Patents by Inventor John P. Carr
John P. Carr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220023424Abstract: The present invention is related to methods for lowering peroxide levels in sucrose acetate isobutyrate formulations and to composition used in and formed by such methods.Type: ApplicationFiled: June 30, 2021Publication date: January 27, 2022Inventors: Gunjan Junnarkar, Michael A. Desjardin, John P. Carr
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Patent number: 11083796Abstract: The present invention is related to methods for lowering peroxide levels in sucrose acetate isobutyrate formulations and to composition used in and formed by such methods.Type: GrantFiled: August 15, 2019Date of Patent: August 10, 2021Assignee: Durect CorporationInventors: Gunjan Junnarkar, Michael A. Desjardin, John P. Carr
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Publication number: 20190365900Abstract: The present invention is related to methods for lowering peroxide levels in sucrose acetate isobutyrate formulations and to composition used in and formed by such methods.Type: ApplicationFiled: August 15, 2019Publication date: December 5, 2019Inventors: Gunjan Junnarkar, Michael A. Desjardin, John P. Carr
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Publication number: 20160361420Abstract: The present invention is related to methods for lowering peroxide levels in sucrose acetate isobutyrate formulations and to composition used in and formed by such methods.Type: ApplicationFiled: August 29, 2016Publication date: December 15, 2016Applicant: DURECT CORPORATIONInventors: Gunjan Junnarkar, Michael A. Desjardin, John P. Carr
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Publication number: 20090180349Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to manually mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The manually actuated apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: ApplicationFiled: October 27, 2008Publication date: July 16, 2009Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing, Kenneth R. Gleason, Damian Bianchi
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Patent number: 7441943Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to manually mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The manually actuated apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: GrantFiled: February 14, 2006Date of Patent: October 28, 2008Assignee: Advanced Biomaterial Systems, Inc.Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing, Kenneth R Gleason, Damian Bianchi
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Patent number: 7311436Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: GrantFiled: October 4, 2005Date of Patent: December 25, 2007Assignee: Advanced Biomaterial Systems, Inc.Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing, Damian Bianchi
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Patent number: 7029163Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to manually mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The manually actuated apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: GrantFiled: August 8, 2003Date of Patent: April 18, 2006Assignee: Advanced Biomaterial Systems, Inc.Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing, Kenneth R Gleason, Damian Bianchi
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Patent number: 6984063Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: GrantFiled: May 15, 2003Date of Patent: January 10, 2006Assignee: Advanced Biomaterial Systems, Inc.Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing, Damian Bianchi
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Publication number: 20040196735Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to manually mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The manually actuated apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: ApplicationFiled: August 8, 2003Publication date: October 7, 2004Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing, Kenneth R. Gleason, Damian Bianchi
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Publication number: 20040066706Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The apparatus of the invention comprises: (1) a sealed mixing chamber for mixing components; (2) a dispensing chamber isolated from the sealed mixing chamber; (3) a controllable portal to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism associated with the dispensing chamber to force the mixed contents from the dispensing chamber.Type: ApplicationFiled: May 15, 2003Publication date: April 8, 2004Inventors: Donald Barker, Roy B. Bogert, John P. Carr, James W. Nelson, Linda M. Trebing
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Patent number: 6682522Abstract: An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.Type: GrantFiled: December 4, 2002Date of Patent: January 27, 2004Assignee: Alza CorporationInventors: John P. Carr, James B. Eckenhoff
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Publication number: 20030093063Abstract: An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.Type: ApplicationFiled: December 4, 2002Publication date: May 15, 2003Inventors: John P. Carr, James B. Eckenhoff, Bonnie Burdett Dennis
