Patents by Inventor John R. Regan

John R. Regan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,4-Disubstituted benzo-fused urea compounds
    Patent number: 6825184
    Abstract: Disclosed are compounds of the formulas (I) & (II) shown below which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds. wherein G, X, A and Q are described herein.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: November 30, 2004
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John R. Regan
  • Compounds useful as anti-inflammatory agents
    Patent number: 6660732
    Abstract: Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: December 9, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Rajashehar Betageri, Steffen Breitfelder, Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, Thomas M. Kirrane, Monica H. Moriak, Neil Moss, Usha R. Patel, John R. Proudfoot, John R. Regan, Rajiv Sharma, Sanxing Sun, Alan D. Swinamer, Hidenori Takahashi
  • 1,4-Disubstituted benzo-fused urea compounds
    Publication number: 20030162968
    Abstract: Disclosed are compounds of the formulas (I) & (II) shown below which are active as anti-inflammatory agents. Also disclosed are methods of using and making such compounds.
    Type: Application
    Filed: October 11, 2002
    Publication date: August 28, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John R. Regan
  • Compounds useful as anti-inflammatory agents
    Patent number: 6608052
    Abstract: Disclosed are novel aromatic compounds of the formula(I) wherein G, E, W, Ar, X, Y and Z. The compounds are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: August 19, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Steffen Breitfelder, Pier F. Cirillo, John R. Regan
  • Aromatic heterocyclic compounds as antiinflammatory agents
    Patent number: 6506748
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: January 14, 2003
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Eugene R. Hickey, John R. Regan
  • Aromatic heterocyclic compounds as anti-inflammatory agents
    Patent number: 6476023
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: November 5, 2002
    Assignee: Boehringen Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier F. Cirillo, Eugene R. Hickey, John R. Regan
  • Compounds useful as anti-inflammatory agents
    Publication number: 20020082256
    Abstract: Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Application
    Filed: September 25, 2001
    Publication date: June 27, 2002
    Inventors: Rajashehar Betageri, Steffen Breitfelder, Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, Thomas M. Kirrane, Monica H. Moriak, Neil Moss, Usha R. Patel, John R. Proudfoot, John R. Regan, Rajiv Sharma, Sanxing Sun, Alan D. Swinamer, Hidenori Takahashi
  • Aromatic heterocyclic compounds as antiinflammatory agents
    Publication number: 20020065285
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Application
    Filed: June 26, 2001
    Publication date: May 30, 2002
    Inventors: Eugene R. Hickey, John R. Regan
  • Aromatic heterocyclic compounds as antiinflammatory agents
    Publication number: 20020058678
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1, Ar2, L, Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Application
    Filed: June 12, 2001
    Publication date: May 16, 2002
    Inventors: Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, John R. Regan, Lin-Hua Zhang
  • Compounds useful as anti-inflammatory agents
    Publication number: 20020055507
    Abstract: Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Application
    Filed: September 25, 2001
    Publication date: May 9, 2002
    Inventors: Rajashehar Betageri, Steffen Breitfelder, Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, Thomas M. Kirrane, Monica H. Moriak, Neil Moss, Usha R. Patel, John R. Proudfoot, John R. Regan, Rajiv Sharma, Sanxing Sun, Alan D. Swinamer, Hidenori Takahashi
  • Aromatic heterocyclic compounds as antiinflammatory agents
    Patent number: 6372773
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: April 16, 2002
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventor: John R. Regan
  • Compounds useful as anti-inflammatory agents
    Patent number: 6358945
    Abstract: Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: March 19, 2002
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Steffen Breitfelder, Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, John R. Proudfoot, John R. Regan, Alan D. Swinamer, Hidenori Takahashi
  • Compounds useful as anti-inflammatory agents
    Publication number: 20020032195
    Abstract: Disclosed are novel aromatic compounds of the formula(I) wherein G, E, W, Ar, X, Y and Z. The compounds are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.
    Type: Application
    Filed: April 13, 2001
    Publication date: March 14, 2002
    Inventors: Steffen Breitfelder, Pier F. Cirillo, John R. Regan
  • Method of treating cytokine mediated diseases or conditions
    Patent number: 6333325
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: December 25, 2001
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, John R. Regan, Lin-Hua Zhang
  • Aromatic heterocyclic compounds as antiinflammatory agents
    Patent number: 6329415
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: December 11, 2001
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier F. Cirillo, John R. Regan
  • Aromatic heterocyclic compound as antiinflammatory agents
    Patent number: 6319921
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula (I) wherein Ar1, Ar2, L, Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: November 20, 2001
    Assignee: Boerhinger Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier F. Cirillo, Thomas A. Gilmore, Eugene R. Hickey, John R. Regan, Lin-Hua Zhang
  • Aromatic heterocyclic compounds and their use as anti-inflammatory agents
    Publication number: 20010039290
    Abstract: Novel aromatic heterocyclic compounds inhibit cytokines production involved in immunoregulation and inflammation such as interleukin-1 and tumor necrosis factor production. The compounds are therefore useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.
    Type: Application
    Filed: March 14, 2001
    Publication date: November 8, 2001
    Inventors: John R. Regan, Eugene R. Hickey, Neil Moss, Charles L. Cywin, Christopher Pargellis, Thomas A. Gilmore
  • Aromatic heterocyclic compounds as anti-inflammatory agents
    Patent number: 6297381
    Abstract: Disclosed are novel aromatic heterocyclic compounds of the formula(I) wherein Ar1,Ar2,L,Q and X are described herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: October 2, 2001
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier F. Cirillo, Eugene R. Hickey, John R. Regan
  • Polycyclo heterocyclic derivatives as antiinflammatory agents
    Patent number: 6242453
    Abstract: Disclosed are novel aromatic polycyclo heterocyclic compounds of the formula(I) wherein A, B, C, G, Ar, L, Q and X are described herein. The compounds are useful in pharmaceutical compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes of making such compounds.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: June 5, 2001
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc
    Inventors: Pier F. Cirillo, Eugene R. Hickey, John R. Regan, Lin-Hua Zhang
  • Aromatic heterocyclic compounds and their use as anti-inflammatory agents
    Patent number: 6228881
    Abstract: Novel aromatic heterocyclic compounds inhibit cytokines production involved in immunoregulation and inflammation such as interleukin-1 and tumor necrosis factor production. The compounds are therefore useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: May 8, 2001
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: John R. Regan, Pier F. Cirillo, Eugene R. Hickey, Neil Moss, Charles L. Cywin, Christopher Pargellis, Thomas A. Gilmore