Patents by Inventor John P. Alsobrook

John P. Alsobrook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NON-INVASIVE SKIN COLLECTION SYSTEM
    Publication number: 20210196247
    Abstract: The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.
    Type: Application
    Filed: February 24, 2021
    Publication date: July 1, 2021
    Inventors: Tara J. PALMER, John P. ALSOBROOK, II, John Daniel DOBAK, III
  • NON-INVASIVE SKIN COLLECTION SYSTEM
    Publication number: 20200383665
    Abstract: The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.
    Type: Application
    Filed: August 25, 2020
    Publication date: December 10, 2020
    Inventors: Tara J. PALMER, John P. ALSOBROOK, II, John Daniel DOBAK, III
  • NON-INVASIVE SKIN COLLECTION SYSTEM
    Publication number: 20200289099
    Abstract: The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.
    Type: Application
    Filed: May 28, 2020
    Publication date: September 17, 2020
    Inventors: Tara J. PALMER, John P. ALSOBROOK, II, John Daniel DOBAK, III
  • Non-invasive skin collection system
    Patent number: 10709428
    Abstract: The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: July 14, 2020
    Assignee: DERMTECH, INC.
    Inventors: Tara J. Palmer, John P. Alsobrook, II, John Dobak
  • NON-INVASIVE SKIN COLLECTION SYSTEM
    Publication number: 20180110500
    Abstract: The subject matter described herein provides non-invasive tape stripping methods for the collection of a skin sample. The tape stripping method includes applying and removing at least one adhesive tape, provided that a skin sample is adhered to the adhesive tape after removal. The at least one adhesive tape is supplied in an adhesive skin sample collection kit. The adhesive skin sample collection kit further comprises a sample collector and instructions for use sheet.
    Type: Application
    Filed: April 29, 2016
    Publication date: April 26, 2018
    Inventors: Tara J. PALMER, John P. ALSOBROOK, John DOBAK
  • CHARACTERIZATION OF MELANOMA USING A MOLECULAR SIGNATURE
    Publication number: 20160024595
    Abstract: The present disclosure provides methods for characterizing melanoma in a subject by analyzing genes or gene expression products obtained from the subject. The present disclosure provides methods for distinguishing melanoma in situ from invasive melanoma. The disclosure includes non-invasive methods for obtaining genes or gene expression products from a pigmented skin lesion of a subject.
    Type: Application
    Filed: July 22, 2015
    Publication date: January 28, 2016
    Inventor: John P. ALSOBROOK, II
  • DIAGNOSIS OF MELANOMA BY NUCLEIC ACID ANALYSIS
    Publication number: 20150005184
    Abstract: The present invention provides methods for diagnosing melanoma and/or solar lentigo in a subject by analyzing nucleic acid molecules obtained from the subject. The present invention also provides methods for distinguishing melanoma from solar lentigo and/or dysplastic nevi and/or normal pigmented skin. The methods include analyzing expression or mutations in epidermal samples, of one or more skin markers. The methods can include the use of a microarray to analyze gene or protein profiles from a sample.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 1, 2015
    Applicant: DermTech International
    Inventors: John P. ALSOBROOK, Tara J. PALMER
  • Compositions and Methods of Use for a Fibroblast Growth Factor
    Publication number: 20080009439
    Abstract: The present invention generally relates to compositions and methods of use for a fibroblast growth factor (“FGF”). More particularly, the present invention relates to a nucleotide polymorphism (SNP) of FGF-20, and its fragments, derivatives, variants, homologs, and analogs, as well as their uses in wound healing, and prevention and/or treatment of certain diseases, including but are not limited to, stroke, radiation sickness, mucositis, inflammatory bowel disease, and inflammation (osteoarthritis and rheumatoid arthritis).
    Type: Application
    Filed: November 3, 2004
    Publication date: January 10, 2008
    Inventors: John P. Alsobrook, Joseph Eichen, Denise Lepley, Charles E. Miller, Peter Mezes
  • Polypeptides of FGF-CX
    Patent number: 7253266
    Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: August 7, 2007
    Assignee: CuraGen Corporation
    Inventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, William Grosse
  • Proteins and nucleic acids encoding same
    Patent number: 7109000
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: September 19, 2006
    Assignee: CuraGen Corporation
    Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ferenc L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A. M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia Guo, Charles E. Miller, Esha A. Gangolli
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Patent number: 6974684
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: December 13, 2005
    Assignee: CuraGen Corporation
    Inventors: David W. Anderson, John P. Alsobrook II, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Linda Gorman, Xiaojia Sasha Guo, Nikolai Khramtsov, Denise M. Lepley, John R. MacDougall, Carol E. A. Pena, John A. Peyman, Meera Patturajan, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, Corine A. M. Vernet, Edward Z. Voss, Mei Zhong
  • Proteins and nucleic acids encoding same
    Patent number: 6875570
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: April 5, 2005
    Assignee: CuraGen Corporation
    Inventors: Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, David Stone, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, II, Denise M. Lepley, Catherine E. Burgess, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Martin D. Leach, Richard A. Shimkets
  • Compositions and methods of use for a fibroblast growth factor
    Publication number: 20040214759
    Abstract: In methods of using a fibroblast growth factor, such as for treating, preventing or delaying a proliferation-associated disorder, steps are provided to administer to a subject a therapeutically effective amount of a particular fibroblast growth factor polypeptide, or variant or fragment thereof.
