Patents by Inventor John Orczyk

John Orczyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for identification and quantification of ENOX2 transcript variants as indications of cancer presence in blood serum and other body fluids based on gold or silver nanoparticle formation
    Patent number: 9891222
    Abstract: The present invention includes a semi-quantitative method for the detection of ENOX2 transcript variants from one or more anti-ENOX2 antibody-binding spots on a blot comprising the steps of: electrophoretically separating proteins from a concentrated blood, serum, or plasma sample from the subject; transferring the electrophoretically separated proteins to a substrate; separating the one or more ENOX2 transcript variants from the one or more anti-ENOX2 antibody-binding spots; and measuring an ENOX2-catalyzed conversion of an ionic silver or gold to a colloidal silver or gold detected by light scattering from the one or more anti-ENOX2 antibody binding spots on the substrate, wherein each of the one or more spots is indicative of the ENOX2 transcript variant. Also provided is the basis for a point of care test to detect ENOX2 transcript variants based on use of colloidal gold or silver complexes with ENOX2 as a rapid simple test for cancer presence.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: February 13, 2018
    Assignee: Mor-Nuco Enterprises, Inc.
    Inventors: D. James Morre, John Orczyk
  • Methods and Compositions for Identification and Quantitation of ENOX2 Transcript Variants as Indications of Cancer Presence in Blood Serum and Other Body Fluids Based on Gold or Silver Nanoparticle Formation
    Publication number: 20170322214
    Abstract: The present invention includes a semi-quantitative method for the detection of ENOX2 transcript variants from one or more anti-ENOX2 antibody-binding spots on a blot comprising the steps of: electrophoretically separating proteins from a concentrated blood, serum, or plasma sample from the subject; transferring the electrophoretically separated proteins to a substrate; separating the one or more ENOX2 transcript variants from the one or more anti-ENOX2 antibody-binding spots; and measuring an ENOX2-catalyzed conversion of an ionic silver or gold to a colloidal silver or gold detected by light scattering from the one or more anti-ENOX2 antibody binding spots on the substrate, wherein each of the one or more spots is indicative of the ENOX2 transcript variant. Also provided is the basis for a point of care test to detect ENOX2 transcript variants based on use of colloidal gold or silver complexes with ENOX2 as a rapid simple test for cancer presence.
    Type: Application
    Filed: May 4, 2017
    Publication date: November 9, 2017
    Inventors: D. James Morre, John Orczyk