Abstract: A vehicle dash cam may be configured to execute one or more neural networks (and/or other artificial intelligence), such as based on input from one or more of the cameras and/or other sensors associated with the dash cam, to intelligently detect safety events in real-time. Detection of a safety event may trigger an in-cab alert to make the driver aware of the safety risk. The dash cam may include logic for determining which asset data to transmit to a backend server in response to detection of a safety event, as well as which asset data to transmit to the backend server in response to analysis of sensor data that did not trigger a safety event. The asset data transmitted to the backend server may be further analyzed to determine if further alerts should be provided to the driver and/or to a safety manager.

Abstract: An electronic control module (ECM) on-board a machine executes a reduced-order model configured to generate virtual sensor data associated with a machine component based on sensor data measured by actual sensors. The ECM can also execute a machine learning model configured to generate offset data for the sensor data and/or the virtual sensor data, based on operating conditions, an age of the machine component, and/or other factors that the reduced-order model may not consider. The sensor data and/or the virtual sensor data, adjusted based on the offset data, can indicate whether the machine component has failed or is predicted to fail at a future point in time, and/or a remaining usable life of the machine component.

Abstract: A de-hydrogenation catalyst and its use in dehydrogenation of hydrocarbons. The catalyst has low cracking activity and comprises gallium or gallium and platinum on an essentially non-acidic and amorphous alumina-phosphate or silica-alumina-phosphate support with an empirical chemical composition of [Al2O3][SiO2]Y[P2O5]Z, wherein Y is between 0 and 0.2 and Z is between 0.01 and 1.1, with a BET surface area above 50 m2/g, as measured by N2 adsorption experiment.

Abstract: The present disclosure relates to the field of pet foods, and provides a composite nutritional freeze-dried snack containing a bacteriophage and a preparation method and a use thereof. The composite nutritional freeze-dried snack includes a nutritional mixture and an egg. A nutrition proportion provided by each plant extract in the composite nutritional freeze-dried snack provided by the present disclosure can achieve the effects of promoting growth of dogs and cats, resisting oxidation, strengthening immunity, resisting respiratory system infection, preventing pets from infection with pathogens and the like. Therefore, the composite nutritional freeze-dried snack has a good market prospect.

Abstract: The disclosure features compositions and methods for the treatment of sensorineural hearing loss and auditory neuropathy, particularly forms of the disease that are associated with a mutation in otoferlin (OTOF), by way of OTOF gene therapy. The disclosure provides a variety of compositions that include a first nucleic acid vector that contains a polynucleotide encoding an N-terminal portion of an OTOF protein (e.g., an OTOF isoform 5 protein) and a second nucleic acid vector that contains a polynucleotide encoding a C-terminal portion of an OTOF protein (e.g., an OTOF isoform 5 protein). These vectors can be used to increase the expression of OTOF in a subject, such as a human subject suffering from sensorineural hearing loss.

Abstract: Systems and methods for managing permissions and authorizing access to a service supported by a computing device. The methods comprise by a computing device: intercepting a request to access the service sent along with a certificate including a first tenant identifier (the first tenant identifier identifying a first business entity other than a second business entity providing the service); using the first tenant identifier to obtain permission information from a datastore (the permission information specifying which resources of a plurality of resources can be returned in response to requests from the first business entity); generating a web authentication token including the first tenant identifier and the permission information; and initiating operations of the service in response to a validation of the web authentication token.

Abstract: A device orientation calibration system to perform operations that include: accessing inertial measurement unit (IMU) data generated by an IMU mounted upon an object that corresponds with a first reference frame, the IMU data indicating a second reference frame that comprises a Z-axis, a Y-axis, and an X-axis; performing a calibration of the IMU data to align the second reference frame of the IMU with the first reference frame of the object, the performing the calibration comprising: determining a gravitational vector based on a first portion of the IMU data; applying a first rotation to the IMU data to align the Z-axis of the second reference frame with the gravitational vector; determining a forward motion vector based on a second portion of the IMU data; and applying a second rotation to the IMU data to align the X-axis of the second reference frame with the forward motion vector.

Abstract: The present disclosure provides transaminase enzymes having improved properties and are capable of reducing (1S,5R)-6,8-dioxabicyclo[3.2.1]octan-4-one with high selectivity. Also provided are polynucleotides encoding the transaminase enzymes, host cells capable of expressing the transaminase enzymes, and methods of using the transaminase enzymes to synthesize (1S,4R,5R)-6,8-dioxabicyclo[3.2.1]octan-4-amine.

Abstract: The present invention relates to gene fusions and alternative spliced junctions associated with breast cancer. The present invention also relates to novel methods of identifying gene fusions and alternative spliced junctions in RNA sequencing data. The present invention further relates to predicting prognosis of a breast cancer patient based on the number of gene fusion events.

Abstract: A system and method for image data management. A tiled representation of a data set is accessed. The tiled representation includes a plurality of high-resolution tiles and a plurality of reduced-resolution tiles. A request to access said data set from a computing device is received. An image display window is determined based on said request from the computing device, where the image display window corresponds to a displayable image for display on the display device. At least one overlapping image to send the computing device is determined based on said image display window, where the at least one overlapping image is selected from the scaled full images, the plurality of high-resolution tiles, and the plurality of reduced resolution tiles. At least a portion of the at least one overlapping image is sent to the computing device.

