Patents by Inventor John R. Maddison

John R. Maddison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8749627
    Abstract: A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path while the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: June 10, 2014
    Assignee: Source Bioscience PLC
    Inventors: John R. Maddison, Noah F. Clinch
  • Patent number: 8478073
    Abstract: A method for determining a position of an area of an object within the complete object, wherein the image of the area of the object is contained within a field of view of a microscope. The method comprises acquiring high magnification image data representing an image of the field of view of the microscope, typically from a digital camera attached to the microscope; processing the high magnification image data to reduce the resolution thereof; comparing the processed high magnification image data with portions of the low magnification image data, and determining said position based on the results of said comparison.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: July 2, 2013
    Assignee: Hamamatsu Photonics K.K.
    Inventor: John R. Maddison
  • Publication number: 20120293645
    Abstract: A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.
    Type: Application
    Filed: July 31, 2012
    Publication date: November 22, 2012
    Applicant: SOURCE BIOSCIENCE PLC
    Inventors: John R. Maddison, Noah F. Clinch
  • Patent number: 8253788
    Abstract: A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path while the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: August 28, 2012
    Assignee: Source Bioscience PLC
    Inventors: John R. Maddison, Noah F. Clinch
  • Publication number: 20120120225
    Abstract: A method for determining a position of an area of an object within the complete object, wherein the image of the area of the object is contained within a field of view of a microscope. The method comprises acquiring high magnification image data representing an image of the field of view of the microscope, typically from a digital camera attached to the microscope; processing the high magnification image data to reduce the resolution thereof; comparing the processed high magnification image data with portions of the low magnification image data, and determining said position based on the results of said comparison.
    Type: Application
    Filed: December 21, 2011
    Publication date: May 17, 2012
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventor: John R. Maddison
  • Patent number: 8107770
    Abstract: A microscope system and method is described for determining a position of an area of an object within the complete object, wherein the image of the area of the object is contained within a field of view of a microscope. Image data representing a low magnification image of the complete object is available for use in the method, and may be acquired using a low magnification image data source such as a scanner. The method comprises acquiring high magnification image data representing an image of the field of view of the microscope, typically from a digital camera attached to the microscope; processing the high magnification image data to reduce the resolution thereof; comparing the processed high magnification image data with portions of the low magnification image data, and, determining said position based on the results of said comparison.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: January 31, 2012
    Assignee: Hamamatsu Photonics K.K.
    Inventor: John R. Maddison
  • Patent number: 7602996
    Abstract: A microscope system and method is described for determining a position of an area of an object within the complete object, wherein the image of the area of the object is contained within a field of view of a microscope. Image data representing a low magnification image of the complete object is available for use in the method, and may be acquired using a low magnification image data source such as a scanner. In a preferred embodiment, the method is implemented in the form of a computer program running on a workstation, which displays, on a display screen the field of view image, and the image of the complete object, in which the position of the area of the object in field of view is highlighted.
    Type: Grant
    Filed: February 4, 2004
    Date of Patent: October 13, 2009
    Assignee: Hamamatsu Photonics K.K.
    Inventor: John R. Maddison
  • Publication number: 20080285795
    Abstract: A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.
    Type: Application
    Filed: June 17, 2008
    Publication date: November 20, 2008
    Applicant: MEDICAL SOLUTIONS PLC
    Inventors: John R. Maddison, Noah F. Clinch
  • Patent number: 7388599
    Abstract: A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: June 17, 2008
    Assignee: Medical Solutions PLC
    Inventors: John R Maddison, Noah F Clinch
  • Patent number: 7248282
    Abstract: A microscopy imaging system and method acquires digital images of a microscope specimen using a computer-controlled microscope and digital camera. A specimen on a microscope slide is placed within the microscope. The method comprises the steps of determining whether an area of the specimen contained within a microscope field of view has a thickness, and, if so, capturing digital images of the field of view at a plurality of depths of focus. In a preferred embodiment, the step of determining whether an area of the specimen contained within a microscope field of view has a thickness comprises the steps of: capturing a digital image of the field of view at two or more depths of focus; comparing the captured digital images, and determining that the specimen has a thickness, if the comparing step finds that the images are different. The method may be implemented in the form of a computer program.
    Type: Grant
    Filed: February 12, 2003
    Date of Patent: July 24, 2007
    Assignee: Fairfield Imaging Limited
    Inventor: John R Maddison
  • Patent number: 6847729
    Abstract: A method of telemicroscopy comprises the step of preparing a specimen on a microscopy slide. The slide is placed upon the stage of a microscope equipped with digital imaging apparatus and motorised stage and the specimen imaged to obtain a composite high resolution image of the whole specimen. A relatively low resolution copy of that image is obtained and stored in a datastore. The method further comprises the steps of allowing access to the datastore from a terminal transferring the low resolution image to the terminal and displaying the image upon a monitor selecting by means of the remote terminal, as desired, an area of the low resolution image and transferring corresponding high resolution image data for that area from the datastore to the terminal.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: January 25, 2005
    Assignee: Fairfield Imaging Limited
    Inventors: Noah Clinch, John R. Maddison
  • Publication number: 20040184678
    Abstract: A microscope system and method is described for determining a position of an area of an object within the complete object, wherein the image of the area of the object is contained within a field of view of a microscope. Image data representing a low magnification image of the complete object is available for use in the method, and may be acquired using a low magnification image data source such as a scanner. The method comprises acquiring high magnification image data representing an image of the field of view of the microscope, typically from a digital camera attached to the microscope; processing the high magnification image data to reduce the resolution thereof; comparing the processed high magnification image data with portions of the low magnification image data, and, determining said position based on the results of said comparison.
    Type: Application
    Filed: February 4, 2004
    Publication date: September 23, 2004
    Inventor: John R. Maddison
  • Publication number: 20040119817
    Abstract: A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.
    Type: Application
    Filed: December 18, 2002
    Publication date: June 24, 2004
    Inventors: John R. Maddison, Noah F. Clinch
  • Publication number: 20030214706
    Abstract: A microscopy imaging system and method acquires digital images of a microscope specimen using a computer-controlled microscope and digital camera. A specimen on a microscope slide is placed within the microscope. The method comprises the steps of determining whether an area of the specimen contained within a microscope field of view has a thickness, and, if so, capturing digital images of the field of view at a plurality of depths of focus. In a preferred embodiment, the step of determining whether an area of the specimen contained within a microscope field of view has a thickness comprises the steps of: capturing a digital image of the field of view at two or more depths of focus; comparing the captured digital images, and determining that the specimen has a thickness, if the comparing step finds that the images are different. The method may be implemented in the form of a computer program.
    Type: Application
    Filed: February 12, 2003
    Publication date: November 20, 2003
    Inventor: John R. Maddison
  • Patent number: RE42220
    Abstract: A method of telemicroscopy comprises the step of preparing a specimen on a microscopy slide. The slide is placed upon the stage of a microscope equipped with digital imaging apparatus and motorised stage and the specimen imaged to obtain a composite high resolution image of the whole specimen. A relatively low resolution copy of that image is obtained and stored in a datastore. The method further comprises the steps of allowing access to the datastore from a terminal transferring the low resolution image to the terminal and displaying the image upon a monitor selecting by means of the remote terminal, as desired, an area of the low resolution image and transferring corresponding high resolution image data for that area from the datastore to the terminal.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: March 15, 2011
    Assignee: Hamamatsu Photonics K.K.
    Inventors: Noah Clinch, John R. Maddison