Patents by Inventor John Pedersen
John Pedersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20050189213Abstract: A reactor for plating a metal onto a surface of a workpiece is set forth. The reactor comprises a reactor bowl including an electroplating solution disposed therein and an anode disposed in the reactor bowl in contact with the electroplating solution. A contact assembly is spaced from the anode within the reactor bowl. The contact assembly includes a plurality of contacts disposed to contact a peripheral edge of the surface of the workpiece to provide electroplating power to the surface of the workpiece. The contacts execute a wiping action against the surface of the workpiece as the workpiece is brought into engagement therewith The contact assembly also including a barrier disposed interior of the plurality of contacts. The barrier includes a member disposed to engage the surface of the workpiece to assist in isolating the plurality of contacts from the electroplating solution.Type: ApplicationFiled: March 21, 2005Publication date: September 1, 2005Inventors: Daniel Woodruff, Kyle Hanson, Thomas Oberlitner, LinLin Chen, John Pedersen, Vladimir Zila
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Publication number: 20040235090Abstract: A desired protein having the formula:Type: ApplicationFiled: October 20, 2003Publication date: November 25, 2004Inventors: Henrik Dalboge, John Pedersen, Thorkild Christensen, Jorli Winnie Ringsted, Torben Ehlern Jessen
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Publication number: 20040047853Abstract: The present invention relates to a substantially pure proenzyme of dipeptidyl peptidase I (pro-DPPI) and mutants thereof. The invention disclosed herein presents novel and fundamentally inventive means of producing substantially pure pro-DPPI in milligrams to gram scale quantities and of selectively purifying unprocessed pro-DPPI from mixtures of pro-DPPI and DPPI. The present invention further relates to biochemical and pharmaceutical applications of pro-DPPI and the generation of monoclonal and polyclonal antibodies against pro-DPPI and the uses thereof.Type: ApplicationFiled: March 10, 2003Publication date: March 11, 2004Inventors: Soren W Dahl, Connie Lauritzen, John Pedersen, Boris Turk
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Publication number: 20040043469Abstract: The present invention relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, modified dipeptidyl peptidase I (DPPI) proteins and DPPI co-complexes. Included in the present invention is a crystal of a dipeptidyl peptidase I (DPPI) and corresponding structural information obtained by X-ray crystallography from rat and human DPPI. In addition, this invention relates to methods for using structure co-ordinates of DDPI, mutants hereof andco-complexes, to design compounds that bind to the active site or accessory binding sites of DPPI and to design improved inhibitors of DPPI or homologues of the enzyme.Type: ApplicationFiled: August 15, 2003Publication date: March 4, 2004Inventors: Johan Gotthardt Olsen, Anders Kadziola, Soren Weis Dahl, Connie Lauritzen, Sine Larsen, John Pedersen, Susan Turk, Marietka Podobnik, Igor Stern
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Publication number: 20010018199Abstract: A desired protein having the formula:Type: ApplicationFiled: October 17, 1997Publication date: August 30, 2001Inventors: HENRIK DALBOGE, JOHN PEDERSEN, THORKILD CHRISTENSEN, JORLI WINNIE RINGSTED, TORBEN EHLERN JESSEN
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Patent number: 5863240Abstract: The present invention relates to an improved blast cleaning apparatus for cleaning coiled wire with abrasive cleaning material. A prior art apparatus for blast cleaning wires comprises an elongated boom provided with annular splitters for longitudinal separation of wire coils and metal lifters for radial separation of wire coils to expose substantially all of the surface of the wires to the abrasive cleaning material. Due to the hardness of the lifters, some abrasive cleaning material becomes embedded in the wire and causes problems with subsequent processing steps. The present invention provides a blast cleaning apparatus having resilient lifters which overcome this and other difficulties. Preferably, the lifters according to the present invention are made of polyurethane and are used in combination with a conventional boom with or without splitters.Type: GrantFiled: February 29, 1996Date of Patent: January 26, 1999Inventor: John A. Pedersen
