Patents by Inventor John R. Vose

John R. Vose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acellular pertussis vaccines and methods of preparation thereof
    Patent number: 6399076
    Abstract: Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70% of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material.
    Type: Grant
    Filed: June 9, 1998
    Date of Patent: June 4, 2002
    Assignee: Aventis Pasteur Limited
    Inventors: John R. Vose, Raafat E. F. Fahim, Gail E. D. Jackson, Larry U. L. Tan, Andrew Herbert, Leslie Boux, Luis Barreto, John Thipphawong, Michel H. Klein
  • ACELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF
    Publication number: 20010009666
    Abstract: Acellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70% of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material.
    Type: Application
    Filed: June 9, 1998
    Publication date: July 26, 2001
    Inventors: JOHN R VOSE, RAAFAT E F FAHIM, GAIL E D JACKSON, LARRY U L TAN, ANDREW HERBERT, LESLIE BOUX, LUIS BARRETO, JOHN THIPPHAWONG, MICHEL H KLEIN
  • Acellular pertussis vaccines and methods of preparing thereof
    Patent number: 5877298
    Abstract: A fimbrial agglutinogen preparation is prepared from a bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material. The fimbrial agglutinogen preparation may be used to prepare acellular pertussis vaccines with other pertussis antigens, including pertussis toxin or toxoid thereof, the 69 kDa protein and filamentous hemagglutinin and other Bordetella antigens.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: March 2, 1999
    Inventors: Raafat E. F. Fahim, John R. Vose, John Thipphawong, Luis Barreto, Gail E. D. Jackson, Larry U. L. Tan, Andrew Herbert, Michel H. Klein