Patents by Inventor John R. Hess
John R. Hess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9314014Abstract: The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one non-metabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.Type: GrantFiled: February 17, 2005Date of Patent: April 19, 2016Assignees: University of Maryland, Baltimore, University of CincinnatiInventors: John R. Hess, Tibor J. Greenwalt
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Publication number: 20140342347Abstract: The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.Type: ApplicationFiled: April 18, 2014Publication date: November 20, 2014Inventors: John R. Hess, Tibor J. Greenwalt
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Patent number: 8709707Abstract: The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.Type: GrantFiled: September 10, 2012Date of Patent: April 29, 2014Inventors: John R. Hess, Tibor J. Greenwalt
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Publication number: 20120329036Abstract: The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.Type: ApplicationFiled: September 10, 2012Publication date: December 27, 2012Inventors: John R. Hess, Tibor J. Greenwalt
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Publication number: 20120129148Abstract: The present invention provides an aqueous composition for storage of red blood cells consisting essentially of: adenine; dextrose; at least one nonmetabolizable membrane-protectant sugar; and a specifically defined pH buffering system. Also provided are improved methods for preserving red blood cells and methods for increasing the viability, membrane retention, and recoverability while suppressing apoptosis, hemolysis, and post-reinfusion clearance of stored red blood cells which utilize the novel compositions.Type: ApplicationFiled: January 20, 2012Publication date: May 24, 2012Inventors: John R. Hess, Tibor J. Greenwalt
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Publication number: 20100222120Abstract: A particulate residue separator and a method for separating a particulate residue stream may include a plenum borne by a harvesting device, and have a first, intake end and a second, exhaust end; first and second particulate residue air streams which are formed by the harvesting device and which travel, at least in part, along the plenum and in a direction of the second, exhaust end; and a baffle assembly which is located in partially occluding relation relative to the plenum, and which substantially separates the first and second particulate residue air streams.Type: ApplicationFiled: May 11, 2010Publication date: September 2, 2010Applicant: BATTELLE ENERGY ALLIANCE, LLCInventors: Reed L. Hoskinson, Kevin L. Kenney, Christopher T. Wright, John R. Hess
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Patent number: 7744450Abstract: A particulate residue separator and a method for separating a particulate residue stream may include a plenum borne by a harvesting device, and have a first, intake end and a second, exhaust end; first and second particulate residue air streams which are formed by the harvesting device and which travel, at least in part, along the plenum and in a direction of the second, exhaust end; and a baffle assembly which is located in partially occluding relation relative to the plenum, and which substantially separates the first and second particulate residue air streams.Type: GrantFiled: September 28, 2006Date of Patent: June 29, 2010Assignee: Battelle Energy Alliance, LLCInventors: Reed L. Hoskinson, Kevin L. Kenney, Christopher T. Wright, John R. Hess
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Publication number: 20080081680Abstract: A particulate residue separator and a method for separating a particulate residue stream is shown and described and which includes a plenum borne by a harvesting device, and having a first, intake end, and a second, exhaust end; first and second particulate residue air streams which are formed by the harvesting device and which travel, at least in part, along the plenum and in the direction of the second end; and a baffle assembly which is located in partially occluding relation relative to the plenum, and which substantially separates the particulate residue air streams.Type: ApplicationFiled: September 28, 2006Publication date: April 3, 2008Inventors: Reed L. Hoskinson, Kevin L. Kenney, Christopher T. Wright, John R. Hess
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Patent number: 6825323Abstract: The combination of recombinant factor VIIa and fibrinogen is effective in treatment for bleeding where direct pressure, tourniquets, indirect pressure, surgical ligation, bandaging, and transfusion of blood or plasma products are typically used. The combination of factor VIIa and fibrinogen is administered intravenously, either sequentially or simultaneously. The compositions may be safely circulated in the blood vessels to sites of injury. This is effective for single or multiple external or internal wounds.Type: GrantFiled: January 10, 2001Date of Patent: November 30, 2004Assignee: The United States of America as represented by the Secretary of the ArmyInventor: John R. Hess
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Publication number: 20040198647Abstract: The combination of recombinant factor VIIa and fibrinogen is effective in treatment for bleeding where direct pressure, tourniquets, indirect pressure, surgical ligation, bandaging, and transfusion of blood or plasma products are typically used. The combination of factor VIIa and fibrinogen is administered intravenously, either sequentially or simultaneously. The compositions may be safely circulated in the blood vessels to sites of injury. This is effective for single or multiple external or internal wounds.Type: ApplicationFiled: January 10, 2001Publication date: October 7, 2004Inventor: John R. Hess
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Patent number: 6497153Abstract: The present invention provides systems and methods for measuring a load force associated with pulling a farm implement through soil that is used to generate a spatially variable map that represents the spatial variability of the physical characteristics of the soil. An instrumented hitch pin configured to measure a load force is provided that measures the load force generated by a farm implement when the farm implement is connected with a tractor and pulled through or across soil. Each time a load force is measured, a global positioning system identifies the location of the measurement. This data is stored and analyzed to generate a spatially variable map of the soil. This map is representative of the physical characteristics of the soil, which are inferred from the magnitude of the load force.Type: GrantFiled: September 28, 2000Date of Patent: December 24, 2002Assignee: Bechtel BWXT Idaho, LLCInventors: Reed L. Hoskinson, John M. Svoboda, J. Wayne Sawyer, John R. Hess, J. Richard Hess
