Abstract: The present disclosure provides systems and methods for processing laser speckle signals. The method may comprise obtaining a laser speckle signal from a laser speckle pattern generated using at least one laser light source that is directed towards a tissue region of a subject and a reference signal corresponding to a movement of a biological material of or within the subject's body. The method may comprise computing one or more measurements using a first function corresponding to at least the laser speckle signal and a second function corresponding to the reference signal. The method may comprise generating an output signal in part based on the one or more measurements for the function space and using the output signal to aid a surgical procedure on or near the tissue region of the subject.

Abstract: The present disclosure provides a system for medical imaging. The system may comprise one or more imaging sensors for imaging a surgical scene. Each of the one or more imaging sensors may comprise a plurality of pixels. At least one pixel of the plurality of pixels may comprise a plurality of sub-pixels sensitive to different bands or wavelengths of light. The system may further comprise a processing unit operatively coupled to the one or more imaging sensors. The processing unit may be configured to perform a quantitative analysis of one or more features or fiducials that are detectable within the surgical scene based on one or more light signals obtained or registered using the plurality of sub-pixels.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Abstract: Provided herein are systems, methods, and media capable of determining estimated force applied on a target tissue region to enable tactile feedback during interaction with said target tissue region.

Abstract: A computer-implemented method is provided for training a neural network to determine an elastic property of a target issue region. A first training set is generated to include a plurality of sets of images. Each set of images includes a first speckle image of the target issue region at rest and a second speckle image of the target issue region being deformed by a known force. The neural network is trained in a first stage using the first training set. A second training set is generated to include the first training set and one or more sets of images having an elastic property value incorrectly determined after the first stage of training. The neural network is trained in a second stage using the second training set.

Abstract: The present disclosure provides a method for quantifying perfusion. The method may comprise (a) obtaining at least one image of a surgical scene: (b) processing the at least one image to determine one or more perfusion characteristics associated with one or more reference regions in the surgical scene: and (c) determining one or more relative perfusion characteristics for a target region in the surgical scene based on the at least one image and the one or more perfusion characteristics associated with the one or more reference regions.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Abstract: A method includes, as a robot encounters an object, creating a probabilistic object model to identify, localize, and manipulate the object, the probabilistic object model using light fields to enable efficient inference for object detection and localization while incorporating information from every pixel observed from across multiple camera locations.

Abstract: The present disclosure provides methods for processing medical data. The method may comprise receiving a plurality of data inputs associated with (i) at least one medical patient or (ii) at least one surgical procedure. The method may further comprise receiving one or more annotations for at least a subset of the plurality of data inputs. The method may further comprise generating an annotated data set using (i) the one or more annotations and (ii) one or more data inputs of the plurality of data inputs. The method may further comprise using the annotated data set to (i) perform data analytics for the plurality of data inputs, (ii) develop one or more medical training tools, or (iii) train one or more medical models.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Abstract: The present disclosure provides a system for enabling autonomous or semi-autonomous surgical operations. The system comprises: one or more processors that are individually or collectively configured to: process an image data stream comprising one or more images of a surgical site; fit a parametric model to a tissue surface identified in the one or more images; determine a direction for aligning a tool based in part on the parametric model; determine an optimal path for automatically moving the tool to perform a surgical procedure at the surgical site; and generate one or more control signals for controlling i) a movement of the tool based on the optimal path and ii) a tension force applied to the tissue by the tool during the surgical procedure.

Abstract: Provided herein are systems, methods, and media capable of determining estimated force applied on a target tissue region to enable tactile feedback during interaction with said target tissue region.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise a plurality of illumination sources. The plurality of illumination sources may comprise at least two of (i) a white light source configured to generate a white light beam and (ii) one or more light emitting diodes (LEDs) or laser light sources configured to generate one or more laser light beams. The system may further comprise a movable plate comprising one or more cut-outs. The movable plate may be (i) optically aligned with one or more of the plurality of illumination sources and (ii) configured to move so as to (a) control an exposure of the one or more illumination sources through the one or more cut-outs, relative to a pre-determined frame capture rate, and (b) generate one or more light pulses based on the controlled exposure of the one or more illumination sources.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Abstract: The present disclosure provides systems and methods for processing laser speckle signals. The method may comprise obtaining a laser speckle signal from a laser speckle pattern generated using at least one laser light source that is directed towards a tissue region of a subject and a reference signal corresponding to a movement of a biological material of or within the subject's body. The method may comprise computing one or more measurements using a first function corresponding to at least the laser speckle signal and a second function corresponding to the reference signal. The method may comprise generating an output signal in part based on the one or more measurements for the function space and using the output signal to aid a surgical procedure on or near the tissue region of the subject.

Abstract: The present disclosure provides systems and methods for processing laser speckle signals. The method may comprise obtaining a laser speckle signal from a laser speckle pattern generated using at least one laser light source that is directed towards a tissue region of a subject and a reference signal corresponding to a movement of a biological material of or within the subject's body. The method may comprise computing one or more measurements using a first function corresponding to at least the laser speckle signal and a second function corresponding to the reference signal. The method may comprise generating an output signal in part based on the one or more measurements for the function space and using the output signal to aid a surgical procedure on or near the tissue region of the subject.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.

Abstract: The present disclosure provides systems and methods for processing laser speckle signals. The method may comprise obtaining a laser speckle signal from a laser speckle pattern generated using at least one laser light source that is directed towards a tissue region of a subject and a reference signal corresponding to a movement of a biological material of or within the subject's body. The method may comprise computing one or more measurements using a first function corresponding to at least the laser speckle signal and a second function corresponding to the reference signal. The method may comprise generating an output signal in part based on the one or more measurements for the function space and using the output signal to aid a surgical procedure on or near the tissue region of the subject.

Abstract: The present disclosure provides systems and methods for medical imaging. The system may comprise an optical adapter. The optical adapter may comprise a housing that comprises (1) a first end configured to releasably couple to a scope and (2) a second end configured to releasably couple to a camera. The optical adapter may comprise an image sensor coupled to the housing. The optical adapter may comprise an optics assembly disposed in the housing. The optics assembly may be configured to (1) receive light signals that are reflected from a target site within a subject's body and transmitted through the scope, and (2) reflect a first portion of the light signals onto the image sensor while permitting a second portion of the light signals to pass through to the camera.