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Patent number: 6508808Abstract: An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.Type: GrantFiled: December 21, 2000Date of Patent: January 21, 2003Assignee: Alza CorporationInventors: John P. Carr, James B. Eckenhoff
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Patent number: 5972370Abstract: The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation containing a liquid suspension comprising at least 5% by weight beneficial agent and having a viscosity and beneficial agent size which minimizes settling of the agent in suspension over the extended delivery period.Type: GrantFiled: January 28, 1999Date of Patent: October 26, 1999Assignee: Alza CorporationInventors: James B. Eckenhoff, deceased, Leslie A. Holladay, John Joseph Leonard, Jr., Iris K. M. Leung, Sally A. Tao, Judy A. Magruder, John P. Carr, Jeremy C. Wright
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Patent number: 5904935Abstract: The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation containing a liquid suspension comprising at least 5% by weight beneficial agent and having a viscosity and beneficial agent size which minimizes settling of the agent in suspension over the extended delivery period.Type: GrantFiled: June 7, 1995Date of Patent: May 18, 1999Assignee: ALZA CorporationInventors: James B. Eckenhoff, deceased, Leslie A. Holladay, John Joseph Leonard, Jr., Iris K. M. Leung, Sally A. Tao, Judy A. Magruder, John P. Carr, Jeremy Wright
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Patent number: 5462741Abstract: A fluid-activated delivery device is disclosed comprising a housing defining an internal compartment, a beneficial agent formulation in the compartment, exit means in the housing for delivering the beneficial agent formulation from the delivery device, and wherein the formulation comprises an active agent in an amount of 50 wt % or greater blended with a glyceride or a mixture of glycerides of a fatty acid.Type: GrantFiled: April 28, 1994Date of Patent: October 31, 1995Assignee: Alza CorporationInventors: John P. Carr, Steven D. Larsen, James B. Eckenhoff
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Patent number: 5431919Abstract: The present invention is concerned with improving the delivery of a drug from a ruminal delivery device to give a consistent delivery of drug to the ruminal environment. Thus, the invention is directed to an improved ruminal drug delivery device comprising a semipermeable membrane having an exit orifice and defining a compartment, the compartment containing a swellable osmotic agent expandable member, a drug to be dispensed, a density element and, optionally, a partition layer between the osmotic expandable member and the drug formulation, wherein the improvement comprises an essentially gas-impermeable barrier means that separates the density element from the other components within the delivery device for isolating gases evolved from the density element from the other components within the delivery device. The invention is also directed to methods and articles for providing a consistent delivery of drug from a ruminal drug delivery device.Type: GrantFiled: June 23, 1993Date of Patent: July 11, 1995Assignee: ALZAInventors: Fred Maruyama, John P. Carr, James B. Eckenhoff
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Patent number: 5368863Abstract: The present invention is directed to an improvement in a delivery device, the device comprising a wall that surrounds an internal lumen or compartment which contains a beneficial agent or medicament formulation, an expandable driving member and an optional density member, and having an exit means, and wherein the improvement comprises prehydrating the delivery device as a means for advancing the beginning or startup of agent delivery from the delivery system to give earlier release of beneficial agent to the environment of use. An embodiment of the invention concerns a fluid reservoir in contact with the expandable driving member to provide prehydration of the device.Type: GrantFiled: January 21, 1993Date of Patent: November 29, 1994Assignee: Alza CorporationInventors: James B. Eckenhoff, Terry L. Burkoth, John P. Carr, Jeremy C. Wright
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Patent number: 5227167Abstract: The invention provides a dispensing device comprising a loading dose (first agent delivery means) for short-term and continuous delivery of an agent having a high potency, retained together with a long-term dispensing device (second agent delivery means) capable of a long-term and continuous delivery of agent. The combination of first and second agent delivery means provides a device in which a substantially constant dose of beneficial agent may be delivered to the environment of use over time. A rapid initial delivery of beneficial agent is followed by continuous and prolonged delivery of agent.Type: GrantFiled: February 27, 1992Date of Patent: July 13, 1993Assignee: ALZA CorporationInventors: John P. Carr, James B. Eckenhoff, Terry L. Burkoth