Patents by Inventor John P. Morris, IV

John P. Morris, IV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY WITH MEK INHIBITOR AND CDK4/6 INHIBITOR TO TREAT PANCREATIC CANCER
    Publication number: 20240108628
    Abstract: The present technology provides methods for treating pancreatic cancer using a MEK inhibitor and a CDK4/6 inhibitor. Also disclosed herein are methods for increasing patient responsiveness to chemotherapeutic and/or immunotherapeutic regimes for pancreatic cancer. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: April 24, 2023
    Publication date: April 4, 2024
    Inventors: Marcus Ruscetti, John P. Morris, IV, Scott Lowe
  • Combination therapy with MEK inhibitor and CDK4/6 inhibitor to treat pancreatic cancer
    Patent number: 11633401
    Abstract: The present technology provides methods for treating pancreatic cancer using a MEK inhibitor and a CDK4/6 inhibitor. Also disclosed herein are methods for increasing patient responsiveness to chemotherapeutic and/or immunotherapeutic regimes for pancreatic cancer. Kits for use in practicing the methods are also provided.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: April 25, 2023
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Marcus Ruscetti, John P. Morris, IV, Scott Lowe
  • METHODS OF TREATING P53 MUTANT CANCERS USING OGDH INHIBITORS
    Publication number: 20220280538
    Abstract: The present technology relates generally to methods and compositions for treating, preventing, and/or ameliorating p53-mutant cancers in a subject in need thereof, including acute myeloid leukemia (AML), pancreatic cancer, and liver cancer, by administration of a therapeutically effective amount of a 2-oxoglutarate dehydrogenase (OGDH) inhibitor.
    Type: Application
    Filed: August 13, 2020
    Publication date: September 8, 2022
    Inventors: Scott LOWE, John P. MORRIS, IV, Scott E. MILLMAN, Lydia FINLEY
  • COMBINATION THERAPY WITH MEK INHIBITOR AND CDK4/6 INHIBITOR TO TREAT PANCREATIC CANCER
    Publication number: 20210205319
    Abstract: The present technology provides methods for treating pancreatic cancer using a MEK inhibitor and a CDK4/6 inhibitor. Also disclosed herein are methods for increasing patient responsiveness to chemotherapeutic and/or immunotherapeutic regimes for pancreatic cancer. Kits for use in practicing the methods are also provided.
    Type: Application
    Filed: July 3, 2019
    Publication date: July 8, 2021
    Inventors: Marcus Ruscetti, John P. Morris, IV, Scott Lowe