Abstract: An MNP machine provides a bias field consisting of a low frequency alternating magnetic field and possibly a static magnetic field to a volume in possibly different directions; RF drive coils driven at an FMR/EPR frequency of MNPs in the bias field, and pickup coils or magnetometers measuring the magnetization induced in the MNPs by the bias fields and possibly the RF absorption. The computer derives MNP MPS/MSB spectra, magnetic particle images, or heats the MNPs using the EPR/FMR frequency field. A method of imaging or localizing the MNPs includes applying a magnetic field gradient; applying RF at an EPR/FMR frequency of the MNPs; sweeping magnetic bias field strength or RF frequency to sweep a resonance surface; applying RF at the EPR/FMR frequency, observing EPR/FMR resonances; rotating the magnetic bias field relative to the subject and resweeping the surface; and reconstructing a three-dimensional distribution of MNPs.

Abstract: Disclosed are assays for ultra-fast exponential isothermal amplification of nucleic acids. The assays can improve target detection specificity by using three adjacent binding sites on the target sequence, compared to just one trigger sequence in conventional EXPAR, to initiate the exponential amplification reaction. Amplification of an EXPAR trigger sequence can be carried out via a two-stage process, wherein a first stage achieves linear amplification of the trigger sequence upon successful detection of three adjacent binding sites specified on the target nucleic acid, followed by a second stage that achieves subsequent exponential amplification.

Abstract: Certain Cas9 molecules are capable of discriminately cleaving nucleic acid based upon its epigenetic pattern. These molecules can be either naturally occurring or engineered. They can be used to diagnose and treat disease.

Abstract: Ionizable compounds, and compositions and methods of use thereof. The ionizable compounds can be used for making nanoparticle compositions for use in biopharmaceuticals and therapeutics. More particularly, the compounds, compositions and methods are to provide nanoparticles to encapsulate active agents, such as nucleic acid agents, and to deliver and distribute the active agents to cells, tissues, organs, and subjects.

Abstract: This invention relates to a polymeric pipe obtained by a peroxide crosslinking process. The pipe is formed from a composition comprising a polyolefin structural polymer, a peroxide initiator in an amount of from about 0.2% to about 5% by weight, and a co-agent in an amount of from about 0.02% to about 5% by weight. The co-agent comprises at least two reactive carbon-carbon double bonds. The invention also relates to methods of forming said pipes. The invention also relates to the use of a co-agent in a composition to reduce bubble formation in a peroxide crosslinking process. The invention also relates to the use of such polymeric pipes for the transport of water.

Abstract: The present invention is directed towards curable film-forming compositions comprising metal particles; an alkaline earth metal compound comprising an alkaline earth metal oxide, an alkaline earth metal carbonate, an alkaline earth metal hydroxide, an alkaline earth metal sulfate, an alkaline earth metal monocarboxylate, an alkaline earth metal phosphate, or combinations thereof; and an organic film-forming binder. Also disclosed are methods of making curable film-forming compositions, methods of coating substrates, and coated substrates resulting therefrom.

Abstract: A method is provided for synthesizing bio-based LPG from renewable sources via a bio-based synthetic gas feedstock, using a solvent absorption process and a solid adsorption process for recovering LPG in high yield while providing for high recovery and reuse, with low pressure drop, of unreacted synthesis gas components.

Abstract: Present embodiments relate to an insulated container. More particularly, but without limitation, the present embodiments relate to an insulated container with built-in wireless audio for communication and audio playback from a smart device for audio playback.

Abstract: A first seat comprising a leg support for a user of a separate second seat, the leg support mounted relative to the first seat and adjustably moveable between a stowed position in which the leg support is received against a rear side of the first seat and any one of a plurality of deployed positions including at least a calf-and-foot-support position, and a foot-support position, via a continuous recliner.

Abstract: A helmet liner for a helmet shell includes a peripheral wall configured to abut an inner surface of the helmet shell, and a bonnet configured to receive a head of a wearer. The bonnet is coupled to the peripheral wall and configured to be spaced from the inner surface of the helmet shell. The bonnet is configured to undergo tensile deformation in response to an impact event occurring at the helmet shell.

Abstract: An access system adapted for accessing a desired location within a patient's vasculature includes an outer catheter such as a guide extension catheter and an inner catheter such as a dilator. The outer catheter includes an outer catheter push rod, an outer catheter sheath extending distally from the outer catheter push rod, and a first engagement feature disposed within a distal region of the outer catheter sheath. The inner catheter includes an inner catheter push rod, an inner catheter body extending distally from the inner catheter push rod, and a second engagement feature disposed within a proximal region of the inner catheter body, the second engagement feature adapted to releasably engage the first engagement feature.

