Patents by Inventor John R. Adler, Jr.

John R. Adler, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8747292
    Abstract: Radiosurgical techniques and systems treat behavioral disorders (such as depression, Obsessive-Compulsive Disorder (“OCD”), addiction, hyperphagia, and the like) by directing radiation from outside the patient toward a target tissue within the patient's brain, typically without imposing surgical trauma. The target will often be included in a neural circuit associated with the behavioral disorder. A cellularly sub-lethal dose of the radiation may be applied and the radiation can mitigate the behavioral disorder, obesity, or the like, by modulating the level of neural activity within the target and in associated tissues. Hypersensitive and/or hyperactive neuronal tissue may be targeted, with the radiation downwardly modulating hyperactive neuronal activity. By down-regulating the activity of a target that normally exerts negative feedback or a limiting effect on a relevant neural circuit, the activity of the circuit may be increased.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: June 10, 2014
    Inventors: M. Bret Schneider, John R. Adler, Jr.
  • Publication number: 20140155677
    Abstract: Medical systems, devices, and methods provide improved radiosurgical techniques for treatment of anxiety disorders (such as Post-Traumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), Panic Disorder, Social Phobia, Specific Phobia, and the like). Radiation can be directed from a radiation source outside the patient toward a target tissue deep within the patient's brain using a stereotactic radiosurgical platform, typically without having to impose the surgical trauma associated with accessing deep brain tissues. The target will often include at least a portion of the amygdala, with exemplary treatments being directed to targets that are limited to a sub-region of the amygdala. Rather than applying sufficient radiation to kill the neural tissue within the target, a cellularly sub-lethal dose of the radiation may be applied.
    Type: Application
    Filed: May 22, 2013
    Publication date: June 5, 2014
    Inventors: M. Bret Schneider, John R. Adler, JR.
  • Publication number: 20140121494
    Abstract: A method for targeting. The method includes determining skin characteristics in a region of a patient. An in-treatment optical scan is performed on a region of a patient, wherein the in-treatment optical scan comprises a near infrared (NIR) energy source. A plurality of detected signals is detected from the optical scan. The skin characteristics are filtered out from the plurality of detected signals. Skeletal anatomy positioning associated with the region is determined from the plurality of signals that is filtered.
    Type: Application
    Filed: October 2, 2013
    Publication date: May 1, 2014
    Applicant: Varian Medical Systems, Inc.
    Inventors: John R. ADLER,, JR., Agam SHARDA
  • Publication number: 20140121527
    Abstract: A method for measuring skin thickness. The method includes at a first 3D point on an outer surface of a patient, exposing the first point to near infrared (NIR) energy from an NIR source. The method includes measuring reflected energy emanating near the first 3D point, or beam incident point. The method includes determining a pattern of the reflected energy based on a distance from a center of the reflected energy, wherein the center is approximated by the first 3D point. The method includes determining a skin thickness measurement based on the pattern.
    Type: Application
    Filed: September 27, 2013
    Publication date: May 1, 2014
    Applicant: Varian Medical Systems, Inc.
    Inventors: John R. ADLER, JR., Ralf BRUDER, Floris ERNST, Achim SCHWEIKARD
  • Publication number: 20130184511
    Abstract: Radiosurgical techniques and systems treat behavioral disorders (such as depression, Obsessive-Compulsive Disorder (“OCD”), addiction, hyperphagia, and the like) by directing radiation from outside the patient toward a target tissue within the patient's brain, typically without imposing surgical trauma. The target will often be included in a neural circuit associated with the behavioral disorder. A cellularly sub-lethal dose of the radiation may be applied and the radiation can mitigate the behavioral disorder, obesity, or the like, by modulating the level of neural activity within the target and in associated tissues. Hypersensitive and/or hyperactive neuronal tissue may be targeted, with the radiation downwardly modulating hyperactive neuronal activity. By down-regulating the activity of a target that normally exerts negative feedback or a limiting effect on a relevant neural circuit, the activity of the circuit may be increased.
