Abstract: There is provided a process for manufacture of optically-active, 2-(acyloxymethyl)-1,3-oxathiolanes of Formula I comprising a preparation of a racemic compound and an enzyme-catalyzed kinetic resolution of the enantiomers. The invention may further provide for the esterification and racemization of the by-product of the enzymatic reaction. In this manner, 2(R)-(benzoyloxymethyl)-1,3-oxathiolane is prepared as a useful intermediate for manufacture of the anti-HIV drug Apricitabine.

Abstract: There is provided a process for manufacture of optically-active, 2-(acyloxymethyl)-1,3-oxathiolanes of Formula I comprising a preparation of a racemic compound and an enzyme-catalyzed kinetic resolution of the enantiomers. The invention may further provide for the esterification and racemization of the by-product of the enzymatic reaction. In this manner, 2(R)-(benzoyloxymethyl)-1,3-oxathiolane is prepared as a useful intermediate for manufacture of the anti-HIV drug Apricitabine.

Abstract: There is provided a process for manufacture of optically-active, 2-(acyloxymethyl)-1,3-oxathiolanes of Formula I comprising a preparation of a racemic compound and an enzyme-catalyzed kinetic resolution of the enantiomers. The invention may further provide for the esterification and racemization of the by-product of the enzymatic reaction. In this manner, 2(R)-(benzoyloxymethyl)-1,3-oxathiolane is prepared as a useful intermediate for manufacture of the anti-HIV drug Apricitabine.

Abstract: The present invention is directed to a method for protecting metal surfaces in oil & gas exploration and production, refinery and petrochemical process applications subject to solid particulate erosion at temperatures of up to 1000° C. The method includes the step of providing the metal surfaces in such applications with a hot erosion resistant cermet lining or insert, wherein the cermet lining or insert includes a) about 30 to about 95 vol % of a ceramic phase, and b) a metal binder phase, wherein the cermet lining or insert has a HEAT erosion resistance index of at least 5.0 and a K1C fracture toughness of at least 7.0 MPa-m1/2. The metal surfaces may also be provided with a hot erosion resistant cermet coating having a HEAT erosion resistance index of at least 5.0.

Abstract: The present invention is directed to a method for protecting metal surfaces in oil & gas exploration and production, refinery and petrochemical process applications subject to solid particulate erosion at temperatures of up to 1000° C. The method includes the step of providing the metal surfaces in such applications with a hot erosion resistant cermet lining or insert, wherein the cermet lining or insert includes a) about 30 to about 95 vol % of a ceramic phase, and b) a metal binder phase, wherein the cermet lining or insert has a HEAT erosion resistance index of at least 5.0 and a K1C fracture toughness of at least 7.0 MPa-m1/2. The metal surfaces may also be provided with a hot erosion resistant cermet coating having a HEAT erosion resistance index of at least 5.0.

Abstract: The present invention is directed to a method for protecting metal surfaces in oil & gas exploration and production, refinery and petrochemical process applications subject to solid particulate erosion at temperatures of up to 1000° C. The method includes the step of providing the metal surfaces in such applications with a hot erosion resistant cermet lining or insert, wherein the cermet lining or insert includes a) about 30 to about 95 vol % of a ceramic phase, and b) a metal binder phase, wherein the cermet lining or insert has a HEAT erosion resistance index of at least 5.0 and a K1C fracture toughness of at least 7.0 MPa-m1/2. The metal surfaces may also be provided with a hot erosion resistant cermet coating having a HEAT erosion resistance index of at least 5.0.

Abstract: There is provided a method for manufacture of 2-oxoimidazolidines of Formula I comprising one or more of the steps of converting an amine to an acylation agent, condensation of the acylation agent with a bi-functional compound of structure L-C(R4)(R5)—C(R2)(R3)—NHR1, wherein L is a leaving group, and ring closure of the resulting urea. In this manner, certain 2-oxoimidazolidines may be manufactured that are useful intermediates for the production of Pramiconazole and structurally related compounds.

Abstract: There is provided a process for manufacture of optically-active, 2-(acyloxymethyl)-1,3-oxathiolanes of Formula I comprising a preparation of a racemic compound and an enzyme-catalyzed kinetic resolution of the enantiomers. The invention may further provide for the esterification and racemization of the by-product of the enzymatic reaction. In this manner, 2(R)-(benzoyloxymethyl)-1,3-oxathiolane is prepared as a useful intermediate for manufacture of the anti-HIV drug Apricitabine.

Abstract: Multimodal cermet compositions comprising a multimodal grit distribution of the ceramic phase and method of making are provided by the present invention. The multimodal cermet compositions include a) a ceramic phase and b) a metal binder phase, wherein the ceramic phase is a metal boride with a multimodal distribution of particles, wherein at least one metal is selected from the group consisting of Group IV, Group V, Group VI elements of the Long Form of The Periodic Table of Elements and mixtures thereof, and wherein the metal binder phase comprises at least one first element selected from the group consisting of Fe, Ni, Co, Mn and mixtures thereof, and at least second element selected from the group consisting of Cr, Al, Si and Y, and Ti.

