Abstract: The disclosed invention is a method for detecting indications of the presence of Alzheimer's disease (AD) and related dementia-inducing, motor-control-related pathologies, and other diseases in the human brain using a magnetic-resonance based technique for measuring fine tissue and bone textures. Specifically, the invention focuses on refinements/adaptations to a prior art magnetic resonance fine texture measurement technique that facilitates/enables pushing the detection limits closer to the cellular level, so as to be able to measure the fine scale structures and tissue changes that are known to be characteristic of the neurodegenerative processes involved in the development of these diseases.

Abstract: The inventive technology describes to a novel surgical device having a high-speed rotating hollow cutting needle capable of longitudinally cutting, sampling, removing and/or coring targeted tissue pathologies as well as the efficient collection and/or disposal of said tissue pathologies. In particular, the inventive technology may be suitable for application on lesions near the skin, and/or pathologies internal to the body, and perhaps even especially for procedures performed in conjunction with image guidance, particularly active X-ray, computerized tomography (CT), magnetic resonance imaging (MRI), and/or ultrasound scans, where the presence of a large electro-magnetic field may impose significant constraints on the design and operation of mechanical mechanisms.