    Type: Application
    Filed: December 7, 2012
    Publication date: July 18, 2013
    Inventors: M. Bret Schneider, John R. Adler, JR.
  • Publication number: 20130144104
    Abstract: A radiation system includes a support, a capsule rotatably coupled to the support, a radiation source movably coupled to the capsule, wherein the radiation source is configured to provide a treatment radiation beam, and is capable of being turned on or off in response to a control signal, and a collimator located next to the radiation source, wherein the capsule defines a space for accommodating a portion of a patient, and includes a shielding material for attenuating radiation resulted from an operation of the radiation source, and wherein the shielding material is configured to limit a radiation exposure level to 5 mR/hr or less within 3 meters from an isocenter.
    Type: Application
    Filed: December 2, 2011
    Publication date: June 6, 2013
    Applicant: VARIAN MEDICAL SYSTEMS, INC.
    Inventors: John R. Adler, JR., David H. Whittum, Steven W. Prince, James E. Clayton
  • Patent number: 8337382
    Abstract: Radiosurgical techniques and systems treat behavioral disorders (such as depression, Obsessive-Compulsive Disorder (“OCD”), addiction, hyperphagia, and the like) by directing radiation from outside the patient toward a target tissue within the patient's brain, typically without imposing surgical trauma. The target will often be included in a neural circuit associated with the behavioral disorder. A cellularly sub-lethal dose of the radiation may be applied and the radiation can mitigate the behavioral disorder, obesity, or the like, by modulating the level of neural activity within the target and in associated tissues. Hypersensitive and/or hyperactive neuronal tissue may be targeted, with the radiation downwardly modulating hyperactive neuronal activity. By down-regulating the activity of a target that normally exerts negative feedback or a limiting effect on a relevant neural circuit, the activity of the circuit may be increased.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: December 25, 2012
    Inventors: M. Bret Schneider, John R. Adler, Jr., Doyle John Borchers, III, Michele Borchers, legal representative
  • Publication number: 20090114849
    Abstract: Radiosurgical techniques and systems treat behavioral disorders (such as depression, Obsessive-Compulsive Disorder (“OCD”), addiction, hyperphagia, and the like) by directing radiation from outside the patient toward a target tissue within the patient's brain, typically without imposing surgical trauma. The target will often be included in a neural circuit associated with the behavioral disorder. A cellularly sub-lethal dose of the radiation may be applied and the radiation can mitigate the behavioral disorder, obesity, or the like, by modulating the level of neural activity within the target and in associated tissues. Hypersensitive and/or hyperactive neuronal tissue may be targeted, with the radiation downwardly modulating hyperactive neuronal activity. By down-regulating the activity of a target that normally exerts negative feedback or a limiting effect on a relevant neural circuit, the activity of the circuit may be increased.
    Type: Application
    Filed: October 30, 2008
    Publication date: May 7, 2009
    Inventors: M. Bret Schneider, John R. Adler, JR., Doyle John Borchers, Michele Borchers
  • Patent number: 5485085
    Abstract: Disclosed is a method to correct the geometric distortion caused by field inhomogeneity in MR images such as images of patients wearing MR-compatible stereotaxic frames. A previous distortion correction method derives patient-dependent error maps by computing the phase-difference of 3D images acquired at different T.sub.E 's. The time difference (.DELTA.T.sub.E =4.9 ms at 1.5 T) is chosen such that the water and fat signals are in phase. However, .DELTA.T.sub.E is long enough to permit phase wraps in the difference images for frequency offsets greater than 205 Hz. Phase unwrapping techniques resolve these only for connected structures; therefore the phase difference for fiducial rods may be off by multiples of 2 .pi. relative to the head. This uncertainty is removed by using an additional single 2D phase-difference image with .DELTA.T.sub.E =1 ms (during which time no phase-wraps are typically expected) to determine the correct multiple of 2 .pi. for each rod.
    Type: Grant
    Filed: November 28, 1994
    Date of Patent: January 16, 1996
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventors: Thilaka Sumanaweera, Sandy A. Napel, Gary H. Glover, John R. Adler, Jr.