Abstract: A gas turbine engine includes a fan and an engine core configured to provide rotational power during operation of the gas turbine engine. The engine core includes a compressor, a combustor, and a turbine. An oil sump is located in the engine core and is configured to collect oil from the engine core. The gas turbine engine further includes a gearbox configured to be driven by the engine core during operation of the gas turbine engine and an oil pump assembly configured to move the oil from the oil sump to an oil tank and/or to the engine core.

Abstract: An air-oil separation system for a gas turbine engine system comprises a housing that extends circumferentially around an axis to define an interior chamber of the housing and a separation unit located in the chamber. The housing is formed to include an inlet configured to receive a mixture of air and oil, an oil outlet configured to conduct oil to exit the housing, and an air outlet configured to conduct air to exit the housing. The air-oil separation unit separates air from the oil.

Abstract: A gas turbine engine includes a power unit and an oil system configured to lubricate the power unit during operation of the gas turbine engine. The power unit includes an engine core and a fan coupled with the engine core and driven by the engine core to produce thrust for propelling the gas turbine engine during operation of the gas turbine engine.

Abstract: A gearbox is provided for use in a gas turbine engine. The gearbox includes a plurality of gears, a casing surrounding the plurality of gears, and a lubricant re-circulation system. The casing defines a sump positioned beneath the plurality of gears to retain lubricant. The lubricant re-circulation system includes a re-circulation pump, a re-circulation inlet positioned within the sump, and a re-circulation outlet positioned to supply lubricant to the plurality of gears.

Abstract: A gas turbine engine includes a first spool and a second spool. The first spool includes a compressor stage, a first turbine stage, and a first shaft configured to transmit rotational energy between the first turbine stage and the compressor stage. The second spool includes a fan, a second turbine stage, and a second shaft configured to transmit rotational energy between the second turbine stage and the fan.

Abstract: A gas turbine engine includes an engine core, a power gearbox, and a lubrication system. The engine core is configured to drive rotation of at least one shaft. The power gearbox is configured to transfer torque from the at least one shaft to other parts of the gas turbine engine. The lubrication system is configured to deliver lubrication to the power gearbox to reduce friction and cool rotating components within the power gearbox.

Abstract: A gas turbine engine includes a first spool and a second spool. The first spool includes a compressor stage, a first turbine stage, and a first shaft configured to transmit rotational energy between the first turbine stage and the compressor stage. The second spool includes a fan, a second turbine stage, and a second shaft configured to transmit rotational energy between the second turbine stage and the fan.

Abstract: A gas turbine engine includes an engine core, a power gearbox, and a lubrication system. The engine core is configured to drive rotation of at least one shaft. The power gearbox is configured to transfer torque from the at least one shaft to other parts of the gas turbine engine. The lubrication system is configured to deliver lubrication to the power gearbox to reduce friction and cool rotating components within the power gearbox.

Abstract: An air-oil separation system for a gas turbine engine system comprises a housing that extends circumferentially around an axis to define an interior chamber of the housing and a separation unit located in the chamber. The housing is formed to include an inlet configured to receive a mixture of air and oil, an oil outlet configured to conduct oil to exit the housing, and an air outlet configured to conduct air to exit the housing. The air-oil separation unit separates air from the oil.

Abstract: A gearbox is provided for use in a gas turbine engine. The gearbox includes a plurality of gears, a casing surrounding the plurality of gears, and a lubricant re-circulation system. The casing defines a sump positioned beneath the plurality of gears to retain lubricant. The lubricant re-circulation system includes a re-circulation pump, a re-circulation inlet positioned within the sump, and a re-circulation outlet positioned to supply lubricant to the plurality of gears.

Abstract: A gas turbine engine includes a power unit and an oil system configured to lubricate the power unit during operation of the gas turbine engine. The power unit includes an engine core and a fan coupled with the engine core and driven by the engine core to produce thrust for propelling the gas turbine engine during operation of the gas turbine engine.

Abstract: A gas turbine engine includes a fan and an engine core configured to provide rotational power during operation of the gas turbine engine. The engine core includes a compressor, a combustor, and a turbine. An oil sump is located in the engine core and is configured to collect oil from the engine core. The gas turbine engine further includes a gearbox configured to be driven by the engine core during operation of the gas turbine engine and an oil pump assembly configured to move the oil from the oil sump to an oil tank and/or to the engine core.

Abstract: The present invention is directed to methods of treating eye disease. In one embodiment, the method can comprise administering a bioconjugate to a subject to treat the eye disease, where the bioconjugate comprises a taxane covalently bonded to a cobalamin. Additionally, the bioconjugate can be dissolved in an aqueous solution prior to administration.

Abstract: The present invention is directed to methods and compositions including a taxane covalently bonded to the cobalt atom of a cobalamin. The composition can be delivered by any effective route, but is particularly useful as an oral anti-cancer or antiangiogenic compound. The anti-cancer/anti-angiogenic compound can be used in various chemotherapies including anti-angiogenic chemotherapies, alone or in combination with other anti-cancer/anti-angiogenic compounds.

Abstract: The present invention is directed to methods of treating eye disease. In one embodiment, the method can comprise administering a taxane-cobalamin bioconjugate or another taxane compound to a subject to treat the eye disease. In one embodiment, the bioconjugate can be dissolved in an aqueous solution prior to administration.

Abstract: The present invention is directed to methods of treating eye disease. In one embodiment, the method can comprise administering a taxane-cobalamin bioconjugate or another taxane compound to a subject to treat the eye disease. In one embodiment, the bioconjugate can be dissolved in an aqueous solution prior to administration.

Abstract: The present invention is directed to methods and compositions including a taxane covalently bonded to the cobalt atom of a cobalamin. The composition can be delivered by any effective route, but is particularly useful as an oral anti-cancer or antiangiogenic compound. The anti-cancer/anti-angiogenic compound can be used in various chemotherapies including anti-angiogenic chemotherapies, alone or in combination with other anti-cancer/anti-angiogenic compounds.

Abstract: The present invention is related to acute therapeutic uses of dehydroepiandrosterone (DHEA) congeners. These uses include methods for treating or preventing ulcers which comprise administering to a subject either at risk or in need thereof having an ulcer a therapeutic amount of DHEA congener.