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Patent number: 5782676Abstract: The present invention relates to an improved lifter for a blast cleaning apparatus for cleaning coiled wire with abrasive cleaning material. A prior art apparatus for blast cleaning wires comprises an elongated boom provided with annular splitters for longitudinal separation of wire coils and metal lifters for radial separation of wire coils to expose substantially all of the surface of the wires to the abrasive cleaning material. Due to the hardness of the lifters, some abrasive cleaning material becomes embedded in the wire and causes problems with subsequent processing steps. The present invention provides a resilient lifter for a blast cleaning apparatus which overcome this and other difficulties. Preferably, the lifters according to the present invention are made of polyurethane and are used in combination with a conventional boom with or without splitters.Type: GrantFiled: November 3, 1997Date of Patent: July 21, 1998Assignee: Blast Cleaning Products Ltd.Inventor: John A. Pedersen
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Patent number: 5783413Abstract: An enzymatic process is presented for producing a desired protein from an amino terminal extended protein by reaction with one or more aminopeptidases, glutamine cyclotransferase and pyroglutamine aminopeptidase.Type: GrantFiled: February 5, 1997Date of Patent: July 21, 1998Assignee: Unizyme Laboratories A/SInventors: John Pedersen, Conni Lauritzen, Mads Thorup Madsen
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Patent number: 5691169Abstract: A desired protein having the formula:A-B-C-Pwhereina) A is Lys or Arg, and B and C are arbitrary amino acids, orb) A is an arbitrary amino acid different from Pro, Lys and Arg, and B and/or C is Pro,is produced from a biosynthetically formed amino acid extended protein having the formula:X-A-B-C-Pwherein A, B, C and P are as defined above, and X is an amino acid sequence with an even number of amino acids, of which the first one, seen from the N-terminal end, is different from Lys and Arg, all other uneven amino acids are different from Pro, Lys and Arg, and all even amino acids are different from Pro, by reaction with the enzyme dipeptidyl aminopeptidase (DAP I). The desired protein is obtained in a pure state. Thus, e.g. hGH without content of Met-hGH may be produced by the process.Type: GrantFiled: March 10, 1995Date of Patent: November 25, 1997Assignee: Novo Nordisk A/SInventors: Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli Winnie Ringsted, Torben Ehlern Jessen
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Patent number: 5679552Abstract: A desired protein having the formula:A--B--C--Pwhereina) A is Lys or Arg, and B and C are arbitrary amino acids, orb) A is an arbitrary amino acid different from Pro, Lys and Arg, and B and/or C is Pro,is produced from a biosynthetically formed amino acid extended protein having the formula:X--A--B--C--Pwherein A, B, C and P are as defined above, and X is an amino acid sequence with an even number of amino acids, of which the first one, seen from the N-terminal end, is different from Lys and Arg, all other uneven amino acids are different from Pro, Lys and Arg, and all even amino acids are different from Pro, by reaction with the enzyme dipeptidyl aminopeptidase (DAP I). The desired protein is obtained in a pure state. Thus, e.g. hGH without content of Met-hGH may be produced by the process.Type: GrantFiled: May 25, 1995Date of Patent: October 21, 1997Assignee: Novo Nordisk A/SInventors: Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli Winnie Ringsted, Torben Ehlern Jessen
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Patent number: 5635604Abstract: A desired protein having the formula:A-B-C-P,wherein (a) A is Lys or Arg, and B and C are arbitrary amino acids, or (b) A is an arbitrary amino acid different from Pro, Lys, and Arg, and B and/or C is Pro is produced from a biosynthetically formed amino-terminally extended protein having the formula:X-A-B-C-P,wherein A, B, C are defined above, and X is an amino acid sequence with an even number of amino acids, of which the first amino acid, seen from the N-terminal end, is different from Lys and Arg, all other am/no acids are different from Pro, Lys and Arg, and all even amino acids are different from Pro, by reaction with the enzyme dipeptidyl aminopeptidase (DAP I). The desired protein is obtained in a pure state. Specifically, P is human growth hormone (hGH). Thus, compositions of hGH may be produced without the presence of Met-hGH.Type: GrantFiled: May 25, 1995Date of Patent: June 3, 1997Assignee: Novo Nordisk A/SInventors: Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli W. Ringsted, Torben E. Jessen