Abstract: A system and method for image data management. A tiled representation of a data set is accessed. The tiled representation includes a plurality of high-resolution tiles and a plurality of reduced-resolution tiles. A request to access said data set from a computing device is received. An image display window is determined based on said request from the computing device, where the image display window corresponds to a displayable image for display on the display device. At least one overlapping image to send the computing device is determined based on said image display window, where the at least one overlapping image is selected from the scaled full images, the plurality of high-resolution tiles, and the plurality of reduced resolution tiles. At least a portion of the at least one overlapping image is sent to the computing device.

Abstract: A system and method for image data management. A tiled representation of a data set is accessed. The tiled representation includes a plurality of high-resolution tiles and a plurality of reduced-resolution tiles. A request to access said data set from a computing device is received. An image display window is determined based on said request from the computing device, where the image display window corresponds to a displayable image for display on the display device. At least one overlapping image to send the computing device is determined based on said image display window, where the at least one overlapping image is selected from the scaled full images, the plurality of high-resolution tiles, and the plurality of reduced resolution tiles. At least a portion of the at least one overlapping image is sent to the computing device.

Abstract: A system and method for image data management. A tiled representation of a data set is accessed. The tiled representation includes a plurality of high-resolution tiles and a plurality of reduced-resolution tiles. A request to access said data set from a computing device is received. An image display window is determined based on said request from the computing device, where the image display window corresponds to a displayable image for display on the display device. At least one overlapping image to send the computing device is determined based on said image display window, where the at least one overlapping image is selected from the scaled full images, the plurality of high-resolution tiles, and the plurality of reduced resolution tiles. At least a portion of the at least one overlapping image is sent to the computing device.

Abstract: A backlight unit has a light guide plate with a diffusive layer therein. The light guide plate has a first side, a second side opposite to the first side and a third side. The diffusive layer has a base and a plurality of grains in the base. A lamp is arranged beside the third side of the light plate to provide light to the light guide plate. A reflective film is attached on the second side of the light guide plate to reflect light. A brightness enhance member is provided at the first side of the light guide plate.

Abstract: A substrate has a substrate member, which is made of a polar material, such as Polymethyl methacrylate (PMMA), Methyl methacrylate/Styrene copolymer (MS) or Polycarbonate (PC), having a first side and a second side. On the fist side and the second side of the substrate member provided with an insulating layers respectively, wherein the insulating layers are made of a non-polar material with a low water absorption, such as Cyclic Olefin Polymer (COP) or Cyclic Olefin Copolymer (COC). The water absorption of COP or COC is less than the water absorption of PMMA, MS or PC to prevent the substrate member from warping while the substrate is heated at a single side. Two adhesive layers, which is made of a material with a chemical structure with a non-polar segment and a polar segment, such as olefin/acrylate copolymer, to bond the insulating layers on the substrate member.

Abstract: An apparatus for making wedged plate has an extruder to provide melted plastic material. A die head has a channel with an inlet and an outlet. The inlet of the die head is connected to an outlet of the extruder. The outlet of the die head has a thick side and a narrow side. A rolling device has two rollers and a space between the rollers. The space has a thick portion and a narrow portion at opposite sides. The space of the rolling device is aligned with the outlet of the die head, so that the plastic material flows into the space of the rolling device via the die head and is rolled by the rollers. A cutting device is arranged behind the rolling device to cut the rolled plastic material to get wedged plates.

Abstract: An automatic score dartboard assembly has a base, a dartboard, a support, at least one imaging element and a main control circuit. The dartboard and the support are attached to the base, and the at least one imaging element is mounted on the support to capture a direct viewing image of the dartboard periodically. The images are output to the main control circuit to determine the score of a dart when the dart sticks in the dartboard. The main control circuit is composed of an image processor and a memory device. The image processor uses an image comparison method to determine the score of the dart. Therefore, the present invention uses as few as one imaging element to determine the score and increases accuracy of determining score.

Abstract: A backlight module has a frame, on which a reflective film, lamps and a diffusive plate are provided in sequence. A plurality of positioning devices each have a base and two rings. The base has two channels, two slots and a post on a top thereof. The lamps are fitted to the rings respectively and the rings are mounted in the slots of the base respectively to rest the lamps in the channels. The base of the positioning devices are secured on the bottom plate of the frame and the posts thereof are against the diffusive plate, such that the lamp is suspended and the relative locations of the lamps, the diffusive plate and the reflective film are fixed.

Abstract: A substrate has a substrate member, which is made of Cyclic Olefins Polymer (COP) or Cyclic Olefins Copolymer (COC), and two protective layers, which are made of Polymethyl methacrylate (PMMA) or Polycarbonate (PC), provided on opposite side of the substrate member. The COP or COC substrate member has a less water absorption (<0.01%) to prevent the substrate from warping while it is irradiated at single side. The PMMA or PC protective layer has a greater hardness to protect the substrate from damage.

Abstract: A direct-light illuminating unit has a frame on which a plurality of U-shaped lamps and a plurality of light shade devices are mounted. The frame has a window region and a margin region. The lamps each have two straight portions and a connection portion. The lamps have the straight portions and the connection portions arranged in the window region of the frame. The light shade device has a top mask extended over the connection portions of the lamps respectively. The top masks have a predetermined transparency to shade a part of the light provided from the connection portions of the lamps respectively.