Abstract: The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.

Abstract: The present application describes coffee and tea-baking compounds and method for producing the same.

Abstract: A mounting system is provided for securing a metal support surface to a metal bracket on a railroad car. The invention is improved by a compressible, energy absorbing arrangement secured intermediate the support surface and the bracket for preventing metal to metal contact between the support surface and the bracket and absorbing vibrational energy caused by movement of the railroad car.

Abstract: A mounting system is provided for securing a metal support surface to a metal bracket on a railroad car. The invention is improved by a compressible, energy absorbing arrangement secured intermediate the support surface and the bracket for preventing metal to metal contact between the support surface and the bracket and absorbing vibrational energy caused by movement of the railroad car.

Abstract: A video standards converter (VSC) has a first input module, a second input module, a bus attached to the first and second input modules, a first output module attached to the bus and having a first video standard, and a second output module attached to the bus and having a second video standard. The first and second video standards may be different. The first input module may be adapted to convert an analog video signal to a digital signal. The second input module may be adapted to convert an analog video signal to a digital signal. The VSC may include a picture-in-picture feature for displaying images from two different sources simultaneously. The VSC may be employed in methods for converting a signal from a first video standard to a second video standard.

Abstract: A video standards converter (VSC) has a first input module, a second input module, a bus attached to the first and second input modules, a first output module attached to the bus and having a first video standard, and a second output module attached to the bus and having a second video standard. The first and second video standards may be different. The first input module may be adapted to convert an analog video signal to a digital signal. The second input module may be adapted to convert an analog video signal to a digital signal. The VSC may include a picture-in-picture feature for displaying images from two different sources simultaneously. The VSC may be employed in methods for converting a signal from a first video standard to a second video standard.

Abstract: A spark plug printing machine has two silk screens with different color inks mounted side-by-side and facing down. Spark plug insulators are rotatably mounted in a vertical orientation on a turntable. A print transfer pad located beneath the screens is rotatable from a first position, where it is horizontal and contacts the screens, to a second vertical position. In the second position the pad contacts one of the insulators and is displaced along its length to roll the insulator along the pad through more than 360.degree. so that ink from both screens is transferred to the insulator one after the other.

Abstract: A dry-state iontophoretic drug delivery device (10, 30) is provided. The device has drug and electrolyte reservoirs (15, 16) which are initially in a non-hydrated condition. In one embodiment of the invention, a sealed liquid-containing pouch (21, 22) is provided in each electrode assembly (8, 9). Water or other liquid (20) is released from the pouch (21, 22) by pulling a tab (27, 28) attached to a portion (25, 26) of the pouch (21, 22) which is capable of being torn or ripped in order to hydrate the drug and electrolyte reservoirs (15, 16) and activate the device (10, 30). In another embodiment, the device (30) is held in a package (32). The device (30) has pouches (21, 22) which release their liquid contents automatically upon removal of the device (30) from the package (32). In yet another embodiment, the device (40) is held in a package (42) having a compression zone (46). The pouches (21, 22) must be moved through the compression zone (46) when removing the device (40) from the package (42).

Abstract: A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a semipermeable housing defining a internal space, (2) an optional and presently preferred in the space, (3) a heat responsive composition comprising a beneficial agent in the space, (4) a space consuming member in the device, (5) a non-toxic compound blended with the heat responsive composition for enhancing its viscosity; (6) an exit port in the wall for increasing the internal pressure of the dispenser and for simultaneously letting the beneficial agent exit through said port from the device, and (7) an embodiment comprising a prehydrating fluid for fastening the start-up of delivery from the delivery system.

Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.

Abstract: A method of manufacture of a semiconductor pellet of an electric surface-discharge igniter of a gas-turbine engine begins with a mixture of 60% by weight silicon-carbide particles of 600 British Standard Mesh size, and 40% by weight of powdered alumino-silicate or other silica glass, containing 85% silica. The mixture is heated to 1250.degree. C. to coat the silicon-carbide particles with silica, and then when cool is milled down to 150 British Standard Mesh size. After being mixed with an organic binder the mixture is dried and then sifted through a sieve of 30 British Standard mesh on to a sieve of 60 British Standard mesh. The portion of the material retained on the latter seive is compacted in a press under 50,000 pounds per square inch into the annular pellet-form and sintered to a temperature of 1500.degree. C. in a non-oxidizing atmosphere.