Patents by Inventor John R Rizzo

John R Rizzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-peptidyl vasopressin V1A antagonists
    Patent number: 6610680
    Abstract: This invention provides substituted 2-(azetidinon-1-yl) acetic acid derivatives of Formula II for the antagonism of the vasopressin V1a receptor.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: August 26, 2003
    Assignee: Eli Lilly and Company
    Inventors: Robert F Bruns, Jr., Robin D G Cooper, Bruce A Dressman, David C Hunden, Stephen W Kaldor, Gary A Koppel, John R Rizzo, Jeffrey J Skelton, Mitchell I Steinberg
  • Non-peptidyl vasopressin V1a antagonists
    Patent number: 6521611
    Abstract: This invention provides methods and 2-(azetidin-2-on-1-yl) acetic acid derivatives of Formula I for the antagonism of the vasopressin V1a receptor.
    Type: Grant
    Filed: December 8, 2000
    Date of Patent: February 18, 2003
    Assignee: Eli Lilly and Company
    Inventors: Robert F Bruns, Jr., Robin D G Cooper, Bruce A Dressman, David C Hunden, Stephen W Kaldor, Gary A Koppel, John R Rizzo, Jeffrey J Skelton, Mitchell I Steinberg
  • Non-peptidyl vasopressin V1a antagonists
    Publication number: 20020049187
    Abstract: This invention provides methods and 2-(azetidin-2-on-1-yl) acetic acid derivatives of Formula I 1
    Type: Application
    Filed: December 8, 2000
    Publication date: April 25, 2002
    Inventors: Robert F. Bruns, Robin DG Cooper, Bruce A. Dressman, David C. Hunden, Stephen W. Kaldor, Gary A. Koppel, John R. Rizzo, Jeffrey J. Skelton, Mitchell I. Steinberg
  • Non-peptidyl vasopressin V1a antagonists
    Patent number: 6204260
    Abstract: This invention provides methods and 2-(azetidin-2-on-1-yl)acetic acid derivatives for the antagonism of the vasopressin V1a receptor.
    Type: Grant
    Filed: August 19, 1999
    Date of Patent: March 20, 2001
    Assignee: Eli Lilly and Company
    Inventors: Robert F Bruns, Jr., Robin DG Cooper, Bruce A Dressman, David C Hunden, Stephen W Kaldor, Gary A Koppel, John R Rizzo, Jeffrey J Skelton, Mitchell I Steinberg
  • Azetidinone intermediates to carbacephalosporins and process
    Patent number: 5637692
    Abstract: 7.beta.-Amino-3-hydroxy-1-carba(1-dethia)-3-cephem-4-carboxylic acid esters are provided via cyclization of cis-3-(substituted amino)-1-(2-substituted 2-oxoethyl)-4-substituted azetidinones. The 7.beta.-amino-3-hydroxy-1-carba (1-dethia)-3-cephem-4-carboxylic acid esters are useful chiral intermediates to .beta.-lactam antibiotics.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: June 10, 1997
    Assignee: Eli Lilly and Company
    Inventors: James Aikins, John P. Gardner, Billy G. Jackson, John R. Rizzo, Eddie V. Tao
  • Azetidinone intermediates to carbacephalosporins and process
    Patent number: 5453503
    Abstract: 7.beta.-Amino-3-hydroxy-1-carba(1-dethia)-3-cephem-4-carboxylic acid esters are provided via cyclization of cis-3-(substituted amino)-1-(2-substituted 2-oxoethyl)-4-substituted azetidinones. The 7.beta.-amino-3-hydroxy-1-carba(1-dethia)-3-cephem-4-carboxylic acid esters are useful chiral intermediates to .beta.-lactam antibiotics.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: September 26, 1995
    Assignee: Eli Lilly and Company
    Inventors: James Aikins, John P. Gardner, Billy G. Jackson, John R. Rizzo, Eddie V. Tao
  • 1,3,4 substituted and bicyclic derivatives of 2-azetidinones and processes for preparation thereof
    Patent number: 5453502
    Abstract: The invention provides 1,3,4 substituted and bicyclic derivatives of 2-azetidinones and processes therefor. These compounds are valuable intermediates useful in the preparation of 1-carba(dethia)cephalosporin antibiotics.
    Type: Grant
    Filed: March 16, 1994
    Date of Patent: September 26, 1995
    Assignee: Eli Lilly and Company
    Inventors: James A. Aikins, Larry C. Blaszczak, Kevin P. Lund, John R. Rizzo
  • Process for preparing 5-cyano-4, 5-dihydro-3,4-dicarboxypyrazole derivatives
    Patent number: 4924001
    Abstract: The present invention provides 5-cyano-4,5-dihydro-3,4-dicarboxypyrazoles and a process for preparing such compounds which comprises reacting a dialkyl fumarate with diazoacetonitrile.
    Type: Grant
    Filed: October 17, 1989
    Date of Patent: May 8, 1990
    Assignee: Eli Lilly and Company
    Inventors: John R. Rizzo, Eddie V. P. Tao
  • 5-cyano-4,5-dihydro-3,4-dicarboxypyrazole derivatives
    Patent number: 4892956
    Abstract: The present invention provides 5-cyano-4,5-dihydro-3,4-dicarboxypyrazoles and a process for preparing such compounds which comprises reacting a dialkyl fumarate with diazoacetonitrile.
    Type: Grant
    Filed: November 7, 1988
    Date of Patent: January 9, 1990
    Assignee: Eli Lilly and Company
    Inventors: John R. Rizzo, Eddie V. P. Tao