Abstract: The systems and methods disclosed herein provide for the efficient separation of gas from fluid comprising liquid. In particular, gas separator systems and methods for use in bioreactor systems and operations are disclosed herein providing an efficient means to remove gaseous waste products, unreacted gaseous substrates, and or inert gas from broth of the biological fermentation of carbon substrates using a microorganism biocatalyst.

Abstract: Systems and methods for operating phased arrays are described. A circuit can receive an index associated with an antenna among a plurality of antennas in a phased array. The circuit can use the index to identify at least a phase value and a gain value of a known beam. The circuit can receive at least one static configuration of the antenna and at least one beam transformation parameter. The circuit can transform, based on the at least one beam transformation parameter and the at least one static configuration, the phase and gain values of the known beam into phase and gain values of a desired beam. The circuit can map the phase value of the desired beam to a phase shifter setting of the antenna and the gain value of the desired beam to a variable gain amplifier setting of the antenna to generate the desired beam.

Abstract: A network-based manufacturing system for electronic devices includes a work cell, a warehouse having a plurality of storage bins for holding electronic components, and a shuttle for moving the electronic components from the plurality of storage bins to the work cell. In response to receiving a request to build an electronic device, the shuttle robotically transports electronic components from the warehouse to the work cell and the electronic device is assembled within the work cell. A work cell includes a framework having of a plurality of support beams; a plurality of pincers moveably coupled to the framework; a first scaffold base coupled to the framework; a plurality of motors coupled to the framework or pincers. The pincers are capable of manipulating and assembling the electronic components. Methods for use of the system and work cell are used to assemble, prototype, operate, or test electronic device or circuits.

Abstract: A layered reporting system for an attraction may include a primary and secondary wireless communication network that are separate from one another. Components of an attraction environment, such as augmented reality/virtual reality headsets and a ride vehicle having a controller, may generate operation data of the attraction. The components of the systems may also include communication circuitry that communicates a first subset of the operation data to the primary wireless network. A second subset of the operation data is communicated via a secondary wireless network having a bandwidth higher than the primary wireless network.

Abstract: The disclosed technology provides a system and method for correlating events from a single application run in a cloud communications network using session identifiers uniquely identifying a communication session, and event identifiers uniquely identifying events in network elements of the cloud communication network. A data manager of the cloud communications network maps common fields and event-specific fields of network element event records to common fields and generic fields of a data warehouse based on the event type of the event to be recorded.

Abstract: A system for utilizing push alert notifications resident in an auto-dialer is provided. The auto-dialer may include a notification/dialing list of push alert notification recipients, an outbound orchestrator utility for receiving a list of the recipients, and a notification service utility. The outbound orchestrator utility may initiate a push alert notification for a member including instructions to send the push alert notification to the notification service utility, and displaying an actionable viewing screen that prompts the member to accept the scheduled time or to schedule a different time. When accepted, a selection is received that accepts the scheduled time for the future call and transmits a confirmation instruction to execute the scheduled call. When the selection declines the scheduled time for the call and re-schedules a new time for the future call, the instructions transmit an instruction to the auto-dialer to execute the future telephone call at the new time.

Abstract: A cable pulling system and associated method are shown. Examples include positioning joints that allows a pulling boom to move up or down and side to side, while maintaining alignment of a pulling cable between pulleys. Example methods include positioning a pulling boom within a conduit box and pulling an electrical cable through a conduit into the conduit box.

Abstract: A computer method and system determine the reactive resources to be switched to keep voltage at key points in a power grid within their allowed high and low limits. The method periodically runs power flow for each of plural time intervals from a current time interval to a future time interval. Asynchronously and in concert with running the power flow, the method periodically formulates and solves a representative mixed integer linear programming (MILP) optimization problem for maintaining voltage within limits of interest, resulting in an optimal reactive resource switching solution. Based on the optimal reactive resource switching solution, the method provides at least one output toward switching in/out reactive resources of a subject power grid. The method and system achieve real-time, multi-interval optimal reactive power dispatching.

Abstract: Disclosed herein are systems and methods for energy management. A system, such as a vehicle, includes a plurality of energy storage units that include a supercapacitor and an electrochemical battery. The system includes an energy controller that tracks historical power draw from the plurality of energy storage units over time in power tracking data, and that identifies a power draw based on the power tracking data. The energy controller switches between a first configuration and a second configuration based on the identified power draw. The first configuration is configured for drawing power from the electrochemical battery and disconnecting from the supercapacitor, while wherein the second configuration is configured for drawing power from the supercapacitor and disconnecting from the electrochemical battery.