Patents by Inventor John P. Coghlan

John P. Coghlan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybridization histochemistry method for determining the presence and location in animal or plant tissue of RNA
    Patent number: 6265156
    Abstract: A method for determining the presence and location in animal or plant tissue of a specific polynucleotide population comprising: (a) preparing a section of the tissue to be examined; (b) contacting the tissue section under hybridization conditions with a synthetic, labelled oligonucleotide probe which is complementary to a representative portion of the target polynucleotide; (c) removing unhybridized probe material from the tissue section; and (d) detecting or identifying the locations in the tissue section where labelling or hybridization of the labelled probe has occurred. A diagnostic kit for use in performance of the above method is also disclosed.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: July 24, 2001
    Assignee: Howard Florey Institute of Experimental Physiology and Medicine
    Inventors: John P. Coghlan, Jennifer D. Penschow, Geoffrey W. Tregear, Hugh D. Niall
  • Hybridization histochemistry method for determining the presence and location in animal or plant tissue of RNA
    Patent number: 5597692
    Abstract: A method for determining the presence and location in animal or plant tissue of a specific polynucleotide population comprising: (a) preparing a section of the tissue to be examined; (b) contacting the tissue section under hybridization conditions with a synthetic, labelled oligonucleotide probe which is complementary to a representative portion of the target polynucleotide; (c) removing unhybridized probe material from the tissue section; and (d) detecting or identifying the locations in the tissue section where labelling by hybridization of the labelled probe has occurred. A diagnostic kit for use in performance of the above method is also disclosed.
    Type: Grant
    Filed: December 30, 1988
    Date of Patent: January 28, 1997
    Assignee: Howard Florey Institute of Experimental Physiology and Medicine
    Inventors: John P. Coghlan, Jennifer D. Penschow, Geoffrey W. Tregear, Hugh D. Niall