Patents by Inventor John P. Adelman

John P. Adelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small and intermediate conductance, calcium-activated potassium channels and uses thereof
    Publication number: 20020192757
    Abstract: This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium-activated potassium channel proteins and the nucleic acids encoding calcium-activated proteins. The invention also provides methods for assaying compounds which increase or decrease potassium ion flux through a calcium-activated potassium channel.
    Type: Application
    Filed: April 3, 2002
    Publication date: December 19, 2002
    Applicant: Oregon Health Sciences University
    Inventors: John P. Adelman, James Maylie, Chris T. Bond, Christopher P. Silvia
  • SMALL AND INTERMEDIATE CONDUCTANCE, CALCIUM-ACTIVATED POTASSIUM CHANNELS AND USES THEREOF
    Publication number: 20020165379
    Abstract: This invention relates to small and intermediate conductance, calciumactivated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calciumactivated potassium channel proteins and the nucleic acids encoding calciumactivated potassium channel proteins. The invention also provides methods and compositions for assaying compounds which increase or decrease potassium ion flux through a calciumactivated potassium channel.
    Type: Application
    Filed: May 24, 1999
    Publication date: November 7, 2002
    Inventors: JOHN P. ADELMAN, JAMES MAYLIE, CHRIS T. BOND, CHRISTOPHER P. SILVIA
  • Small and intermediate conductance, calcium-activated potassium channels and uses thereof
    Publication number: 20020155531
    Abstract: This invention relates to small and intermediate conductance, calcium activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and detecting calcium activated potassium channel proteins and the nucleic acids encoding calcium activated potassium channel proteins. The invention also provides methods and compositions for assaying compounds which increase or decrease potassium ion flux through a calcium activated potassium channel.
    Type: Application
    Filed: August 3, 2001
    Publication date: October 24, 2002
    Inventors: John P. Adelman, James Maylie, Chris T. Bond, Christopher P. Silvia
  • DNA encoding ATP-sensitive potassium channel genes
    Patent number: 5744594
    Abstract: This invention relates to DNA and protein compositions useful in the diagnosis and treatment of diabetes, heart disease and skeletal muscle disease. More specifically, this invention relates to DNA and protein compositions for ATP-sensitive potassium channel proteins, and methods of using these compositions.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: April 28, 1998
    Assignee: Oregon Health Sciences University
    Inventors: John P. Adelman, Michael J. Ashford, Chris T. Bond
  • Prepro-LHRH C-terminal peptide DNA
    Patent number: 5075224
    Abstract: DNA encoding a novel polypeptide hormone, designated CTP, has been identified in the human genome. CTP is expressed as a fusion protein (proLHRH) with luteinizing hormone releasing hormone (LHRH), and is post-translationally processed to CTP and LHRH. CTP, its derivatives, and its fusions, including proLHRH, are useful in therapy and diagnostics.
    Type: Grant
    Filed: April 2, 1991
    Date of Patent: December 24, 1991
    Assignee: Genentech, Inc.
    Inventors: Peter H. Seeburg, John P. Adelman
  • Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
    Patent number: 5006469
    Abstract: cDNA encoding a precursor peptide for motilin has been retrieved from porcine gut tissue. The precursor protein contains a motilin-associated peptide (MAP) sequence conjugated to the motilin peptide through a trypsin-like cleavage site. The MAP is useful in regulating alimentary physiology in vertebrates. The DNA provides a means to obtain the corresponding DNAs in other vertebrate species, including humans. It also makes available recombinant motilin, motilin precursor, and MAP of any desired species.
    Type: Grant
    Filed: February 9, 1988
    Date of Patent: April 9, 1991
    Assignee: Oregon Health Sciences University
    Inventors: John P. Adelman, Chris T. Bond, Gajanan Nilaver, Earl A. Zimmerman