFrance, Philip C. Hogan, Yansheng Liu, Minsheng He, Chi-Li Chen, John Niu
  • Publication number: 20150257092
    Abstract: A method and a base station for a cell selection are provided. The method comprises obtaining an uplink traffic status of a user equipment. The method also comprises determining, based upon the plink traffic status, a bias value for a measured quality indicator of a down link received signal with respect to the user equipment. In addition, the method comprises performing the cell selection based upon the bias value and the measured quality indicator. With the present invention, a proper cell could be selected and thus both peak DL and UL throughput can be improved in the heterogeneous network.
    Type: Application
    Filed: November 7, 2012
    Publication date: September 10, 2015
    Inventors: Shuang Zhao, Yanchao John Niu, Rui Zha, Min Wen