Patents by Inventor John O'Mullane

John O'Mullane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHENYLEPHRINE PHARMACEUTICAL FORMULATIONS AND COMPOSITIONS FOR COLONIC ABOSORPTION
    Publication number: 20150290147
    Abstract: The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layer(s).
    Type: Application
    Filed: December 16, 2014
    Publication date: October 15, 2015
    Applicant: MSD Consumer Care, Inc.
    Inventors: David Monteith, John O'Mullane, Robert T. Nowak, Jiansheng Wan, Mohammed A. Kabir, Joseph P. Reo, Malaz A. Abutarif, Glenn E. Fritz
  • Phenylephrine pharmaceutical formulations and compositions for colonic absorption
    Patent number: 8956662
    Abstract: The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layer(s).
    Type: Grant
    Filed: June 1, 2007
    Date of Patent: February 17, 2015
    Assignee: MSD Consumer Care, Inc.
    Inventors: David Monteith, John O'Mullane, Joseph P. Reo, Robert T. Nowak, Jiansheng Wan, Mohammed A. Kabir, Malaz A. Abutarif, Glenn E. Fritz
  • PHENYLEPHRINE PHARMACEUTICAL FORMULATIONS AND COMPOSITIONS FOR TRANSMUCOSAL ABSORPTION
    Publication number: 20090280160
    Abstract: Pharmaceutical compositions comprising phenylephrine or a pharmaceutically acceptable salt thereof and methods for administering the pharmaceutical compositions wherein the composition is formulated for systemic absorption of phenylephrine that avoids first pass metabolism. The compositions of the invention are formulated to be applied to oral mucosa of an animal to allow for enhanced systemic delivery of therapeutically active form of phenylephrine.
    Type: Application
    Filed: December 4, 2008
    Publication date: November 12, 2009
    Inventors: David Monteith, John O'Mullane, Joseph P. Reo, Dennis Nelson, Jiansheng Wan, Xiaoming Chen, Mohammed A. Kabir
  • Phenylephrine Pharmaceutical Formulations and Compositions for Colonic Absorption
    Publication number: 20080020055
    Abstract: The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the composition delivers phenylephrine or a pharmaceutically acceptable salt thereof via absorption in the colon. The pharmaceutical composition comprises a core comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is in a time-dependent, pH-dependent, or colon-specific enzyme-dependent erodible layer that degrades to expose the core to release phenylephrine in the colon. In one preferred embodiment, the erodible layer encases the core. The composition optionally further comprises phenylephrine in the erodible layer or other additional layer(s).
    Type: Application
    Filed: June 1, 2007
    Publication date: January 24, 2008
    Inventors: David Monteith, John O'Mullane, Joseph Reo, Robert Nowak, Jiansheng Wan, Mohammed Kabir, Malaz Abutarif, Glenn Fritz