Abstract: A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.

Abstract: Expandable occlusive plugs and methods of using them are disclosed. The devices generally include a tubular body bearing multiple slits defining leaves, which expand radially outward when the ends of the device are brought toward one another.

Abstract: Embolic material delivery devices and methods of using them are disclosed. An example embolic material delivery assembly includes an outer member having a lumen extending therein and a distal end region, an inner member disposed within the lumen of the outer member, wherein the inner member includes a first lumen extending therein. The embolic material delivery assembly also includes a first embolic material extending within the first lumen of the inner member, the embolic material having a first distal end region. The embolic material delivery assembly also includes an anchor disposed within the lumen of the outer member, the anchor having a first attachment region. Further, the first distal end region of the first embolic material is coupled to the first attachment region of the anchor.

Abstract: Loading tools for use with medical devices are disclosed. An example loading tool may be suitable for use with a drug-coated expandable medical device. The loading tool may include a tubular sleeve having a distal end region, a proximal end region, and a lumen extending therethrough. The distal end region may include a reduced distal tip designed to interact with a hemostasis valve having a resilient seal member.

Abstract: A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.

Abstract: A medical device may be a loading tool including a tubular member having a lumen extending therethrough. The tubular member may include a distal portion and a proximal portion. The proximal portion of the tubular member may include a flexible member. The flexible member may be axially and radially adjustable between a first configuration and a second configuration. The distal portion of the tubular member may be configured to engage a valve, and the valve may be in communication with a lumen of an elongated medical device.

Abstract: A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.

Abstract: Embolic material delivery devices and methods of using them are disclosed. An example embolic material delivery assembly includes an outer member having a lumen extending therein and a distal end region, an inner member disposed within the lumen of the outer member, wherein the inner member includes a first lumen extending therein. The embolic material delivery assembly also includes a first embolic material extending within the first lumen of the inner member, the embolic material having a first distal end region. The embolic material delivery assembly also includes an anchor disposed within the lumen of the outer member, the anchor having a first attachment region. Further, the first distal end region of the first embolic material is coupled to the first attachment region of the anchor.

Abstract: Loading tools for use with medical devices are disclosed. An example loading tool may be suitable for use with a drug-coated expandable medical device. The loading tool may include a tubular sleeve having a distal end region, a proximal end region, and a lumen extending therethrough. The distal end region may include a reduced distal tip designed to interact with a hemostasis valve having a resilient seal member.

Abstract: Loading tools for use with medical devices are disclosed. An example loading tool may include a tubular sleeve having a proximal end region, a distal end region, and a lumen. The distal end region may be designed to be engaged with a resilient seal member of a hemostasis valve so that a medical device disposed within the lumen can be passed through the resilient seal member. The tubular sleeve may include a tube wall. At least a portion of the tube wall may overlap to define an overlapping region.

Abstract: A clip for reducing a dimension of an opening in tissue may include a continuous member having a plurality of legs and a plurality of preformed bends connecting adjacent legs, wherein the plurality of legs form: a first group having two protrusions; a second group having two protrusions; and a third group having two protrusions, wherein each protrusion of each group includes two legs of the continuous member and a corresponding preformed bend connecting the two legs, and each protrusion of each group extends from a region adjacent a first end of the clip to a region adjacent a second end of the clip.

Abstract: Delivery systems for liquid embolics and methods of using them are disclosed. The devices generally include a catheter and one or more retention elements to limit migration of the liquid embolic to non-target sites.

Abstract: Expandable occlusive plugs and methods of using them are disclosed. The devices generally include a tubular body bearing multiple slits defining leaves, which expand radially outward when the ends of the device are brought toward one another.

Abstract: The present disclosure relates to embolic coils that eliminate kick-back into a parent vessel by providing a proximal end that retracts following deployment within the vasculature. Also disclosed are methods of making such coils, delivery systems that comprise such coils, and methods of delivering such coils to a patient.

Abstract: The present disclosure provides systems and methods for actively releasing embolic coils within a body lumen of a patient.

Abstract: A drug delivery device that uses centrifugal force to deliver a drug to a body lumen wall. The drug delivery device comprises an impeller that includes an impeller shaft; an impeller head at the distal end of the impeller shaft; a drug lumen; an impeller housing; and a housing shaft attached to the impeller housing. In use, the drug is advanced along the drug lumen to the impeller head; at least the impeller head is rotated so that when drug exits the drug lumen, the centrifugal force of the rotating impeller causes the drug to move radially outward from the drug delivery device, towards and into the body lumen wall.

Abstract: A Universal Serial Bus (USB) dongle may include an optical transceiver having a USB inter face for engagement to an electronic device such as a laptop computer or other USB-configured device. The USB dongle may include a converter or buffering, isolation, modulation or amplification circuitry. The USB dongle sends and receives data signals which may be carried upon an optical transmission as generated by an LED light source which in turn is in communication with a host device such as a network processor. The USB dongle may also include operational amplifiers (op-amps) and transistor amplifiers.

Abstract: An LED light and communication system includes one or more optical transceivers that have a light support having a plurality of light emitting diodes and one or more photodetectors attached thereto, and a processor in communication with the light emitting diodes and the one or more photodetectors. The processor is constructed and arranged to generate a communication signal. The one or more optical transceivers are engaged to a lighting fixture within a building. The one or more optical transceivers are constructed and arranged to communicate with a name tag.

Abstract: A Universal Serial Bus (USB) dongle may include an optical transceiver having a USB inter face for engagement to an electronic device such as a laptop computer or other USB-configured device. The USB dongle may include a converter or buffering, isolation, modulation or amplification circuitry. The USB dongle sends and receives data signals which may be carried upon an optical transmission as generated by an LED light source which in turn is in communication with a host device such as a network processor. The USB dongle may also include operational amplifiers (op-amps) and transistor amplifiers.

Abstract: The present invention provides a catheter balloon having an advantageous cone design. In particular, the catheter balloon has at least one cone section with a volume in mm3 such that, when the ratio of one cone volume to the transverse cross-sectional area in mm2 of the inflated median section is at least about 2.1 mm. In certain applications, the advantageous cone design can assist in the preferential expansion of the cone sections prior to any significant expansion of the median section. The balloon can thus advantageously be utilized as a component of a balloon catheter or prosthesis delivery system, also provided via the present invention. When so utilized, the inventive balloon can assist in reducing any shifting of the balloon and/or prosthesis during inflation or delivery, respectively. Methods of utilizing the balloon catheters in dilation procedures, as well as the prosthesis delivery systems to deliver prosthesis, are also provided.