Patents by Inventor John R. Eisenbrey

John R. Eisenbrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-invasive method for pressure measurement
    Patent number: 11317888
    Abstract: The present invention relates to the use of contrast-enhanced ultrasound using microbubble-based ultrasound contrast agents to accomplish noninvasive subharmonic aided pressure estimation (SHAPE) in a region of interest (ROI) of a subject. The method of the invention provides a non-invasive, direct, and accurate method for pressure estimation.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: May 3, 2022
    Assignees: THOMAS JEFFERSON UNIVERSITY, GE PRECISION HEALTHCARE LLC
    Inventors: Flemming Forsberg, David Mills, John R. Eisenbrey, Kirk Wallace, Ipshita Gupta
  • NON-INVASIVE METHOD FOR PRESSURE MEASUREMENT
    Publication number: 20200046313
    Abstract: The present invention relates to the use of contrast-enhanced ultrasound using microbubble-based ultrasound contrast agents to accomplish noninvasive subharmonic aided pressure estimation (SHAPE) in a region of interest (ROI) of a subject. The method of the invention provides a non-invasive, direct, and accurate method for pressure estimation.
    Type: Application
    Filed: October 11, 2017
    Publication date: February 13, 2020
    Applicants: THOMAS JEFFERSON UNIVERSITY, GE HEALTHCARE LIMITED
    Inventors: Flemming Forsberg, David Mills, John R. Eisenbrey, Kirk Wallace, Ipshita Gupta
  • Antibiotic drug release sheath
    Patent number: 10485902
    Abstract: An implantable medical device having a sheath formed of a polymer material, wherein the sheath forms a reservoir attached to or around the implantable medical device, and wherein the reservoir is sealed with a biocompatible pressure responsive coating; wherein the biocompatible coating is stable for at least 7-day post implantation into a body, and can be mechanically ruptured by application of an exterior pressure generating force.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: November 26, 2019
    Assignees: Thomas Jefferson University, Drexel University
    Inventors: Christopher K. Kepler, Alex Michael Sevit, Steven Michael Kurtz, Noreen J. Hickok, Flemming Forsberg, John R. Eisenbrey
  • ANTIBIOTIC DRUG RELEASE SHEATH
    Publication number: 20170056565
    Abstract: An implantable medical device having a sheath formed of a polymer material, wherein the sheath forms a reservoir attached to or around the implantable medical device, and wherein the reservoir is sealed with a biocompatible pressure responsive coating; wherein the biocompatible coating is stable for at least 7-day post implantation into a body, and can be mechanically ruptured by application of an exterior pressure generating force.
    Type: Application
    Filed: August 29, 2016
    Publication date: March 2, 2017
    Applicants: Thomas Jefferson University, Drexel University
    Inventors: Christopher K. Kepler, Alex Michael Sevit, Steven Michael Kurtz, Noreen J. Hickok, Flemming Forsberg, John R. Eisenbrey
  • Drug loaded contrast agents: combining diagnosis and therapy
    Patent number: 9220709
    Abstract: This invention provides an improvement to methods of drug loading of ultrasound contrast agents. Echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof produced by the method of the invention wherein the echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof contain at least 10% more of a drug as compared to (1) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug prior to emulsifying or (2) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug to lyophilized polymer microcapsules, nanocapsules, or mixtures thereof.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: December 29, 2015
    Assignee: Drexel University
    Inventors: Margaret A. Wheatley, Odelia Mualem Burstein, John R. Eisenbrey, Dalia El-Sherif
  • Drug Loaded Contrast Agents: Combining Diagnosis and Therapy
    Publication number: 20090196827
    Abstract: This invention provides an improvement to methods of drug loading of ultrasound contrast agents. Echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof produced by the method of the invention wherein the echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof contain at least 10% more of a drug as compared to (1) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug prior to emulsifying or (2) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug to lyophilized polymer microcapsules, nanocapsules, or mixtures thereof.
    Type: Application
    Filed: May 21, 2007
    Publication date: August 6, 2009
    Applicant: Drexel University
    Inventors: Margaret A. Wheatley, Odelia Mualem Burstein, John R. Eisenbrey, Dalia El-Sherif