Abstract: A tile for lining an internal surface in a heavy wear area. The tile includes at least one locating rod embedded within said tile and an internal mechanism for laterally extending said at least one locating rod out of said tile and into a gap in an adjoining structure which may be another tile. The tiles forming the lining surface are securely held in place as a result of the selective deployment of the locating rods into a gap in the adjoining structure.

Abstract: One form of the disclosure includes a cermet composition represented by the formula (PQ)(RS) comprising: a ceramic phase (PQ) and a binder phase (RS) wherein, P is a metal selected from the group consisting of Al, Si, Mg, Ca, Y, Fe, Mn, Group IV, Group V, Group VI elements, and mixtures thereof, Q is oxide, R is a base metal selected from the group consisting of Fe, Ni Co, Mn and mixtures thereof, S consists essentially of at least one element selected from Cr, Al and Si and at least one reactive wetting element selected from the group consisting of Ti, Zr, Hf, Ta, Sc, Y, La, and Ce, wherein the ceramic phase (PQ) ranges from about 55 to 95 vol % based on the volume of the cermet and is dispersed in the binder phase (RS) as particles with a diameter of 100 microns or greater. Another form of the disclosure relates to a bimodal size distribution of the metal oxide ceramic phase within the metal matrix phase.

Abstract: The present invention is directed to a method for protecting metal surfaces in oil & gas exploration and production, refinery and petrochemical process applications subject to solid particulate erosion at temperatures of up to 1000° C. The method includes the step of providing the metal surfaces in such applications with a hot erosion resistant cermet lining or insert, wherein the cermet lining or insert includes a) about 30 to about 95 vol % of a ceramic phase, and b) a metal binder phase, wherein the cermet lining or insert has a HEAT erosion resistance index of at least 5.0 and a K1C fracture toughness of at least 7.0 MPa-m 1/2. The metal surfaces may also be provided with a hot erosion resistant cermet coating having a HEAT erosion resistance index of at least 5.0.

Abstract: A tile anchoring system for use in reactors and other furnace like equipment which involves the use of a tile that contains various internal parts. According to the various embodiments of the present invention, the tile is formed as more than one part. In the present invention, various techniques and parts are used to anchor tiles to surfaces wherein the various parts and the tiles themselves “snap” into place with one another and/or with an existing hexmetal mesh structure.

Abstract: A tile anchoring system for use in reactors and other furnace like equipment which involves the use of a tile that contains various internal parts. According to the various embodiments of the present invention, the tile is formed as more than one part. In the present invention, various techniques and parts are used to anchor tiles to surfaces wherein the various parts and the tiles themselves “snap” into place with one another and/or with an existing hexmetal mesh structure.

Abstract: A detachable cushioned carpet section for marine use on a boat, in the helm area where a helmsman stands. The carpet section has a pad adhered to its underside to add foot comfort. The carpet section may fit with other removable carpet sections which are removably attached to the boat deck. The carpet sections are typically installed by snapping to the deck and removed by unsnapping for storage when not in use. The helm carpet has a pad which conforms generally to the shape of the carpet section leaving an unpadded border to allow the snap heads mounted along the carpet border to be snapped directly to the studs on the deck surface. The pad is inclined outward at its edges to allow a smooth transition for the supported carpeting from the main portion to the border. The carpet is of the outdoor type to withstand weather effects.

Abstract: New analogs of sampangine and cleistopholine, compositions and methods of preparation thereof, method of treating fungal and mycobacterial infections.

Abstract: Simply stated, the present invention contemplates the use of a ceramic fiber insulation material which is impregnated with an agent capable of stiffening the blanket and reducing erosion of the insulation material under conditions of use.

Abstract: The present invention provides a mechanism device for preventing gas channeling between the sidewall and a heat exchange tube bundle located in the convection section of a horizontal tube fired heater while permitting in-situ repair of the sidewall refractory. The invention comprises a plurality of serially elongated plate members pivotably mounted on a tube and sized longitudinally to extend at a predetermined distance from the tube to the sidewall of the convection section of the heater, the number of plate members being sufficient to extend for substantially the length of the tube.

Abstract: Ferroniobium, ferrotantalum and ferrovanadium alloys are hydrogenated to facilitate crushing then nitrided, and then acid-leached to produce a soluble iron nitride leachate and a niobium, tantalum or vanadium nitride residue which residue can be denitrided to yield the metal which can be recovered by melting.

Abstract: New analogs of sampangine and cleistopholine, compositions and methods of preparation thereof, method of treating fungal and mycobacterial infections. The compounds have the general formula: ##STR1## where the R.sub.1, R.sub.2, and R.sub.5 groups are defined herein.