Abstract: A retaining device for retaining a shower caddy or other item on a shower arm or other elongated member includes a clip structure for partially surrounding the shower arm or elongated member and having retaining arms extending therefrom and a plastic sleeve structure having receptacles for receiving the retaining arms to hold the sleeve structure on the clip structure, and a shower-arm engaging portion or elongated member engaging portion for engaging the shower arm or elongated member to render the shower caddy or other item immobile on the shower arm or elongated member.

Abstract: A tension rod comprising in its preferred form an outer tube and an inner tube in a telescoping arrangement. The outer tube has an expansion joint structure which can engage the inner surface of the outer tube to hold it in place. A spring stem-wedge-rod structure has a wedge portion with a threaded rod extending therefrom for being threaded through a nut held in the expansion rod structure. The spring stem-wedge-rod structure has a stem extending through a coil spring, and a spring retainer is fixed both to the stem and to the inner tube. Twisting of the inner tube causes the wedge portion to effect the expansion joint structure to be fixed in the outer tube, and the coil spring provides the tension to mount the tension rod between a pair of opposing wall surfaces.

Abstract: A tension rod comprising in its preferred form an outer tube and an inner tube in a telescoping arrangement. The outer tube has an expansion joint structure which can engage the inner surface of the outer tube to hold it in place. A spring stem-wedge-rod structure has a wedge portion with a threaded rod extending therefrom for being threaded through a nut held in the expansion rod structure. The spring stem-wedge-rod structure has a stem extending through a coil spring, and a spring retainer is fixed both to the stem and to the inner tube. Twisting of the inner tube causes the wedge portion to effect the expansion joint structure to be fixed in the outer tube, and the coil spring provides the tension to mount the tension rod between a pair of opposing wall surfaces.

Abstract: A retaining device for retaining a shower caddy or other item on a shower arm or other elongated member includes a clip structure for partially surrounding the shower arm or elongated member and having retaining arms extending therefrom and a plastic sleeve structure having receptacles for receiving the retaining arms to hold the sleeve structure on the clip structure, and a shower-arm engaging portion or elongated member engaging portion for engaging the shower arm or elgongated member to render the shower caddy or other item immobile on the shower arm or elongated member.

Abstract: The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products.

Abstract: Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.

Abstract: The invention provides novel compounds that may be used as intermediates in the preparation of epothilones, epothilone analogs and derivative, as well as new synthetic methods for producing the intermediates and products.

Abstract: Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the biosynthesis of the natural starter unit 3-amino-5-hydroxybenzoic acid has been deleted.

Abstract: Migrastatin and a migrastatin analog can be produced by fermentation of Streptomyces platensis NRRL 18993 and used in pharmaceutical formulations to treat cancer and/or inhibit metastasis of cancer cells.

Abstract: This invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, W, X, Y, and Ar are as defined herein. Compounds of formula (I) are useful in the treatment of diseases or conditions characterized by cellular hyperproliferation. This invention also relates to means for the preparation of compounds of formula (I); formulations containing compounds of formula (I); and methods for the use of said compounds and formulations in the treatment of a disease or condition characterized by cellular hyperproliferation, including cancer.

Abstract: This present invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, R3, R4, R5, W, X, Y, and Ar are as defined herein. Compounds of formula (I) are useful in the treatment of diseases or conditions characterized by cellular hyperproliferation. This invention also relates to means for the preparation of compounds of formula (I); formulations containing compounds of formula (I); and methods for the use of said compounds and formulations in the treatment of a disease or condition characterized by cellular hyperproliferation, including cancer.

Abstract: The present invention relates to compounds of the formula: 1