Patents by Inventor John P. Shapiro

John P. Shapiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
    Patent number: 5663070
    Abstract: The invention provides soluble forms of the Fas (Apo-1 ) protein comprising both the intracellular and extracellular domains of the full-length polypeptide. Exemplified is a naturally-occurring splice variant of the Fas gene, Fas.DELTA.TM, which lacks the transmembrane domain of the native antigen. DNA encoding the protein, cells expressing the recombinant DNA, and methods of using the protein and DNA are also provided.
    Type: Grant
    Filed: November 15, 1993
    Date of Patent: September 2, 1997
    Assignee: LXR Biotechnology Inc.
    Inventors: Philip J. Barr, John P. Shapiro, Michael C. Kiefer
  • Soluble splice variant of the Fas (APO-1) antigen, Fas.DELTA.TM
    Patent number: 5652210
    Abstract: The invention provides soluble forms of the Fas (Apo-1) protein comprising both the intracellular and extracellular domains of the full-length polypeptide. Exemplified is a naturally-occurring splice variant of the Fas gene, Fas.DELTA.TM, which lacks the transmembrane domain of the native antigen. DNA encoding the protein, cells expressing the recombinant DNA, and methods of using the protein and DNA are also provided.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: July 29, 1997
    Assignee: LXR Biotechnology, Inc.
    Inventors: Philip J. Barr, John P. Shapiro, Michael C. Kiefer