    Type: Application
    Filed: May 9, 2003
    Publication date: October 28, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Joel S. Bader, Ferenc L. Boldog, Catherine E. Burgess, Rajeev A. Chillakuru, Lisa Deegler, Shlomit R. Edinger, Elma R. Fernandes, Linda Gorman, William M. Grosse, John L. Herrmann, Michael E. Jeffers, William J. LaRochelle, Denise M. Lepley, Henri S. Lichenstein, Kumar Namdev, Muralidhara Padigaru, Carol E. A. Pena, Sudhirdas K. Prayaga, Daniel K. Rieger, Richard A. Shimkets, Pascal Valax, Meijia Yang, Zachary Yim, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040096877
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 21, 2003
    Publication date: May 20, 2004
    Inventors: Raymond J. Taupier, Muralidhara Padigaru, Luca Rastelli, Steven Kurt Spaderna, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly Ann Spytek, Suresh G. Shenoy, Li Li, Vladimir Y. Gusev, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Valerie L. Gerlach, Karen Ellerman, John R. MacDougall, David J. Stone, Glennda Smithson
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040086875
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 4, 2002
    Publication date: May 6, 2004
    Inventors: Michele L. Agee, John P. Alsobrook, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, John S. Chant, Amitabha Chaudhuri, Vincent A. DiPippo, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Esha A. Gangolli, Linda Gorman, Valerie Gerlach, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Li Li, Uriel M. Malyankar, John R. MacDougall, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Chean Eng. Ooi, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Steven K. Spaderna, Kimberly A. Spytek, Raymond J. Taupier, Corine A.M. Vernet, Bryan D. Zerhusen, Mei Zhong
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040072997
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 3, 2003
    Publication date: April 15, 2004
    Inventors: John P. Alsobrook, David W. Anderson, Catherine E. Burgess, Shlomit R. Edinger, Karen Ellerman, Katarzyna Furtak, Esha A. Gangolli, Valerie Gerlach, Jennifer A. Gilbert, Erik Gunther, Linda Gorman, Xiaojia (Sasha) Guo, Weizhen Ji, Li Li, Charles E. Miller, Muralidhara Padigaru, Meera Patturajan, Luca Rastelli, John R. MacDougall, Vishnu Mishra, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Suresh G. Shenoy, Raymond J. Taupier, Corine A.M. Vernet, Mei Zhong, Uriel M. Malyankar, Isabelle Millet, Ramesh Kekuda, William M. Grosse
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040068095
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 13, 2002
    Publication date: April 8, 2004
    Inventors: Richard A. Shimkets, Raymond J. Taupier, Catherine E. Burgess, Bryan D. Zerhusen, Peter S. Mezes, Luca Rastelli, Uriel M. Malyankar, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Kimberly Ann Spytek, Li Li, Shlomit Edinger, Valerie Gerlach, Karen Ellerman, John R. MacDougall, Erik Gunther, Isabelle Millet, David J. Stone, Glennda Smithson, Edward S. Szekeres, Weizhen Ji
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040067882
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 5, 2002
    Publication date: April 8, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Melanie Baron, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Andrei Chapoval, Mohanraj Dhanabal, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Seth Ettenberg, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia (Sasha) Guo, Craig Hackett, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Denise M. Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Ann Mazur, Kelly McQueeney, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Vishnu Mishra, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Gary Starling, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Nancy Twomlow, Corine A.M. Vernet, Bryan D. Zerhusen, Edward Z. Voss, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040058338
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 2, 2002
    Publication date: March 25, 2004
    Inventors: Michele L. Agee, John P. Alsobrook, David W. Anderson, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, Elina Catterton, Vincent A. DiPippo, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Bonnie Gould Rothberg, Xiaojia Sasha Guo, John L. Herrmann, Yuan-Di Halvorsen, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, William J. LaRochelle, Denise M. Lepley, Li Li, John R. MacDougall, Charles E. Miller, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Glennda Smithson, Steven K. Spaderna, Kimberly A. Spytek, David J. Stone, Raymond J. Taupier, Corine A.M. Vernet, Edward Z. Voss, Mei Zhong
  • Proteins and nucleic acids encoding same
    Publication number: 20040052806
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 4, 2002
    Publication date: March 18, 2004
    Inventors: Ramesh Kekuda, John P. Alsobrook, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Meera Patturajan, William M. Grosse, Denise M. Lepley, Catherine E. Burgess, Corine A.M. Vernet, Li Li, Linda Gorman, Shlomit R. Edinger, Paul Sciore, Karen Ellerman, Uriel M. Malyankar, Mark E. Rothenberg, David J. Stone, Ferenc L. Boldog, Xiaojia (Sasha) Guo, Suresh G. Shenoy, David W. Anderson, Muralidhara Padigaru, Raymond J. Taupier, Charles E. Miller, Andrew Eisen