Patents by Inventor John-Paul Jaewoon Yu

John-Paul Jaewoon Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for assessment of neuro-inflammation using magnetic resonance imaging (MRI)
    Patent number: 12268466
    Abstract: A system and method are provided for non-invasively assessing neuro-inflammation in a subject. The method includes acquiring neurite orientation dispersion and density imaging (NODDI) data of the subject and processing the NODDI data to determine an orientation dispersion index (ODI) component of the NODDI data. The method also includes assessing the ODI component against one of a reference of neuro-inflammation or a prior ODI component acquired from the subject to determine one of an acute assessment or a chronic assessment of neuro-inflammation in the subject. The method further includes generating a report indicating the one of an acute assessment or a chronic assessment of neuro-inflammation in the subject.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: April 8, 2025
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventor: John-Paul Jaewoon Yu
  • SYSTEM AND METHOD FOR ANALYZING GENE EXPRESSION USING DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING (MRI)
    Publication number: 20250064337
    Abstract: A system and method are provided for transcriptomic MRI (TMRI) analysis of a subject to determine diagnostic or prognostic information about the subject. The method includes accessing diffusion-weighted MR image data acquired from the subject, processing the diffusion-weighted MR image data using a multi-compartment model, and processing the diffusion-weighted MR image data using a radiomic analysis to generate texture features. The method also includes analyzing the texture features to determine diagnostic or prognostic information about the subject and generating a report communicating the diagnostic or prognostic information about the subject.
    Type: Application
    Filed: August 23, 2023
    Publication date: February 27, 2025
    Inventors: John-Paul Jaewoon Yu, Ajay Paul Singh
  • SYSTEM AND METHOD FOR ASSESSMENT OF NEURO-INFLAMMATION USING MAGNETIC RESONANCE IMAGING (MRI)
    Publication number: 20190365229
    Abstract: A system and method are provided for non-invasively assessing neuro-inflammation in a subject. The method includes acquiring neurite orientation dispersion and density imaging (NODDI) data of the subject and processing the NODDI data to determine an orientation dispersion index (ODI) component of the NODDI data. The method also includes assessing the ODI component against one of a reference of neuro-inflammation or a prior ODI component acquired from the subject to determine one of an acute assessment or a chronic assessment of neuro-inflammation in the subject. The method further includes generating a report indicating the one of an acute assessment or a chronic assessment of neuro-inflammation in the subject.
    Type: Application
    Filed: May 23, 2019
    Publication date: December 5, 2019
    Applicant: Wisconsin Alumni Research Foundation
    Inventor: John-Paul Jaewoon Yu