Patents by Inventor John R. Waters
John R. Waters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 5624814Abstract: A nutrient culture medium which isolates antibiotics and other microbial growth inhibitors during culturing of a microorganism is shown. The culture medium includes an aqueous dispersion of nutrient materials and an effective amount of an isolating substance or substances capable of isolating antimicrobial materials during culturing of a microorganism.The isolating substances are selected from ion exchange resins and non-functional adsorbent resins.Type: GrantFiled: October 19, 1994Date of Patent: April 29, 1997Assignee: Becton Dickinson and CompanyInventors: John R. Waters, Rodney Broman
-
Patent number: 5051360Abstract: Gas-generating or absorbing activity of microorganisms is detected by providing a vessel in which the microorganisms are incubated, the vessel having a cap with a membrane indicator therein. The membrane has a deformed region which is inflated to indicate the existence of a change in pressure within the vessel as compared with ambient pressure. Automatic monitoring of the inflated portion is disclosed.Type: GrantFiled: April 24, 1990Date of Patent: September 24, 1991Assignee: Abo, Inc.Inventor: John R. Waters
-
Patent number: 4952498Abstract: Gas-generating activity of microorganisms is detected by providing a vessel in which the microorganisms are incubated, the vessel having a cap with a membrane indicator therein. The membrane has a deformed region which is inflated to indicate the existence of an increase in pressure within the vessel as compared with ambient pressure. Visual or automatic monitoring of the inflated portion is disclosed.Type: GrantFiled: May 6, 1988Date of Patent: August 28, 1990Inventor: John R. Waters
-
Patent number: 4730624Abstract: A vacuum blood collection system is provided. The blood collection system contains an evacuated sample collection container which is open at both ends. One end of the container is closed by a self-sealing puncturable stopper adapted to be penetrated by one end of a double ended needle. The other end of the collection container is closed by a slidable sealing stopper affixed to a plunger to provide a piston assembly. The blood collection system also includes restraining means to prevent premature movement of the slidable sealing stopper and may contain a temporary seal to prevent movement of the piston assembly prior to the need for removing the blood specimen from the collection container.Type: GrantFiled: August 22, 1983Date of Patent: March 15, 1988Assignee: Becton, Dickinson and CompanyInventor: John R. Waters
-
Patent number: 4632902Abstract: A method of detections biological activity is disclosed. A nutrient growth medium which isolates antibiotics and other microbial growth inhibitors during culturing of a microorganism. The growth medium includes an aqueous dispersion of nutrient materials and an effective amount of an isolating substance or substances capable of isolating antimicrobial materials during culturing of a microorganism. The isolating substances are selected from ion exchange resins and non-functional adsorbent resins.Type: GrantFiled: January 3, 1985Date of Patent: December 30, 1986Assignee: Becton, Dickinson and CompanyInventors: John R. Waters, Rodney Broman
-
Patent number: 4624648Abstract: A rotary aerial toy comprising a tubular sleeve of flexible material and of circular cross section. In one form of the invention the tubular sleeve tapers from one end toward the other with air entering the larger head end and moving toward the tail end. The head end is adapted for a bridle connection for supporting the sleeve for wind passage therethrough. The sleeve comprises plural strips extending at least generally longitudinally of the sleeve with each strip being of substantially right triangular form, at least at the head end portion thereof. The strips are connected to one another with the hypotenuse leg of one strip being connected to the altitude leg of an adjacent strip and with the base leg being transverse. The strips are arranged at assembly with a step between the head ends of adjacent strips and the seams connecting any selected pair of strips stop short of the head end of the altitude leg of the strip.Type: GrantFiled: June 24, 1985Date of Patent: November 25, 1986Assignee: Catch the Wind Kite Shops, Inc.Inventor: John R. Waters
-
Patent number: 4257187Abstract: A pair of arched wings are secured together at their inner ends by a connecting member to form a body portion. A weight is secured to the body portion to provide proper balance in flight. The wings have an upwardly arched configuration which may be accomplished either by molding them in such configuration or by constructing them from a blank which has a curvature therein such as from a cylindrical tubular member. In one embodiment, the wings have a reduced radius toward the front to provide a hang glider type construction which requires no tail.Type: GrantFiled: October 2, 1978Date of Patent: March 24, 1981Inventor: John R. Waters
-
Patent number: 4182656Abstract: A sample of material to be tested for the presence of biologically active agents, such as bacteria, is introduced into a sealable container partially filled with a culture medium comprising a .sup.13 C-labeled fermentable substrate, the remainder of the container being filled with a culture gas, the container and its contents are subjected to conditions conducive to biological activity for a predetermined period sufficient for fermentation of the medium to produce carbon dioxide after which the ratio of .sup.13 CO.sub.2 to .sup.12 CO.sub.2 in the culture gas in the container is determined and compared to the initial ratio of .sup.13 CO.sub.2 to .sup.12 CO.sub.2 in the culture gas in order to detect any differences indicating the presence of biologically active agents in the sample.Type: GrantFiled: September 10, 1976Date of Patent: January 8, 1980Assignee: Johnston Laboratories, Inc.Inventors: Joseph E. Ahnell, Rodney L. Broman, John R. Waters
