Patents by Inventor John R. E. Hoover

John R. E. Hoover has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-Hydroxyhalophenylacetamido-3-heterocyclicthiomethyl cephalosporins
    Patent number: 4133882
    Abstract: Cephalosporin compounds substituted in the 7-position with a hydroxy-halo substituted .alpha.-aminophenylacetamido group and in the 3-position with a heterocyclicthiomethyl group are prepared by 7-acylation. The products are antibacterial agents.
    Type: Grant
    Filed: June 28, 1976
    Date of Patent: January 9, 1979
    Assignee: SmithKline Corporation
    Inventors: George L. Dunn, John R. E. Hoover
  • Mercaptopseudotrisaccharides
    Patent number: 4048430
    Abstract: Novel pseudodisaccharide compounds which are related to neamine are prepared. These compounds have a mercapto group or a derivative thereof at position 3 or 4 of the glucose moiety of neamine. The compounds have antibacterial activity and have utility as intermediates to pseudotrisaccharides.
    Type: Grant
    Filed: December 18, 1975
    Date of Patent: September 13, 1977
    Assignee: SmithKline Corporation
    Inventors: David J. Cooper, John R. E. Hoover, Jerry A. Weisbach
  • P-Hydroxymethylphenylacetamidocephalosporins
    Patent number: 3987041
    Abstract: 7-(p-Hydroxymethylphenylglycylamido)cephalosporins are prepared by acylating a 7-aminocephalosporin compound. The products have antibacterial activity.
    Type: Grant
    Filed: February 25, 1975
    Date of Patent: October 19, 1976
    Assignee: SmithKline Corporation
    Inventors: George L. Dunn, John R. E. Hoover
  • 3-Heterocyclic thiomethylcephalosporins
    Patent number: 3985739
    Abstract: Cephalosporin compounds substituted at the 7-position with free or substituted .alpha.-amino or hydroxy phenylacetamido and at the 3-position with a heterocyclic thiomethyl group are prepared by displacement of a 3-acetoxymethyl compound with a mercaptoheterocycle or by 7-acylation. The products are antibacterial agents.
    Type: Grant
    Filed: October 1, 1974
    Date of Patent: October 12, 1976
    Assignee: SmithKline Corporation
    Inventors: George L. Dunn, John R. E. Hoover
  • Cephalosporin intermediates and process therefor
    Patent number: 3976641
    Abstract: Novel 7-oxocephalosporins and a process for preparing them are disclosed. These compounds are useful intermediates in the preparation of other cephalosporins which have antibacterial activity.
    Type: Grant
    Filed: November 14, 1974
    Date of Patent: August 24, 1976
    Assignee: SmithKline Corporation
    Inventors: John R. E. Hoover, Timothy Yu-Wen Jen
  • p-Hydroxymethylphenylglycine
    Patent number: 3972919
    Abstract: 7-(p-Hydroxymethylphenylglycylamido)cephalosporins are prepared by acylating a 7-aminocephalosporin compound. The products have antibacterial activity.
    Type: Grant
    Filed: February 25, 1975
    Date of Patent: August 3, 1976
    Assignee: SmithKline Corporation
    Inventors: George L. Dunn, John R. E. Hoover
  • 3-Heterocyclic thiomethylcephalosporins as antibacterial agents
    Patent number: 3968226
    Abstract: Cephalosporin compounds substituted at the 7-position with free or substituted .alpha.-aminophenylacetamido and at the 3-position with a heterocyclic thiomethyl group are prepared by displacement of a 3-acetoxymethyl compound with a mercaptoheterocycle. The products are antibacterial agents.
    Type: Grant
    Filed: September 30, 1974
    Date of Patent: July 6, 1976
    Assignee: SmithKline Corporation
    Inventors: George L. Dunn, John R. E. Hoover
  • Cephalosporin esters with antibacterial activity
    Patent number: 3965099
    Abstract: Esters of 7-trifluoromethylmercaptoacetamido-3-(1-methyltetrazol-5-ylthiomethyl)-3-c ephem-4-carboxylic acid are prepared. These compounds are antibacterial agents.
    Type: Grant
    Filed: June 26, 1974
    Date of Patent: June 22, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. DeMarinis, John R. E. Hoover
  • P-hydroxymethylphenylacetamidocephalosporins
    Patent number: 3962230
    Abstract: 7-(p-Hydroxymethylphenylglycylamido)cephalosporins are prepared by acylating a 7-aminocephalosporin compound. The products have antibacterial activity.
    Type: Grant
    Filed: February 25, 1975
    Date of Patent: June 8, 1976
    Assignee: SmithKline & French Laboratories, Inc.
    Inventors: George L. Dunn, John R. E. Hoover
  • Substituted sulfonylacetamido cephalosporins
    Patent number: 3960852
    Abstract: Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: June 1, 1976
    Inventors: Robert M. De Marinis, John R. E. Hoover
  • Substituted sulfonylacetamido cephalosporins
    Patent number: 3960853
    Abstract: Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: June 1, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. De Marinis, John R. E. Hoover
  • Mercaptopseudodisaccharides
    Patent number: 3960838
    Abstract: Novel pseudodisaccharide compounds which are related to neamine are prepared. These compounds have a mercapto group or a derivative thereof at position 3 or 4 of the glucose moiety of neamine. The compounds have antibacterial activity and have utility as intermediates to pseudotrisaccharides.
    Type: Grant
    Filed: October 29, 1974
    Date of Patent: June 1, 1976
    Assignee: SmithKline Corporation
    Inventors: David J. Cooper, John R. E. Hoover, Jerry A. Weisbach
  • Substituted sulfonylacetamido cephalosporins
    Patent number: 3960855
    Abstract: Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: June 1, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. De Marinis, John R. E. Hoover
  • Substituted sulfonylacetamido cephalosporins
    Patent number: 3948905
    Abstract: Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: April 6, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. De Marinis, John R. E. Hoover
  • Trifluoromethylmercaptoacetamidocephalosporins
    Patent number: 3943131
    Abstract: This invention is directed to antibacterial compounds, in particular, to 7-trifluoromethylmercaptoacetamidocephalosporins.
    Type: Grant
    Filed: April 22, 1974
    Date of Patent: March 9, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. De Marinis, John R. E. Hoover
  • 7-Trifluoromethylsulfinylacetamido cephalosporins
    Patent number: 3943127
    Abstract: Cephalosporin compounds having a trifluoromethylsulfinylacetamido group at the 7-position and various groups at the 3-position are prepared by acylation of a 7-aminocephalosporanic acid. The compounds have antibacterial activity.
    Type: Grant
    Filed: January 20, 1975
    Date of Patent: March 9, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. DeMarinis, John R. E. Hoover
  • 7-Trifluoromethylsulfinylacetamido cephalosporins
    Patent number: 3943128
    Abstract: Cephalosporin compounds having a trifluoromethylsulfinylacetamido group at the 7-position and various groups at the 3-position are prepared by acylation of a 7-aminocephalosporanic acid. The compounds have antibacterial activity.
    Type: Grant
    Filed: January 20, 1975
    Date of Patent: March 9, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. DeMarinis, John R. E. Hoover
  • Substituted sulfonylacetamido cephalosporins
    Patent number: 3939266
    Abstract: Cephalosporin compounds having various substituted sulfonylacetamido groups at position 7 have been prepared and have antibacterial activity.
    Type: Grant
    Filed: December 3, 1974
    Date of Patent: February 17, 1976
    Assignee: SmithKline Corporation
    Inventors: Robert M. De Marinis, John R. E. Hoover