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Patent number: 6447987Abstract: Novel additive solutions useful for the storage of human red blood cells (RBCs) under refrigerated conditions are disclosed. Also disclosed is a method of using the additive solutions in an appropriate volume to preserve RBCs at about 1 to 6° C. for up to at least about 11 weeks or more. Additive solutions and processes in accordance with the present invention allow the viable storage of human RBCs for an extended period of time in a solution which is directly infusible in humans.Type: GrantFiled: September 19, 2000Date of Patent: September 10, 2002Assignee: The United States of America as represented by the Secretary of the ArmyInventors: John R. Hess, Tibor J. Greenwalt
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Patent number: 6150085Abstract: Novel additive solutions useful for the storage of human red blood cells (RBCs) under refrigerated conditions are disclosed. Also disclosed is a method of using the additive solutions in an appropriate volume to preserve RBCs at about 1 to 6.degree. C. for up to 10 weeks. Additive solutions and processes in accordance with the present invention allow the viable storage of human RBCs for an extended period of time in a solution which is directly infusible in humans.Type: GrantFiled: September 16, 1998Date of Patent: November 21, 2000Assignee: The United States of America as represented by the Secretary of the ArmyInventors: John R. Hess, Tibor J. Greenwalt
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Patent number: 5605438Abstract: A turbine casing is provided in two casing halves joined one to the other along a horizontal splitline having flanges with spaced boltholes. A circumferentially extending rib is provided about each casing half at a location just forward of the turbine buckets to minimize or eliminate distortion caused by internal pressure and meridional roll of the casing. One or more axially extending ribs is provided on each casing half. The axial ribs have a radial stiffness which substantially matches the stiffness and thermal response of the flanges.Type: GrantFiled: December 29, 1995Date of Patent: February 25, 1997Assignee: General Electric Co.Inventors: Steven S. Burdgick, John R. Hess, Gary D. Mercer, Gregory A. Crum, James E. Cencula, John A. Eastman
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Patent number: 5174714Abstract: A heat shield mechanism for shielding a structure in a turbine engine having a sheet metal backing which is bonded to a plurality of honeycomb cells aligned in a radially outward manner toward a casing. The honeycomb cells and sheet metal backing form a heat shield which acts as a vortex destroyer by eliminating fluid flow around the turbine structure.Type: GrantFiled: July 9, 1991Date of Patent: December 29, 1992Assignee: General Electric CompanyInventors: Larry W. Plemmons, John R. Hess
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Patent number: 5169287Abstract: To cool the shroud in the high pressure turbine section of a gas turbine engine, high pressure cooling air is directed in metered flow to baffle plenums and thence through baffle perforations to impingement cool the shroud rails and back surface. Impingement cooling air then flows through elongated, convection cooling passages in the shroud and exits to flow along the shroud front surface with the main gas stream to provide film cooling. The baffle perforations and the convection cooling passages are interactively located to achieve maximum cooling benefit and highly efficient cooling air utilization.Type: GrantFiled: May 20, 1991Date of Patent: December 8, 1992Assignee: General Electric CompanyInventors: Robert Proctor, Larry W. Plemmons, Gulcharan S. Brainch, John R. Hess, Robert J. Albers
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Patent number: 5165847Abstract: To cool the shroud in the high pressure turbine section of a gas turbine engine, high pressure cooling air is directed in metered flow through channels, which include tapered enlargement frustroconical recuperators, to baffle plenums and thence through baffle perforations to impingement cool the shroud rails and back surface. The baffle perforations and the convection cooling passages are interactively located to achieve maximum cooling benefit and highly efficient cooling air utilization.Type: GrantFiled: May 20, 1991Date of Patent: November 24, 1992Assignee: General Electric CompanyInventors: Robert Proctor, John R. Hess
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Patent number: 5118120Abstract: An apparatus for effecting a seal between two structural components of a turbo machine or similar device comprises a leaf seal located in the space between the two components and a spring which continuously biases the leaf seal into a sealing position against the components regardless of the pressure differential across the leaf seal.Type: GrantFiled: December 27, 1990Date of Patent: June 2, 1992Assignee: General Electric CompanyInventors: Vincent M. Drerup, John R. Hess, Larry W. Plemmons
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Patent number: 5090865Abstract: A windage shield for use with a pair of annular members oriented in an abutting end-to-end arrangement to define one boundary of a fluid flow path, each of the members having a radially extending flange at their respecting abutting ends for coupling the members to each other. The flanges are coupled by a plurality of circumferentially spaced bolts having a head and a nut which protrude into the fluid flow path. The windage shield comprises an annular ring having a first surface with a plurality of circumferentially spaced arcuate grooves formed therein. Each of the grooves is shaped to receive a preselected number of the bolt heads when the ring is positioned against a corresponding flange. A second surface of the ring opposite the first surface includes a plurality of apertures extending through the ring to the first surface with each of the apertures being located between a respective adjacent pair of the arcuate grooves. Each aperture has a countersunk portion on the second surface.Type: GrantFiled: October 22, 1990Date of Patent: February 25, 1992Assignee: General Electric CompanyInventors: Jairaj Ramachandran, John R. Hess, Larry W. Plemmons
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Patent number: 4101245Abstract: An interblade seal and vibration damper to be positioned in the damper cavity defined between a rotor disc, adjacent blades and adjacent blade platforms so as to seal across an interplatform gap by providing line contact between the damper and the platforms on opposite sides thereof for the full axial dimension of the cavity and with the damper shaped so as to have a low center of gravity for operational stability and which damper also responds to centrifugal force during rotor operation to establish damping friction between said damper and said platforms when the platforms move circumferentially.Type: GrantFiled: December 27, 1976Date of Patent: July 18, 1978Assignee: United Technologies CorporationInventors: John R. Hess, Herbert Frederick Asplund