Patents by Inventor John Pasquale TOSCANO

John Pasquale TOSCANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydropersulfide precursors
    Patent number: 11926580
    Abstract: A hydropersulfide precursor compound having the formula (I): formula (I) as defined in the specification. A process for preparing the hydropersulfide precursor, and a method of using the precursor to generate hydropersulfide are also described.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: March 12, 2024
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: John Pasquale Toscano, Vinayak S. Khodade
  • ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE
    Publication number: 20230242479
    Abstract: Alkylamine-substituted perthiocarbamates capable of controllable release of hydropersulfides (RSSH) and carbonyl sulfide (COS) and their use in treating or preventing ischemia-reperfusion injury are described.
    Type: Application
    Filed: January 25, 2023
    Publication date: August 3, 2023
    Inventors: John Pasquale Toscano, Vinayak S. Khodade
  • Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide
    Patent number: 11584712
    Abstract: Alkylamine-substituted perthiocarbamates capable of controllable release of hydropersulfides (RSSH) and carbonyl sulfide (COS) and their use in treating or preventing ischemia-reperfusion injury are described.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: February 21, 2023
    Assignee: The Johns Hopkins University
    Inventors: John Pasquale Toscano, Vinayak S. Khodade
  • ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE
    Publication number: 20210238134
    Abstract: Alkylamine-substituted perthiocarbamates capable of controllable release of hydropersulfides (RSSH) and carbonyl sulfide (COS) and their use in treating or preventing ischemia-reperfusion injury are described.
    Type: Application
    Filed: February 3, 2021
    Publication date: August 5, 2021
    Inventors: John Pasquale Toscano, Vinayak S. Khodade
  • HYDROPERSULFIDE PRECURSORS
    Publication number: 20210179553
    Abstract: A hydropersulfide precursor compound having the formula (I): formula (I) as defined in the specification. A process for preparing the hydropersulfide precursor, and a method of using the precursor to generate hydropersulfide are also described.
    Type: Application
    Filed: August 30, 2019
    Publication date: June 17, 2021
    Inventors: John Pasquale TOSCANO, Vinayak S. KHODADE