Abstract: The disclosed computer-implemented method may include establishing a virtual boundary for a virtual-world environment in reference to a real-world environment, and determining whether the virtual boundary requires a correction. The method may include providing, in response to determining that the virtual boundary requires the correction, and alert and, in response to the alert, receiving a request from a user to modify the virtual boundary. The method may further include monitoring, in response to the request from the user, an orientation of a direction indicator to generate orientation data, and modifying the virtual boundary based on the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The disclosed computer-implemented method may include establishing a virtual boundary for a virtual-world environment in reference to a real-world environment, and determining whether the virtual boundary requires a correction. The method may include providing, in response to determining that the virtual boundary requires the correction, and alert and, in response to the alert, receiving a request from a user to modify the virtual boundary. The method may further include monitoring, in response to the request from the user, an orientation of a direction indicator to generate orientation data, and modifying the virtual boundary based on the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The disclosed computer-implemented method may include establishing a virtual boundary for a virtual-world environment in reference to a real-world environment, and determining whether the virtual boundary requires a correction. The method may include providing, in response to determining that the virtual boundary requires the correction, and alert and, in response to the alert, receiving a request from a user to modify the virtual boundary. The method may further include monitoring, in response to the request from the user, an orientation of a direction indicator to generate orientation data, and modifying the virtual boundary based on the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Epileptic seizures are difficult to diagnose and are often difficult to distinguish from several conditions with similar presentations, and therefore, diagnosis of seizures is often a long, expensive, and unreliable process. This invention provides biomarkers for identifying seizures and epilepsy, assays for measuring and assessing biomarker concentration, predictive models based on biomarkers and computer systems for detecting, assessing and diagnosing phasic and tonic changes associated with seizures and epilepsy in all clinical and healthcare settings. Diagnostic methods, kits and predictive models provided herein provide quantitative and/or qualitative assessment in order to allow patients to proceed immediately to diagnostic and/or treatment protocols, and assess therapeutic treatment effectiveness.

Abstract: Epileptic seizures are difficult to diagnose and are often difficult to distinguish from several conditions with similar presentations, and therefore, diagnosis of seizures is often a long, expensive, and unreliable process. This invention provides biomarkers for identifying seizures and epilepsy, assays for measuring and assessing biomarker concentration, predictive models based on biomarkers and computer systems for detecting, assessing and diagnosing phasic and tonic changes associated with seizures and epilepsy in all clinical and healthcare settings. Diagnostic methods, kits and predictive models provided herein provide quantitative and/or qualitative assessment in order to allow patients to proceed immediately to diagnostic and/or treatment protocols, and assess therapeutic treatment effectiveness.

Abstract: The disclosed computer-implemented method may include establishing a virtual boundary for a virtual-world environment in reference to a real-world environment, and determining whether the virtual boundary requires a correction. The method may include providing, in response to determining that the virtual boundary requires the correction, and alert and, in response to the alert, receiving a request from a user to modify the virtual boundary. The method may further include monitoring, in response to the request from the user, an orientation of a direction indicator to generate orientation data, and modifying the virtual boundary based on the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The disclosed computer-implemented method may include receiving an indication of a reference elevation representing a plane of a real-world environment and establishing, with respect to the reference elevation, a virtual boundary for a virtual-world environment. The method may include receiving a request from a user to modify the virtual boundary and in response to the request from the user, monitoring an orientation of a direction indicator to generate orientation data. The method may also include modifying the virtual boundary based on the reference elevation and the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: In certain embodiments, a headpiece 101 may contain the functional components described above integrated therein, and the headpiece may be releasably matable, The present invention relates to systems and methods for patient monitoring and intervention to prevent sudden unexpected death, as may occur in patients with epilepsy (SUDEP) or in infants as part of SUID, SIDS and/or suffocation. More specifically, the present invention provides a wearable device configured for monitoring a wearer and/or his environment, identifying and/or assessing death risk to the wearer, initiating communications to a caregiver that might provide an intervention or other treatment, and/or itself performing an action acting as an intervention to prevent death of the wearer. The wearable device includes particular sensors for gathering data from the wearer and/or the wearer's environment. Optionally, the wearable device may further include stimulators for delivering a death-preventing intervention stimulus to the wearer.

Abstract: The disclosed computer-implemented method may include receiving an indication of a baseline elevation representing a base plane of a real-world environment, receiving a request via a user device to initiate a boundary definition state, monitoring an elevation and an orientation of the user device during manipulation to generate elevation data and orientation data during the boundary definition state, and defining a virtual boundary in a virtual-world environment based on the baseline elevation, the elevation data, and the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Epileptic seizures are difficult to diagnose and are often difficult to distinguish from several conditions with similar presentations, and therefore, diagnosis of seizures is often a long, expensive, and unreliable process. This invention provides biomarkers for identifying seizures and epilepsy, assays for measuring and assessing biomarker concentration, predictive models based on biomarkers and computer systems for detecting, assessing and diagnosing phasic and tonic changes associated with seizures and epilepsy in all clinical and healthcare settings. Diagnostic methods, kits and predictive models provided herein provide quantitative and/or qualitative assessment in order to allow patients to proceed immediately to diagnostic and/or treatment protocols, and assess therapeutic treatment effectiveness.

Abstract: The disclosed computer-implemented method may include receiving an indication of a reference elevation representing a plane of a real-world environment and establishing, with respect to the reference elevation, a virtual boundary for a virtual-world environment. The method may include receiving a request from a user to modify the virtual boundary and in response to the request from the user, monitoring an orientation of a direction indicator to generate orientation data. The method may also include modifying the virtual boundary based on the reference elevation and the orientation data. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: A system and method for controlling a boiler comprising a microcomputer operatively connected to a microcontroller wherein the microcontroller is configured to provide flame safeguard operations and the microcomputer is configured to provide operating control instructions to the microcontroller. The boiler control system may operate either in a stand-alone, cascade master or cascade slave configuration.

Abstract: A seat belt retractor (10) having a frame with sides (14, 16) and a cover associated with at least one side, an inertial sensor (30) positioned between the at least one side of the frame and the cover, a seal located between the cover and the frame side to prevent contaminants from entering a space about the inertial sensor, the inertia sensor including a movable mass (34) and a magnet (36) spaced from the mass (34) to create a magnetic force upon the mass (34) preventing the magnet from moving excessively if the retractor is subject to predetermined levels of vibration.

Abstract: Epileptic seizures are difficult to diagnose and are often difficult to distinguish from several conditions with similar presentations, and therefore, diagnosis of seizures is often a long, expensive, and unreliable process. This invention provides biomarkers for identifying seizures and epilepsy, assays for measuring and assessing biomarker concentration, predictive models based on biomarkers and computer systems for detecting, assessing and diagnosing phasic and tonic changes associated with seizures and epilepsy in all clinical and healthcare settings. Diagnostic methods, kits and predictive models provided herein provide quantitative and/or qualitative assessment in order to allow patients to proceed immediately to diagnostic and/or treatment protocols, and assess therapeutic treatment effectiveness.

Abstract: A system and method for controlling a boiler comprising a microcomputer operatively connected to a microcontroller wherein the microcontroller is configured to provide flame safeguard operations and the microcomputer is configured to provide operating control instructions to the microcontroller. The boiler control system may operate either in a stand-alone, cascade master or cascade slave configuration.

Abstract: A system and method for controlling a boiler comprising a microcomputer operatively connected to a microcontroller wherein the microcontroller is configured to provide flame safeguard operations and the microcomputer is configured to provide operating control instructions to the microcontroller. The boiler control system may operate either in a stand-alone, cascade master or cascade slave configuration.

Abstract: The present relates to methods for detecting DNA damage in subjects treated with an ATR inhibitor. More specifically, this invention relates to a method for measuring changes in levels of ?H2AX and/or pChk1Ser345 in, e.g., surrogate tissue cells, following ex vivo stimulation with a DNA damaging agent.

Abstract: A seat belt retractor (10) having a frame with sides (14, 16) and a cover associated with at least one side, an inertial sensor (30) positioned between the at least one side of the frame and the cover, a seal located between the cover and the frame side to prevent contaminants from entering a space about the inertial sensor, the inertia sensor including a movable mass (34) and a magnet (36) spaced from the mass (34) to create a magnetic force upon the mass (34) preventing the magnet from moving excessively if the retractor is subject to predetermined levels of vibration.

Abstract: A system and method for controlling a boiler comprising a microcomputer operatively connected to a microcontroller wherein the microcontroller is configured to provide flame safeguard operations and the microcomputer is configured to provide operating control instructions to the microcontroller. The boiler control system may operate either in a stand-alone, cascade master or cascade slave configuration.

Abstract: The present relates to methods for detecting DNA damage in subjects treated with an ATR inhibitor. More specifically, this invention relates to a method for measuring changes in levels of ?H2AX and/or pChk1Ser345 in, e.g., surrogate tissue cells, following ex vivo stimulation with a DNA damaging agent.