Abstract: A surgical microscope is configured to capture images of an eye of a patient and defines an optical axis. An illumination source is configured to emit a plurality of beams onto the eye of the patient at a plurality of angles relative to the optical axis. A controller is coupled to the surgical microscope and the illumination source, the controller configured to independently control values for illumination parameters for each beam of the plurality of beams to facilitate imaging of the eye of the patient. The illumination parameters may compensate for reflections from the iris, offset of the eye relative to the optical axis, and reflections of ambient light. The illumination parameters may be controlled subject to inputs received from a surgeon or other user.

Abstract: Techniques are provided for single sided beam management in a millimeter wave (mmW) communication system for use in bistatic radio frequency (RF) sensing. An example method of tracking targets with bistatic radio frequency sensing includes receiving a scanning reference signal, generating a scanning signal report indicating one or more target groups associated with the scanning reference signal, transmitting the scanning signal report, receiving tracking signal configuration information indicating a tracking reference signal associated with the one or more target groups, receiving the tracking reference signal identified in the tracking signal configuration information, and tracking the one or more target groups associated with the tracking reference signal.

Abstract: In certain embodiments, a system, a computer-implemented method, and computer-readable medium are disclosed for enhanced ophthalmic visualization. A plurality of images corresponding to different portions of the electromagnetic spectrum are obtained and combined, such as by pixel-wise subtraction to obtain a combined image. The images may be weighted with weights selected to enhance visualization of features, such as layers of the retina or features corresponding to pathologies. The combined image may be processed, such as by a machine learning model, to extract features.

Abstract: In certain embodiments, a system, a computer-implemented method, and computer-readable medium are disclosed for performing integrated analysis of MSI and OCT images to diagnose eye disorders. MSI and OCT are processed using separate input machine learning models to create input feature maps that are input to an intermediate machine learning model. The intermediate machine learning model processes the input feature maps and outputs a final feature map that is processed by one or more output machine learning models that output one or more estimated representations of a pathology of the eye of the patient. A single device captures OCT and non-OCT images using (a) a sensor of a first imaging device that is shared with a second imaging device and/or (b) an optical component for directing light form the retina to the first imaging device or the second imaging device.

Abstract: A system, method, and computer-readable medium for an information technology (IT) ecosystem management and monitoring operation. The IT ecosystem management and monitoring operation includes: executing a sustainability application on a hardware processor of an information handling system; providing an IT ecosystem monitoring and management console, the IT ecosystem monitoring and management console comprising an IT ecosystem sustainability system, the IT ecosystem sustainability system comprising a sustainability component; and, communicating between the sustainability component and the sustainability application to perform an IT environment sustainability operation.

Abstract: A system, method, and computer-readable medium for an information technology (IT) ecosystem management and monitoring operation. The IT ecosystem management and monitoring operation includes: providing a sustainability application to an information handling system, the information handling system comprising a modular component architecture; obtaining sustainability information regarding a component of the information handling system via the sustainability application; providing an IT ecosystem monitoring and management console, the IT ecosystem monitoring and management console comprising an IT ecosystem sustainability system, the IT ecosystem sustainability system comprising a sustainability component; and, communicating between the sustainability component and the sustainability application to perform an IT environment sustainability operation, the communicating providing the sustainability component with the sustainability information regarding the component of the information handling system.

Abstract: The present disclosure generally relates to camera and visitor user interfaces. In some examples, the present disclosure relates to techniques for switching between configurations of a camera view. In some examples, the present disclosure relates to displaying indications of visitors detected by an accessory device of the home automation system. In some examples, the present disclosure relates to displaying a multi-view camera user interface.

Abstract: Some embodiments include an integrated structure having vertically-stacked conductive levels alternating with dielectric levels. A layer over the conductive levels includes silicon, nitrogen, and one or more of carbon, oxygen, boron and phosphorus. In some embodiments the vertically-stacked conductive levels are wordline levels within a NAND memory array. Some embodiments include an integrated structure having vertically-stacked conductive levels alternating with dielectric levels. Vertically-stacked NAND memory cells are along the conductive levels within a memory array region. A staircase region is proximate the memory array region. The staircase region has electrical contacts in one-to-one correspondence with the conductive levels. A layer is over the memory array region and over the staircase region. The layer includes silicon, nitrogen, and one or more of carbon, oxygen, boron and phosphorus.

Abstract: Methods and systems for performing model-less measurements of semiconductor structures based on scatterometry measurement data are described herein. Scatterometry measurement data is processed directly, without the use of a traditional measurement model. Measurement sensitivity is defined by the changes in detected diffraction images at one or more non-zero diffraction orders over at least two different illumination incidence angles. Discrete values of a scalar function are determined directly from measured images at each incidence angle. A continuous mathematical function is fit to the set of discrete values of the scalar function determined at each incidence angle. A value of a parameter of interest is determined based on analysis of the mathematical function. In some embodiments, the scalar function includes a weighting function, and the weighting values associated with weighting function are optimized to yield an accurate fit of the mathematical function to the scalar values.

