Patents by Inventor John Ong
John Ong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9238076Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: GrantFiled: January 16, 2013Date of Patent: January 19, 2016Assignees: Alkermes Pharma Ireland Limited, Amylin Pharmaceuticals, LLCInventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David M. Lokensgard, Henry R. Costantino
-
Publication number: 20150157725Abstract: Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid, at least one additional absorption enhancing agent, and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions.Type: ApplicationFiled: December 15, 2014Publication date: June 11, 2015Inventors: John ONG, Robert JENNINGS, Christopher RHODES, Gregg STETSKO
-
Patent number: 8293871Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: GrantFiled: April 15, 2005Date of Patent: October 23, 2012Assignees: Alkernnes Pharma Ireland Limited, Amylin Pharmaceuticals, Inc.Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino, Christine Smith, David M. Lokensgard, Mark Fineman, John Ong
-
Patent number: 8008255Abstract: Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions.Type: GrantFiled: May 28, 2004Date of Patent: August 30, 2011Assignee: Amylin Pharmaceuticals, Inc.Inventors: John Ong, Robert Jennings, Gregg Stetsko
-
Publication number: 20090291886Abstract: Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions.Type: ApplicationFiled: May 5, 2008Publication date: November 26, 2009Applicant: Amylin Pharmaceuticals, Inc.Inventors: John Ong, Robert Jennings, Christopher Rhodes, Gregg Stetsko
-
Publication number: 20090247463Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: ApplicationFiled: June 12, 2009Publication date: October 1, 2009Applicants: Alkermes, Inc., Amylin Pharmaceuticals, Inc.Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David Lokensgard, Henry R. Costantino
-
Patent number: 7563871Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: GrantFiled: September 14, 2006Date of Patent: July 21, 2009Assignees: Alkermes, Inc., Amylin Pharmaceuticals, Inc.Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David Lokensgard, Henry R. Costantino
-
Publication number: 20090069226Abstract: Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid, at least one additional absorption enhancing agent, and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions.Type: ApplicationFiled: January 12, 2005Publication date: March 12, 2009Applicant: Amylin Pharmaceuticals, Inc.Inventors: John Ong, Robert Jennings, Christopher Rhodes, Gregg Stetsko
-
Publication number: 20090035253Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: ApplicationFiled: April 15, 2005Publication date: February 5, 2009Applicants: AMYLIN PHARMACEUTICALS, INC., ALKEMES CONTROLLED THERAPEUTICS,Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Henry R. Costantino, Christine M. Smith, David Lokensgard, Mark Fineman, John Ong
-
Publication number: 20080119569Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: ApplicationFiled: July 20, 2007Publication date: May 22, 2008Applicant: Alkermes, Inc.Inventors: Steven G. Wright, Troy Christensen, Thean Yeoh, Michael E. Rickey, Joyce M. Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David M. Lokensgard, Henry R. Costantino
-
Publication number: 20070166352Abstract: This invention relates to compositions for the sustained release of biologically active polypeptides, and methods of forming and using said compositions, for the sustained release of biologically active polypeptides. The sustained release compositions of this invention comprise a biocompatible polymer having dispersed therein, a biologically active polypeptide and a sugar.Type: ApplicationFiled: September 14, 2006Publication date: July 19, 2007Applicant: Alkermes, Inc.Inventors: Steven Wright, Troy Christenson, Thean Yeoh, Michael Rickey, Joyce Hotz, Rajesh Kumar, Mark Fineman, Christine Smith, John Ong, David Lokensgard, Henry Costantino
-
Publication number: 20060172001Abstract: Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions.Type: ApplicationFiled: May 28, 2004Publication date: August 3, 2006Applicant: Amylin Pharmaceuticals, Inc.Inventors: John Ong, Robert Jennings, Gregg Stetsko
-
Publication number: 20050215475Abstract: Provided are methods and compositions for enhancing the transmucosal absorption of bioactive peptides and proteins. More particularly, the invention provides compositions for enhancing the transmucosal absorption of bioactive peptides and proteins, such as exendin-4, PYY, PYY3-36, and GLP-1 and their analogs and derivatives, wherein the compositions comprise an absorption enhancing mixture of a cationic polyamino acid, at least one additional absorption enhancing agent, and a buffer that is compatible with the polyamino acid. Also provided are methods for enhancing the transmucosal absorption and bioavailability of bioactive peptides and proteins using such compositions.Type: ApplicationFiled: January 12, 2005Publication date: September 29, 2005Inventors: John Ong, Robert Jennings, Christopher Rhodes, Gregg Stetsko
