Patents by Inventor John P. Pirro

John P. Pirro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Patent number: 6958141
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: October 25, 2005
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Publication number: 20040191174
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising
    Type: Application
    Filed: December 19, 2003
    Publication date: September 30, 2004
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Patent number: 6699458
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: March 2, 2004
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • RHENIUM AND TECHNETIUM COMPLEXES CONTAINING A HYPOXIA-LOCALIZING MOIETY
    Publication number: 20040010127
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising
    Type: Application
    Filed: November 16, 2001
    Publication date: January 15, 2004
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Publication number: 20020054853
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising
    Type: Application
    Filed: February 5, 2001
    Publication date: May 9, 2002
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Patent number: 6359120
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: March 19, 2002
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Rhenium and technetium complexes containing a hypoxia-localizing moiety
    Patent number: 6184361
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprising a metal, preferably radionuclide of rhenium or technetium; a hypoxia-localizing moiety; and, a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: February 6, 2001
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Rhenium and technetium complexes containing a hypoxia localizing moiety
    Patent number: 5808091
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comnprisinga metal, preferably radionuclide of rhenium or technetium;a hypoxia-localizing moiety; and,a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: September 15, 1998
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro
  • Diagnostic imaging methods using rhenium and technetium complexes containing a hypoxia-localizing moiety
    Patent number: 5688487
    Abstract: Novel methods, processes and metal complexes attached to a hypoxia-localizing moiety comprisinga metal, preferably radionuclide of rhenium or technetium;a hypoxia-localizing moiety; and,a complexing ligand, wherein said ligand and said radionuclide combined have cell membrane permeabilities greater than that of sucrose, are disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 18, 1997
    Assignee: Bracco International B.V.
    Inventors: Karen Linder, Adrian D. Nunn, David P. Nowotnik, Kondareddiar Ramalingam, Richard J. DiRocco, William L. Rumsey, John P. Pirro