Abstract: Provided herein are recombinant CTLA-4 binding proteins, which are, inter alia, useful for the treatment of cancer. The recombinant proteins provided herein are, inter alia, capable of binding CTLA-4 proteins on a tumor cell. In a first aspect, there is provided a recombinant CTLA-4 binding protein including (i) a CTLA-4 binding domain; (ii) a CTLA-4 binding domain masking peptide; and (iii) a cleavable peptide linker connecting the CTLA-4 binding domain masking peptide to the CTLA-4 binding domain. In another aspect, there is provided a dimerizing domain covalently attached to the CTLA-4 binding domain, wherein the binding protein domains are bound together.

Abstract: This invention generally relates to the field of somatic gene therapy. The invention provides a nucleic acid construct comprising a transgene encoding a therapeutic protein, a tetracycline-responsive aptazyme sequence, and inverted terminal repeats (ITRs). The nucleic acid construct can be transferred to a subject in need thereof in the form of a viral vector, in particular an adeno-associated virus (AAV) vector. The Tet-responsive aptazyme sequence allows for a tightly controlled expression of the transgene in the subject, thereby avoiding toxic side effects. The nucleic acid construct and the viral vectors comprising same are particularly useful in the treatment of proliferative diseases like cancer.

Abstract: An entertainment system including a removable seat-back display unit and a docking station. The seat-back display unit can include a rotating latch butterfly release mechanism that prevents unauthorized release of the display unit from the docking station. The system can include a three-point attachment system that provides additional protection against accidental detachment of the display unit, and provide safety in the event of partial dislodging. The system can include a current control pin system that ensures that current is not provided from the docking station to the display unit until the respective connectors have been properly engaged. The system can also include a heat dissipation system that employs the docking station to share the heat dissipation load with the display unit.

Abstract: Various implementations disclosed herein include devices, systems, and methods that provide a view of a three-dimensional (3D) environment in which virtual content is presented. For example, an example process may include obtaining virtual content and positioning the virtual content within a view of a 3D environment by determining on-screen content and off-screen content, positioning the on-screen content on a virtual screen within the 3D environment, and positioning off-screen content outside of the virtual screen within the 3D environment. The method may further include presenting the view of the 3D environment including a presentation of the on-screen content on the virtual screen and the off-screen content outside of the virtual screen.

Abstract: The present technology aims at providing a novel type of drug for treating a subject suffering from an inflammatory disease. Specifically, the present technology provides polypeptides comprising at least four immunoglobulin single variable domains (ISVDs), characterized in that at least two ISVDs bind to IL-13 and at least two ISVDs binds to TSLP. The present technology also provides nucleic acids, vectors and compositions.

Abstract: A trailer-based system and related method are described for efficiently transporting, configuring and deploying a power flow control system, including connection to a power transmission line. The system may include preconfigured modules using bolted attachments, hoist rings and a corona ring structure. Standardized clamps are also used. A plurality of power flow control modules is operable while mounted on the trailer. The power flow control modules are configurable to inject reactive power into the power transmission line.

Abstract: There is disclosed a labyrinth seal arrangement for gas turboexpanders and the like which reduces process gas losses. The labyrinth seal includes a plurality of axially spaced seal sets with teeth facing a seal member. A plurality of vent ports in between each seal set permits extraction of gradually lower pressure process gas.

Abstract: A method of making an optical article having a gradient tint and a gradient polarization. The method includes providing an optical element including a coating having at least one alignment zone. A dye composition is contacted with the coating. The dye composition includes at least one of: a dichroic dye, a photochromic-dichroic dye, or a combination thereof to diffuse at least a portion of the dye composition into the coating at a predetermined concentration gradient along at least a portion of the coating to provide the gradient tint and the gradient polarization. A kit for making an optical article having a gradient tint and a gradient polarization. An optical article prepared from a method for making an optical article having a gradient tint and a gradient polarization.

Abstract: There is disclosed a labyrinth seal arrangement for gas turboexpanders and the like which reduces process gas losses. The labyrinth seal includes a plurality of axially spaced seal sets with teeth facing a seal member. A plurality of vent ports in between each seal set permits extraction of gradually lower pressure process gas.

Abstract: In certain embodiments, a system for obtaining ophthalmic information includes an illumination device having an optical fiber; a hyperspectral illumination source; a controller; a modulation device; and an imaging device. The modulation device is configured to receive first source light generated from the hyperspectral illumination source. The first source light includes multiple wavelengths. The modulation device is also configured to modulate each of the wavelengths with a different frequency to generate second source light having multiple frequency modulated wavelengths, and transmit the second source light to an optical fiber, which emits the second source light to contact an eye tissue. The imaging device selects a first frequency associated with a first frequency modulated wavelength and captures light returning from the eye tissue as a result of the first frequency modulated wavelength contacting the eye tissue. The controller determines parameter(s) of the eye tissue based on the return light.

Abstract: In certain embodiments, an optical system for obtaining surgical information includes a probe housing a first optical fiber, a light source, a photoanalyzer, and an optical circulator optically coupled to each of the first optical fiber, the light source, and the photoanalyzer. The optical circulator has a first port configured to receive source light generated from the light source, a second port configured to transmit the source light from the first port to the first optical fiber, and a third port configured to transmit return light in the first optical fiber from the second port to the photoanalyzer. The first optical fiber is configured to emit at least a portion of the source light in the first optical fiber from the probe to contact a body structure, and collect light returning from the body structure as a result of the portion of the source light contacting the body structure.