Patents by Inventor John P. Mallamo

John P. Mallamo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEASOME INHIBITORS AND PROCESSES FOR THEIR PREPARATION, PURIFICATION AND USE
    Publication number: 20140121182
    Abstract: The invention provides boronic esters of Formula (I) wherein R is H or methyl, and methods for the preparation and purification thereof.
    Type: Application
    Filed: June 21, 2012
    Publication date: May 1, 2014
    Applicant: Cephalon, Inc.
    Inventors: Roger P. Bakale, John P. Mallamo, Renee Caroline Roemmele
  • Substituted thioacetamides
    Patent number: 7268132
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: September 11, 2007
    Assignee: Cephalon, Inc.
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo
  • Hydroxamate-containing cysteine and serine protease inhibitors
    Patent number: 7060683
    Abstract: The present invention is directed to hydroxamate-containing inhibitors of cysteine and serine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: June 13, 2006
    Assignee: Cephalon, Inc.
    Inventors: Kurt Allen Josef, John P. Mallamo, Ron Bihovsky
  • Peptide-containing ?-ketoamide cysteine and serine protease inhibitors
    Patent number: 7001907
    Abstract: This invention relates to peptide-containing ?-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: February 21, 2006
    Assignee: Cephaon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Substituted thioacetamides
    Patent number: 6919367
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: July 19, 2005
    Assignee: Cephalon, Inc.
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Matthew S. Miller, Rabindranath Tripathy, Jeffry L. Vaught
  • Selected derivatives of K-252a
    Patent number: 6875865
    Abstract: Disclosed herein are selected indolocarbazole derivatives which are represented by the general formula: The compounds are useful for enhancing the function and/or survival of a trophic factor responsive cell. They inhibit interleukin-2 production and have immunosuppressive activity.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: April 5, 2005
    Assignee: Cephalon, Inc.
    Inventors: Robert L. Hudkins, John P. Mallamo, Masami Hamano, Rieko Tanaka, Chikara Murakata
  • Substituted thioacetamides
    Publication number: 20040116445
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Application
    Filed: November 18, 2003
    Publication date: June 17, 2004
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Matthew S. Miller, Rabindranath Tripathy, Jeffry L. Vaught
  • Hydroxamate-containing cysteine and serine protease inhibitors
    Publication number: 20040106558
    Abstract: The present invention is directed to hydroxamate-containing inhibitors of cysteine and serine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Application
    Filed: November 20, 2003
    Publication date: June 3, 2004
    Applicant: Cephalon, Inc.
    Inventors: Kurt Allen Josef, John P. Mallamo, Ron Bihovsky
  • Peptide-containing alpha-ketoamide cysteine and serine protease inhibitors
    Publication number: 20040102609
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Application
    Filed: October 14, 2003
    Publication date: May 27, 2004
    Applicant: Cephalon Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Peptide-containing &agr;-ketoamide cysteine and serine protease inhibitors
    Patent number: 6703368
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Grant
    Filed: June 12, 2001
    Date of Patent: March 9, 2004
    Assignee: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Hydroxamate-containing cysteine and serine protease inhibitors
    Patent number: 6686335
    Abstract: The present invention is directed to hydroxamate-containing inhibitors of cysteine and serine proteases. Methods for the use of the protease inhibitors are also described.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: February 3, 2004
    Assignee: Cephalon, Inc.
    Inventors: Kurt Allen Josef, John P. Mallamo, Ron Bihovsky
  • Substituted thioacetamides
    Patent number: 6670358
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: December 30, 2003
    Assignee: Cephalon, Inc.
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Matthew S. Miller, Rabindranath Tripathy, Jeffry L. Vaught
  • Substituted thioacetamides
    Patent number: 6492396
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: December 10, 2002
    Assignee: Cephalon, Inc.
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Jeffry L. Vaught, Matthew S. Miller
  • Substituted thioacetamides
    Publication number: 20020183334
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Application
    Filed: October 26, 2001
    Publication date: December 5, 2002
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Matthew S. Miller, Rabindranath Tripathy, Jeffry L. Vaught
  • Peptide-containing alpha-ketoamide cysteine and serine protease inhibitors
    Publication number: 20020055616
    Abstract: This invention relates to peptide-containing &agr;-ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.
    Type: Application
    Filed: June 12, 2001
    Publication date: May 9, 2002
    Applicant: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo, Ron Bihovsky, Gregory J. Wells
  • Substituted thioacetamides
    Publication number: 20020045629
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Application
    Filed: May 15, 2001
    Publication date: April 18, 2002
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Jeffry L. Vaught
  • Bridged indenopyrrolocarbazoles
    Patent number: 6359130
    Abstract: The present invention is directed to novel fused aryl and heteroaryl bridged indenopyrrolocarbazoles which are useful, inter alia, as therapeutic agents. The invention is also directed to methods for making and using the bridged indenopyrrolocarbazoles.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: March 19, 2002
    Assignee: Cephalon, Inc.
    Inventors: Jasbir Singh, Robert L. Hudkins, John P. Mallamo, Theodore L. Underiner, Rabindranath Tripathy
  • &agr;-ketoamide multicatalytic protease inhibitors
    Patent number: 6310057
    Abstract: This invention relates to &agr;-ketoamide inhibitors of multicatalytic protease (MCP), to compositions including such inhibitors, and to methods for the use of MCP inhibitors. The MCP inhibitors of the present invention are useful, for example, to retard loss of muscle mass incident to various physiological states.
    Type: Grant
    Filed: March 7, 2000
    Date of Patent: October 30, 2001
    Assignee: Cephalon, Inc.
    Inventors: Sankar Chatterjee, John P. Mallamo
  • Substituted thioacetamides
    Patent number: RE39575
    Abstract: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
    Type: Grant
    Filed: November 23, 2004
    Date of Patent: April 17, 2007
    Assignee: Cephalon, Inc.
    Inventors: Edward R. Bacon, Sankar Chatterjee, Derek Dunn, John P. Mallamo, Jeffry L. Vaught, Matthew S. Miller
  • Selected soluble esters of hydroxyl-containing indolocarbazoles
    Patent number: RE38332
    Abstract: Esters of hydroxyl-containing indolocarbazoles and acids containing selected solubilizing groups are provided. Compositions including the indolocarbazole esters and methods for the use of the indolocarbazole esters are also provided.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: November 25, 2003
    Assignees: Cephalon, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: John P. Mallamo, Robert L. Hudkins