Patents by Inventor John P. Dusza

John P. Dusza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-Heteroaryl[1,2,4]triazolo[1,5-a]pyrimidines
    Patent number: 4444774
    Abstract: This disclosure describes 7-heteroaryl[1,2,4]triazolo[1,5-a]pyrimidines which are useful as anxiolytic agents.
    Type: Grant
    Filed: July 29, 1982
    Date of Patent: April 24, 1984
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • Therapeutically active 3-amino-1-phenyl(and substituted phenyl)-2-pyrazolines
    Patent number: 4432991
    Abstract: This disclosure describes certain 3-amino-1-phenyl-2-pyrazolines and 3-amino-1-substituted phenyl-2-pyrazolines and their C4 and C5 analogs useful for meliorating the inflammation and/or the progressive joint deterioration characteristic of arthritic disease, preventing the onset of asthmatic symptoms and allergic diseases, or as analgesic, antibacterial or antifungal agents.
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: February 21, 1984
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • 1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines
    Patent number: 4421753
    Abstract: This disclosure describes novel 1-(5-amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines which are useful as hypotensive agents in mammals.
    Type: Grant
    Filed: March 22, 1982
    Date of Patent: December 20, 1983
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, Walter E. Meyer, John P. Dusza
  • Substituted phenyl-5-aminopyrazoles
    Patent number: 4393217
    Abstract: This disclosure describes novel substituted phenyl-5-aminopyrazoles useful as anxiolytic and/or anti-depressant agents.
    Type: Grant
    Filed: January 12, 1981
    Date of Patent: July 12, 1983
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • Novel 3-substituted amino-1-heteroaryl-2-pyrazolines
    Patent number: 4376122
    Abstract: This disclosure describes novel 3-substituted amino-1-heteroaryl-2-pyrazolines and their C5 analogs, effective an antibacterial and antifungal agents.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: March 8, 1983
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • 4-Heteroarylimidazo-[1,5-A]pyrimidines
    Patent number: 4374988
    Abstract: Novel pyrimidine compounds are disclosed of the class represented by the formula: ##STR1## wherein R.sub.1 is selected from the class consisting essentially of hydrogen, chloro, bromo, cyano (--CN), carbamoyl (--CO--NH.sub.2), carboxyl (--COOH), and lower alkoxycarbonyl (--CO--O--R.sub.3, where R.sub.3 is a lower alkyl radical having 1-4 carbon atoms), and wherein R.sub.2 is a monovalent radical selected from the class consisting essentially of furyl, thienyl, 3-pyridyl and 3-pyridyl-N-oxide, either of said pyridyl radicals optionally being substituted with an alkyl radical having from 1 to 4 carbon atoms. Processes of preparing such compounds are disclosed.The novel compounds are useful as anxiolytic agents in ameliorating anxiety in a mammal.
    Type: Grant
    Filed: November 5, 1981
    Date of Patent: February 22, 1983
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • Therapeutically active 3-amino-1-phenyl and substituted phenyl-2-pyrazolines
    Patent number: 4360680
    Abstract: A method of treating pain, meliorating inflammation in warm-blooded animals as well as a method for treating fungal and bacterial infections in such animals using certain 3-amino-1-phenyl-2-pyrazolines and 3-amino-1-substituted phenyl-2-pyrazolines and their C4 and C5 analogs, as well as compounds used in the above are disclosed.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: November 23, 1982
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • 3-Trifluoroacetyl amino-1-aryl-2-pyrazolines
    Patent number: 4348527
    Abstract: This disclosure describes novel 3-substituted amino-1-phenyl-2-pyrazolines and 3-substituted amino-1-mono and disubstituted phenyl-2-pyrazolines and their C.sub.4 and C.sub.5 analogs, effective as anti-inflammatory and analgesic agents, and as antibacterial agents and/or antifungal agents.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: September 7, 1982
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines
    Patent number: 4347251
    Abstract: This disclosure describes novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines and their C.sub.4 and C.sub.5 analogs, effective as agents that ameliorate inflammation, analgesic agents, antibacterial agents and/or anti-fungal agents.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: August 31, 1982
    Assignee: American Cyanamid Company
    Inventors: Joseph P. Joseph, John P. Dusza, Seymour Bernstein
  • Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents
    Patent number: 4281000
    Abstract: This disclosure describes substituted pyrazolo[1,5-a]pyrimidines which possess anxiolytic activity.
    Type: Grant
    Filed: February 26, 1980
    Date of Patent: July 28, 1981
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • 2-Pyridylhydrazides
    Patent number: 4260767
    Abstract: 2-Pyridylhydrazides useful as antiinflammatory agents.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: April 7, 1981
    Assignee: American Cyanamid Company
    Inventor: John P. Dusza
  • 6- And 8-heteroaryl-1,2,4-triazolo[4,3-b]pyridazines
    Patent number: 4260756
    Abstract: This disclosure describes novel 6- and 8-heteroaryl and substituted 6- and 8-heteroaryl-1,2,4-triazolo[4,3-b]-pyridazines and their use as agents for treating anxiety.
    Type: Grant
    Filed: November 15, 1979
    Date of Patent: April 7, 1981
    Assignee: American Cyanamid Company
    Inventors: Daniel B. Moran, John P. Dusza, Jay D. Albright
  • Imidazo[1,5-a]pyrimidines
    Patent number: 4236005
    Abstract: This disclosure describes substituted pyrazolo[1,5-a]pyrimidines and imidazo[1,5-a]pyrimidines which possess anxiolytic activity.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: November 25, 1980
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • (Substituted-phenyl)-1,2,4-triazolo[4,3-a]-pyrimidines and (substituted-phenyl)-1,2,4-triazolo[1,5-a]pyrimidines
    Patent number: 4209621
    Abstract: This disclosure describes substituted 1,2,4-triazolo[1,5-a]pyrimidines and substituted 1,2,4-triazolo[4,3-a]pyrimidines which possess anxiolytic activity.
    Type: Grant
    Filed: April 27, 1979
    Date of Patent: June 24, 1980
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Robert A. Hardy, Jr., Jay D. Albright
  • Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines
    Patent number: 4178449
    Abstract: This disclosure describes substituted pyrazolo[1,5-a]pyrimidines and imidazo[1,5-a]pyrimidines which possess anxiolytic activity.
    Type: Grant
    Filed: December 15, 1978
    Date of Patent: December 11, 1979
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright