Patents by Inventor John Puisis

John Puisis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250170066
    Abstract: The present disclosure generally relates to the methods of treating solid tumors using negatively charged particles.
    Type: Application
    Filed: February 27, 2023
    Publication date: May 29, 2025
    Inventors: John Puisis, Adam Elhofy, Michael Boyne, Joseph Podojil, Tushar Murthy
  • Publication number: 20240197866
    Abstract: The present disclosure relates, in general to methods of treating peanut allergy using nanoparticles encapsulating peanut antigens to induce antigen-specific tolerance.
    Type: Application
    Filed: April 15, 2022
    Publication date: June 20, 2024
    Inventors: John Puisis, James Herrmann, Michael Boyne, Adam Elhofy, Joseph Podojil, Greta Wodarcyk
  • Publication number: 20240201187
    Abstract: The present application relates, in general, to methods for tracking the induction of and long-term maintenance of antigen specific immune tolerance during administration of an antigen specific immune tolerizing therapy, such as a TIMP.
    Type: Application
    Filed: April 15, 2022
    Publication date: June 20, 2024
    Inventors: John Puisis, James Herrmann, Michael Boyne, Adam Elhofy, Joseph Podojil, Greta Wodarcyk
  • Publication number: 20230338576
    Abstract: The present invention provides compositions comprising tolerizing immune modified particles (TIMPs) and methods for using and making said TIMPs. In particular, carrier polymer is covalently conjugated with antigenic peptide before particle formation, which allows for exquisite control of particle size and antigen encapsulation (e.g., for use in eliciting induction of immunological tolerance).
    Type: Application
    Filed: October 24, 2022
    Publication date: October 26, 2023
    Inventors: Ryan Pearson, Daniel Getts, John Puisis, James Herrmann, Lonnie D. Shea
  • Patent number: 11510996
    Abstract: The present invention provides compositions comprising tolerizing immune modified particles (TIMPs) and methods for using and making said TIMPs. In particular, carrier polymer is covalently conjugated with antigenic peptide before particle formation, which allows for exquisite control of particle size and antigen encapsulation (e.g., for use in eliciting induction of immunological tolerance).
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: November 29, 2022
    Assignees: COUR PHARMACEUTICALS DEVELOPMENT COMPANY INC., THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Ryan Pearson, Daniel Getts, John Puisis, James Herrmann, Lonnie D. Shea
  • Patent number: 11045492
    Abstract: The current invention involves the administration of negatively charged particles, such as polystyrene, PLGA, or diamond particles, to subjects to ameliorate inflammatory immune responses. Additionally, the present invention describes methods of treating inflammatory diseases by administering these same negatively charged particles.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: June 29, 2021
    Assignee: onCour Pharma, Inc.
    Inventor: John Puisis
  • Publication number: 20190282707
    Abstract: The present invention provides compositions comprising tolerizing immune modified particles (TIMPs) and methods for using and making said TIMPs. In particular, carrier polymer is covalently conjugated with antigenic peptide before particle formation, which allows for exquisite control of particle size and antigen encapsulation (e.g., for use in eliciting induction of immunological tolerance).
    Type: Application
    Filed: December 22, 2016
    Publication date: September 19, 2019
    Inventors: Ryan Pearson, Daniel R. Getts, John Puisis, James Herrmann