Patents by Inventor John R. Bend

John R. Bend has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of optically pure thromboxanes
    Patent number: 4256646
    Abstract: In an elegant stepwise process for the production of intermediates of thromboxanes such as TXB.sub.2 from a chiral glucose starting material such as .alpha.-methylglucoside, those steps comprising: ##STR1## A key modification introduced in this synthetic sequence is the use of 4-dimethylaminopyridine for the selective alkylation of primary alcohols in the presence of unprotected secondary alcohols and for the controlled acylation of methylglucoside. The former application has large potential use in the synthesis of nucleosides, polynucleotides, and carbohydrate derivatives.
    Type: Grant
    Filed: April 16, 1979
    Date of Patent: March 17, 1981
    Assignee: The United States of America as represented by the Department of Health, Education and Welfare
    Inventors: Oscar Hernandez, John R. Bend, Thomas E. Eling, James D. McKinney