-
Patent number: 4122626Abstract: A pair of arched wings are secured together at their inner ends by a connecting member to form a body portion. A weight is secured to the body portion to provide proper balance in flight. The wings have an upwardly arched configuration which may be accomplished either by molding them in such configuration or by constructing them from a blank which has a curvature therein such as from a cylindrical tubular member. In one embodiment, the wings have a reduced radius toward the front to provide a hang glider type construction which requires no tail.Type: GrantFiled: October 4, 1976Date of Patent: October 31, 1978Inventor: John R. Waters
-
Patent number: 4073691Abstract: A sample of material to be tested for the presence of biologically active agents, such as bacteria, is introduced into a sealable container partially filled with a culture medium; the remainder of the container being filled with a culture gas, the container and its contents are subjected to conditions conducive to biological activity for a predetermined period sufficient for fermentation of the medium to produce at least one gaseous product after which the character of the culture gas in the container is determined and compared to the initial character of the culture gas in order to detect any differences caused by changes in the composition of the culture gas indicating the presence or absence of biologically active agents in the sample.Type: GrantFiled: August 24, 1976Date of Patent: February 14, 1978Assignee: Johnston Laboratories, Inc.Inventors: Joseph E. Ahnell, Rodney L. Broman, John R. Waters
-
Patent number: 4073694Abstract: A method of measuring the level of an aminoglycoside antibiotic, such as gentamicin, tobramycin or amikacin, in blood serum or plasma comprising incubating an aliquot of blood serum or plasma from a human patient being treated with an aminoglycoside antibiotic in a urea-containing culture medium with a susceptible strain of an adaptive urease producing microorganism corresponding to Proteus rettgeri JLI 03, ATCC No. 31168.Type: GrantFiled: April 5, 1976Date of Patent: February 14, 1978Assignee: Johnston Laboratories, Inc.Inventors: Dennis Buda, Rodney L. Broman, John R. Waters
-
Patent number: 3997404Abstract: A method for characterization of biological activity comprising providing a plurality of gas-tight cells each having a light-permeable wall section, each cell containing a different .sup.14 C-labeled fermentable substrate, a carbon dioxide absorber and a scintillation compound in intimate proximity to each other remote from said substrate, and an axenic sample of a biologically active material; subjecting said cells to conditions conducive to biological activity and thereafter measuring the light emitted by the scintillation compound as a result of the decay of .sup.14 CO.sub.2 generated by the metabolic action of the biologically active agent in said sample on said substrate and captured by the carbon dioxide absorber. Apparatus is provided comprising a plurality of sterile chambers containing different .sup.Type: GrantFiled: May 27, 1975Date of Patent: December 14, 1976Assignee: Johnston Laboratories, Inc.Inventor: John R. Waters
-
Patent number: 3944471Abstract: A sample of materials such as blood, urine, spinal fluid, or the like to be tested for the presence of biological activity is placed into a first sterile container with a suitable growth medium which includes a .sup.14 C carbon containing carbon source (such as .sup.14 C substituted glucose) which is fermentable to produce gaseous .sup.14 CO.sub.2. This first container is placed within a second container which also contains CO.sub.2 -absorbing material associated with a scintillation compound. The gaseous .sup.14 CO.sub.2 generated in the first container diffuses into the outer container where it is absorbed and held in contact with the scintillation compound. The decay of .sup.14 C will cause the scintillation compounds to emit light flashes which can be detected by a scintillation counter. Thus, the presence of .sup.14 CO.sub.2 is detected in the same container in which the reaction is taking place.Type: GrantFiled: June 7, 1974Date of Patent: March 16, 1976Assignee: Johnston Laboratories, Inc.Inventor: John R. Waters
-
Patent number: 3935073Abstract: A sample of material such as blood, urine, spinal fluid, or the like to be tested for the presence of biological activity is placed into a sterile container together with a suitable growth medium which includes a C.sup.14 carbon containing carbon source (such as C.sup.14 substituted glucose) which is fermentable to produce gaseous C.sup.14 O.sub.2. An incubator is provided for exposing the container and its contents to conditions conducive to growth. After a suitable incubation period, a portion of the gaseous atmosphere in the container is withdrawn and analyzed in gaseous form in an ionization chamber for the presence of radioactivity. Valve and conduit means are provided for analyzing a number of samples sequentially.Type: GrantFiled: September 22, 1971Date of Patent: January 27, 1976Assignee: Johnston Laboratories, Inc.Inventor: John R. Waters