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Patent number: 5633352Abstract: A desired protein having the formula:A-B-C-Pwhereina) A is Lys or Arg, and B and C are arbitrary amino acids, orb) A is an arbitrary amino acid different from Pro, Lys and Arg, and B and/or C is Pro,is produced from a biosynthetically formed amino acid extended protein having the formula:X-A-B-C-Pwherein A, B, C and P are as defined above, and X is an amino acid sequence with an even number of amino acids, of which the first one, seen from the N-terminal end, is different from Lys and Arg, all other uneven amino acids are different from Pro, Lys and Arg, and all even amino acids are different from Pro, by reaction with the enzyme dipeptidyl aminopeptidase (DAP I). The desired protein is obtained in a pure state. Thus, e.g. hGH without content of Met-hGH may be produced by the process.Type: GrantFiled: March 10, 1995Date of Patent: May 27, 1997Assignee: Novo Nordisk A/SInventors: Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli W. Ringsted, Torben E. Jessen
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Patent number: 5618697Abstract: A process for producing ripe human growth hormone is described which comprises introducing into bacteria a recombinant DNA vector comprising a DNA sequence encoding an amino-terminal extended human growth hormone which amino-terminal extension has a negatively charged amino acid sequence and has an even number of amino acids, growing the bacteria such that the amino-terminal extended human growth is expressed, separating the amino-terminal extended human grown hormone from contaminants, cleaving the amino-terminal extension with dipeptidyl aminopeptidase I to obtain ripe human growth hormone and isolating the ripe human growth hormone produced.Type: GrantFiled: January 13, 1995Date of Patent: April 8, 1997Assignee: Novo Nordisk A/SInventors: Henrik Dalb.o slashed.ge, John Pedersen, Thorkild Christensen, J.o slashed.rli W. Ringsted, Torben E. Jessen
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Patent number: 5356798Abstract: In a method for effecting an increased expression in serum-free medium of recombinant proteins in a host cell being able to express said protein said host is cultured in a serum-free medium comprising an egg yolk fraction being free of lipoprotein and lipids so as to express said protein. Also the use of an egg yolk fraction being free of lipoprotein and lipids for increasing the expression of recombinant proteins in a host cell being able to express said protein in a serum-free cell growth medium is disclosed.Type: GrantFiled: April 23, 1993Date of Patent: October 18, 1994Assignee: Novo Nordisk A/SInventors: Leif Kongerslev, John Pedersen
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Patent number: 4077508Abstract: An enclosed hanger bearing suitable for use under severe operating conditions is disclosed. The bearing is completely sealed to prevent the entry of abrasive materials. The bearing has an adaptor plate for engaging augers which are supported by the bearing from an overhead support. A combination of felt and magnetic strip seals are employed to prevent entry of abrasive into the bearing which is permanently lubricated.Type: GrantFiled: October 15, 1976Date of Patent: March 7, 1978Assignee: Wheelabrator-Frye Inc.Inventor: John A. Pedersen
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Patent number: 4070799Abstract: A finger seal is disclosed for use in conjunction with shot blasting operations. The seal is formed of polyurethane or similar materials which are resistant to wear from shot blasting. The seals are provided with a plurality of longitudinal reinforcing ribs to increase their strength and effectiveness in preventing the escape of shot from an enclosure.Type: GrantFiled: March 9, 1977Date of Patent: January 31, 1978Assignee: Wheelabrator-Frye Inc.Inventor: John A. Pedersen
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Patent number: 4031111Abstract: Macrocyclic imines useful as complexing agents for ionic metal compounds characterized by a macrocyclic ring or rings of carbon and hetero-atoms totaling 14-60 ring atoms, at least one hetero-atom being nitrogen and the remainder being oxygen, each hetero-atom in the ring being separated from adjoining hetero-atoms by links of 2 or 3 carbon atoms. The macrocyclic ring or rings are fused to 1-4 carbocyclic rings. The macrocyclic rings or substituted derivatives of them can be monocyclic, bicyclic, or bridged by a carbon, or carbon-hetero-atom chain.Type: GrantFiled: September 6, 1974Date of Patent: June 21, 1977Assignee: E. I. Du Pont de Nemours and CompanyInventors: Charles John Pedersen, Marilyn H. Bromels
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Patent number: 3998838Abstract: A complex of (A) an organic sulfur-bearing compound and (B) a macrocyclic polyether having a 15-60 carbon and oxygen ring and 1-4 fused carbocyclic rings; the ratio of A:B being about 1:1 to about 6:1. The complex can be used as a curing component for vulcanization of sulfur-curable elastomers.Type: GrantFiled: November 5, 1974Date of Patent: December 21, 1976Assignee: E. I. Du Pont de Nemours and CompanyInventor: Charles John Pedersen