Patents by Inventor John R. Androsavich

John R. Androsavich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20240141350
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: November 30, 2023
    Publication date: May 2, 2024
    Applicants: Regulus Therapeutics Inc., The Board of Regents of The University of Texas System
    Inventors: Charles R. ALLERSON, Vishal D. PATEL, B. Nelson CHAU, John R. ANDROSAVICH
  • METHODS AND COMPOSITIONS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20220380767
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: July 22, 2022
    Publication date: December 1, 2022
    Applicants: Regulus Therapeutics Inc., The Board of Regents of The University of Texas System
    Inventors: Charles R. ALLERSON, Vishal D. PATEL, B. Nelson CHAU, John R. ANDROSAVICH
  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20220213483
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Applicants: Regulus Therapeutics Inc., The Board of Regents of The University of Texas System
    Inventors: Charles R. ALLERSON, Vishal D. PATEL, B. Nelson CHAU, John R. ANDROSAVICH
  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20220025372
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: October 5, 2021
    Publication date: January 27, 2022
    Applicants: Regulus Therapeutics Inc., Board of Regents of The University of Texas System
    Inventors: John R. ANDROSAVICH, B. Nelson CHAU, Vishal D. PATEL
  • MESSENGER RNA THERAPY FOR TREATMENT OF OCULAR DISEASES
    Publication number: 20220016265
    Abstract: The present invention provides, among other things, a method of ocular delivery of messenger RNA (mRNA), comprising administering into an eye of a subject in need of delivery a composition comprising an mRNA encoding a protein, such that the administration of the composition results in expression of the protein encoded by the mRNA in the eye.
    Type: Application
    Filed: November 8, 2019
    Publication date: January 20, 2022
    Inventors: John R. Androsavich, Frank DeRosa, Shrirang Karve
  • Methods for treatment of polycystic kidney disease
    Patent number: 11168325
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: November 9, 2021
    Assignees: Regulus Therapeutics Inc., Board of Regents of The University of Texas System
    Inventors: John R. Androsavich, B. Nelson Chau, Vishal D. Patel
  • METHODS AND COMPOSITIONS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20200392503
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 17, 2020
    Applicants: Regulus Therapeutics Inc., The Board of Regents of the University of Texas System
    Inventors: Charles R. ALLERSON, Vishal D. PATEL, B. Nelson CHAU, John R. ANDROSAVICH
  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20200392501
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: August 27, 2020
    Publication date: December 17, 2020
    Applicants: Regulus Therapeutics Inc., The Board of Regents of the University of Texas System
    Inventors: Charles R. ALLERSON, Vishal D. PATEL, B. Nelson CHAU, John R. ANDROSAVICH
  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20200231971
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: March 19, 2020
    Publication date: July 23, 2020
    Applicants: Regulus Therapeutics Inc., Board of Regents of the University of Texas System
    Inventors: John R. ANDROSAVICH, B. Nelson CHAU, Vishal D. PATEL
  • Methods for treatment of polycystic kidney disease
    Patent number: 10633657
    Abstract: Provided herein are methods for the treatment of poly-cystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: April 28, 2020
    Assignees: Regulus Therapeutics Inc., Board of Regents of the University of Texas System
    Inventors: John R. Androsavich, B. Nelson Chau, Vishal D. Patel
  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20190345494
    Abstract: Provided herein are methods for the treatment of polycystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: December 4, 2017
    Publication date: November 14, 2019
    Inventors: Charles R. ALLERSON, Vishal D. PATEL, B. Nelson CHAU, John R. ANDROSAVICH
  • METHODS FOR TREATMENT OF POLYCYSTIC KIDNEY DISEASE
    Publication number: 20190153442
    Abstract: Provided herein are methods for the treatment of poly-cystic kidney disease, including autosomal dominant polycystic kidney disease, using modified oligonucleotides targeted to miR-17.
    Type: Application
    Filed: August 25, 2016
    Publication date: May 23, 2019
    Applicants: Regulus Therapeutics Inc., Board of Regents of the University of Texas System
    Inventors: John R. Androsavich, B. Nelson Chau, Vishal D. Patel
  • METHODS FOR DIRECT MEASUREMENT OF MICRORNA INHIBITION AND MIMICRY
    Publication number: 20180363056
    Abstract: The disclosure includes methods of determining the activity of an inhibitor of a target microRNA (miRNA) or of a mimic of a target microRNA. Determination of polysome occupancy in treated and control samples followed by comparing the occupancies can be used to determine a displacement value for the inhibitor or mimic of the target miRNA. The displacement value reflects the extent of a change in the levels of the target miRNA (which may include the mimic if applicable) in polysomal and non-polysomal compartments of a sample or a shift of the target miRNA between polysomal and non-polysomal compartments of a sample and can indicate the activity of the inhibitor toward the target miRNA or of the mimic toward a target RNA.
    Type: Application
    Filed: September 2, 2016
    Publication date: December 20, 2018
    Applicant: Regulus Therapeutics Inc.
    Inventors: John R. Androsavich, B. Nelson Chau, Ryan R. Galasso