Patents by Inventor John P. Turnbull

John P. Turnbull has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for removing osmium from nucleosides
    Patent number: 5438132
    Abstract: A process for removing osmium from an aqueous solution of nucleosides comprising adding hydrogen sulfide, an aromatic pi base such as pyridine, and a mineral acid. The osmium is precipitated out of solution.
    Type: Grant
    Filed: May 14, 1993
    Date of Patent: August 1, 1995
    Assignee: Glaxo Group Limited
    Inventors: Brian L. Bray, Maynard E. Lichty, John J. Partridge, John P. Turnbull
  • Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone from a 2,3-unsaturated-1-cyclopentanylpurinone
    Patent number: 5233041
    Abstract: Synthesis of the triol of formula (I) or its amine-protected derivative from a cyclopentene of the formula (II) or its amine-protected derivative: ##STR1## via steps including oxidation to the aldehyde, migration of the double bond, reduction of the aldehyde moiety back to the alcohol grouping and 1,2-cis-dihydroxylation of the double bond.
    Type: Grant
    Filed: October 7, 1991
    Date of Patent: August 3, 1993
    Assignee: Glaxo Group Limited
    Inventors: Brian L. Bray, Maynard E. Lichty, John J. Partridge, John P. Turnbull
  • Process for the preparation of a carbocyclic nucleoside analogue
    Patent number: 5110926
    Abstract: A process is described for the preparation of carbocyclic guanosine from aristeromycin in a multi-step procedure, the final step of which is the hydrolysis of a compound of the formula ##STR1## wherein R.sup.1 represents a C.sub.1-6 alkyl group or an arylC.sub.1-4 alkyl group and R.sup.2, R.sup.3 and R.sup.4 each independently represent a hydrogen atom or a hydroxyl protecting group.Carbocyclic guanosine is an intermediate in the synthesis of carbocyclic analogues of nucleosides having use in therapy, particularly as antiviral agents.
    Type: Grant
    Filed: July 18, 1990
    Date of Patent: May 5, 1992
    Assignee: Glaxo Group Limited
    Inventors: Richard Storer, Chi L. Mo, John P. Turnbull