Patents by Inventor John P. Seibyl

John P. Seibyl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of determining the activity of a central nervous system drug on striatal dopamine transporter populations
    Publication number: 20030130336
    Abstract: This invention relates to a method of predicting the activity of a CNS drug on striatal dopamine transporter populations. The method uses SPECT brain imaging to predict the activity of antidepressants or anxiolytic agents on striatal dopamine transporter populations. The method uses the increase in dopamine transporter populations as a marker for predicting sexual dysfunction side effects, as well as to determine proper dosing for antidepressants or anxiolytics agents in order to avoid the sexual dysfunction side effects.
    Type: Application
    Filed: December 31, 2002
    Publication date: July 10, 2003
    Applicant: Pfizer Inc.
    Inventors: Peter J. Snyder, Robert B. Innis, John P. Seibyl, Akira Kugaya, Stephen A. Williams
  • Dopamine and noradrenergic reuptake inhibitors in treatment of schizophrenia
    Patent number: 5447948
    Abstract: Mazindol and other dopamine and/or noradrenergic reuptake inhibitors are effective to treat negative symptoms in schizophrenia.
    Type: Grant
    Filed: May 7, 1992
    Date of Patent: September 5, 1995
    Assignee: Yale University
    Inventors: John P. Seibyl, John H. Krystal, Dennis S. Charney